Peter L. Pedersen

Overview

Best Publications

• Ion motive ATPases. I. Ubiquity, properties, and significance to cell function

  Peter L. Pedersen;Ernesto Carafoli

  1354
  Citations

• Tumor mitochondria and the bioenergetics of cancer cells.

  Peter L. Pedersen

  1053
  Citations

• Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

  S P Mathupala;Y H Ko;P L Pedersen

  1017
  Citations

• The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.

  R. R. H. Anholt;P. L. Pedersen;E. B. De Souza;S. H. Snyder

  896
  Citations

• Defective protein folding as a basis of human disease

  Philip J. Thomas;Bao He Qu;Peter L. Pedersen

  786
  Citations

• Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy.

  Saroj P. Mathupala;Young H. Ko;Peter L. Pedersen

  703
  Citations

• Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers’ most common phenotypes, the “Warburg Effect”, i.e., elevated glycolysis in the presence of oxygen

  Peter L. Pedersen

  573
  Citations

• High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

  Ernesto Bustamante;Peter L. Pedersen

  515
  Citations

• Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues.

  Peter L. Pedersen;John W. Greenawalt;Baltazar Reynafarje;Joanne Hullihen

  510
  Citations

• Glucose Catabolism in Cancer Cells IDENTIFICATION AND CHARACTERIZATION OF A MARKED ACTIVATION RESPONSE OF THE TYPE II HEXOKINASE GENE TO HYPOXIC CONDITIONS

  Saroj P. Mathupala;Annette Rempel;Peter L. Pedersen

  485
  Citations

• Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP.

  Young H. Ko;Barbara L. Smith;Yuchuan Wang;Martin G. Pomper

  456
  Citations

• Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP.

  K K Arora;P L Pedersen

  449
  Citations

• Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention.

  Peter L Pedersen;Saroj Mathupala;Annette Rempel;J.F Geschwind

  445
  Citations

• Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase.

  Young Hee Ko;Peter L. Pedersen;J.F. Geschwind

  442
  Citations

• ATP Synthase and the Actions of Inhibitors Utilized To Study Its Roles in Human Health, Disease, and Other Scientific Areas

  Sangjin Hong;Peter L. Pedersen

  380
  Citations

• Energy metabolism of tumor cells. Requirement for a form of hexokinase with a propensity for mitochondrial binding.

  E Bustamante;H P Morris;P L Pedersen

  366
  Citations

• Aberrant glycolytic metabolism of cancer cells: A remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for Type II hexokinase

  Saroj P. Mathupala;Annette Rempel;Peter L. Pedersen

  349
  Citations

• Glucose Catabolism in Cancer Cells.: ISOLATION, SEQUENCE, AND ACTIVITY OF THE PROMOTER FOR TYPE II HEXOKINASE *

  Saroj P. Mathupala;Annette Rempel;Peter L. Pedersen

  347
  Citations

• Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production.

  Jean Francois H. Geschwind;Young H. Ko;Michael S. Torbenson;Carolyn Magee

  346
  Citations

• PROTON ATPASES: STRUCTURE AND MECHANISM

  L M Amzel;P L Pedersen

  331
  Citations