World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
43
Citations
9925
World Ranking
4280
National Ranking
1848

Research.com Recognitions

  • 2019 - Fellow of John Simon Guggenheim Memorial Foundation
  • 2008 - Fellow of Alfred P. Sloan Foundation

Overview

Patricia J. Wittkopp is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, accumulating a total of 67 publications in these fields. Wittkopp's work focuses extensively on molecular biology and genetics, with additional contributions in insect science, ecology, evolution, behavior, systematics, and plant science.

The main topics covered in Wittkopp's research include:

  • Genomics and chromatin dynamics
  • CRISPR and genetic engineering
  • Genetic diversity and population structure
  • Fungal and yeast genetics research
  • RNA and protein synthesis mechanisms
  • Evolution and genetic dynamics
  • Animal behavior and reproduction

Wittkopp has published articles in a range of scientific venues, often contributing to journals that focus on genetics and molecular biology. Frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Cell Systems
  • Philosophical Transactions of the Royal Society B Biological Sciences
  • Nature Reviews Genetics

Selected recent publications exemplify the scope and focus of Wittkopp's research:

  • "Molecular and evolutionary processes generating variation in gene expression," 2020, Nature Reviews Genetics
  • "Pleiotropic effects of trans-regulatory mutations on fitness and gene expression," 2022, Science
  • "Evolution of transcription factor binding through sequence variations and turnover of binding sites," 2022, Genome Research
  • "ebony Affects Pigmentation Divergence and Cuticular Hydrocarbons in Drosophila americana and D. novamexicana," 2020, Frontiers in Ecology and Evolution
  • "Mutational sources of trans-regulatory variation affecting gene expression in Saccharomyces cerevisiae," 2021, eLife

Throughout their career, Wittkopp has collaborated frequently with several researchers, demonstrating a networked approach to scientific inquiry. Notable coauthors include:

  • Mohammad A. Siddiq
  • Pétra Vande Zande
  • Fabien Duveau
  • Abigail M. Lamb
  • Mark S. Hill

Recognition of Wittkopp's contributions includes fellowships from established foundations. They were named a Fellow of the John Simon Guggenheim Memorial Foundation in 2019 and a Fellow of the Alfred P. Sloan Foundation in 2008.

Best Publications

  • Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence

    Patricia J. Wittkopp;Gizem Kalay

  • Evolutionary changes in cis and trans gene regulation

    Patricia J. Wittkopp;Belinda K. Haerum;Andrew G. Clark

  • Chance caught on the wing: cis -regulatory evolution and the origin of pigment patterns in Drosophila

    Nicolas Gompel;Benjamin Prud'homme;Benjamin Prud'homme;Patricia J. Wittkopp;Patricia J. Wittkopp;Victoria A. Kassner

  • Regulatory divergence in Drosophila revealed by mRNA-seq

    C. Joel McManus;Joseph D. Coolon;Michael O. Duff;Jodi Eipper-Mains

  • Regulatory changes underlying expression differences within and between Drosophila species

    Patricia J Wittkopp;Patricia J Wittkopp;Belinda K Haerum;Belinda K Haerum;Andrew G Clark

  • Reciprocal functions of the Drosophila yellow and ebony proteins in the development and evolution of pigment patterns

    Patricia J. Wittkopp;John R. True;John R. True;Sean B. Carroll

  • Evolution in black and white: genetic control of pigment patterns in Drosophila

    Patricia J. Wittkopp;Sean B. Carroll;Artyom Kopp

  • Development and evolution of insect pigmentation: genetic mechanisms and the potential consequences of pleiotropy.

    Patricia J. Wittkopp;Patrícia Beldade;Patrícia Beldade

  • Evolution of yellow Gene Regulation and Pigmentation in Drosophila

    Patricia J. Wittkopp;Kathy Vaccaro;Sean B. Carroll

  • Compensatory cis-trans Evolution and the Dysregulation of Gene Expression in Interspecific Hybrids of Drosophila

    Christian R. Landry;Patricia J. Wittkopp;Clifford H. Taubes;Jose M. Ranz

  • Drosophila pigmentation evolution: divergent genotypes underlying convergent phenotypes.

    Patricia J. Wittkopp;Barry L. Williams;Jayne E. Selegue;Sean B. Carroll

  • Evaluating the role of natural selection in the evolution of gene regulation

    J C Fay;P J Wittkopp

  • Molecular and evolutionary processes generating variation in gene expression

    Mark S. Hill;Pétra Vande Zande;Patricia J. Wittkopp

  • Tempo and mode of regulatory evolution in Drosophila

    Joseph D. Coolon;C. Joel McManus;C. Joel McManus;Kraig R. Stevenson;Brenton R. Graveley

  • Intraspecific polymorphism to interspecific divergence: genetics of pigmentation in Drosophila.

    Patricia J. Wittkopp;Emma E. Stewart;Lisa L. Arnold;Adam H. Neidert

  • Selection on noise constrains variation in a eukaryotic promoter

    Brian P. H. Metzger;David C. Yuan;Jonathan D. Gruber;Fabien Duveau

  • Sources of bias in measures of allele-specific expression derived from RNA-seq data aligned to a single reference genome

    Kraig R Stevenson;Joseph D Coolon;Patricia J Wittkopp

  • A gene necessary for normal male courtship, yellow, acts downstream of fruitless in the Drosophila melanogaster larval brain.

    Mark David Drapeau;Anna Radovic;Patricia J. Wittkopp;Anthony D. Long

  • The Genetic Basis of Pigmentation Differences Within and Between Drosophila Species.

    Jonathan Massey;Patricia J. Wittkopp

  • Regulatory divergence in Drosophila revealed by mRNA-seq (Genome Research (2010) 20, (816-825))

    C. Joel McManus;Joseph D. Coolon;Michael O. Duff;Jodi Eipper-Mains

Frequent Co-Authors

David L. Stern
David L. Stern Howard Hughes Medical Institute
Brenton R. Graveley
Brenton R. Graveley University of Connecticut Health Center
andrew g clark
andrew g clark Cornell University
Sean B. Carroll
Sean B. Carroll University of Maryland, College Park
Christian R. Landry
Christian R. Landry Université Laval
Jun Li
Jun Li University of Oklahoma Health Sciences Center
Daniel L. Hartl
Daniel L. Hartl Harvard University
Anthony D. Long
Anthony D. Long University of California, Irvine
Zinan Wang
Zinan Wang University of Electronic Science and Technology of China
Graeme I. Bell
Graeme I. Bell University of Chicago

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