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Mario U. Dianzani

Mario U. Dianzani

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
13088
World Ranking
8824
National Ranking
240

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Mario U. Dianzani mostly deals with Lipid peroxidation, Biochemistry, 4-Hydroxynonenal, Microsome and Hepatocyte. His study in Lipid peroxidation is interdisciplinary in nature, drawing from both Malondialdehyde and Carbon tetrachloride. Mario U. Dianzani conducts interdisciplinary study in the fields of Biochemistry and In vivo through his research.

Mario U. Dianzani combines subjects such as Gene expression, Cell growth, Molecular biology, Cell biology and Adenylate kinase with his study of 4-Hydroxynonenal. His Microsome research is multidisciplinary, incorporating elements of Ethanol, Tocopherol, Incubation, Cytochrome and Radical. His Hepatocyte research focuses on Membrane potential and how it connects with Glutamate dehydrogenase, Inner mitochondrial membrane, Cyclosporin a and Calcium in biology.

His most cited work include:

  • Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes. (523 citations)
  • Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions. (329 citations)
  • Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. (304 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Lipid peroxidation, 4-Hydroxynonenal, Internal medicine and Endocrinology are his primary areas of study. His Biochemistry and Hepatocyte, Microsome, Glutathione, Enzyme and Cytosol investigations all form part of his Biochemistry research activities. His studies deal with areas such as Cytochrome and Spin trapping as well as Microsome.

His Glutathione study integrates concerns from other disciplines, such as Malondialdehyde and Pharmacology. He performs multidisciplinary studies into Lipid peroxidation and In vivo in his work. His 4-Hydroxynonenal research includes themes of Cancer research, Gene expression, Cell growth, Molecular biology and Cell biology.

He most often published in these fields:

  • Biochemistry (58.53%)
  • Lipid peroxidation (49.31%)
  • 4-Hydroxynonenal (24.42%)

What were the highlights of his more recent work (between 1998-2012)?

  • 4-Hydroxynonenal (24.42%)
  • Lipid peroxidation (49.31%)
  • Cell growth (11.98%)

In recent papers he was focusing on the following fields of study:

His main research concerns 4-Hydroxynonenal, Lipid peroxidation, Cell growth, Cell biology and Biochemistry. Mario U. Dianzani has researched 4-Hydroxynonenal in several fields, including Cancer research, Hepatic stellate cell, Molecular biology, Growth inhibition and Cyclin. His Lipid peroxidation research integrates issues from Arachidonic acid, Phospholipase C and Polyunsaturated fatty acid.

His work carried out in the field of Cell growth brings together such families of science as Apoptosis, E2F, Phosphorylation and Cyclin D1, Cyclin D. The Apoptosis study combines topics in areas such as Endocrinology and Internal medicine. His Cell biology research includes elements of Peroxisome proliferator-activated receptor, microRNA, Cellular differentiation and Cyclin D2.

Between 1998 and 2012, his most popular works were:

  • 4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications. (235 citations)
  • 4-hydroxynonenal from pathology to physiology. (118 citations)
  • 4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells (107 citations)

Best Publications

  • Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes.

    H Esterbauer;K H Cheeseman;M U Dianzani;G Poli

  • Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions.

    G Poli;M U Dianzani;K H Cheeseman;T F Slater

  • The role of lipid peroxidation in liver damage

    Giuseppe Poli;Emanuele Albano;Mario U. Dianzani

  • Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells.

    M. Parola;M. Pinzani;A. Casini;E. Albano

  • Vitamin E dietary supplementation protects against carbon tetrachloride—induced chronic liver damage and cirrhosis

    Maurizio Parola;Gabriella Marisa Leonarduzzi;Fiorella Biasi;E Albano

  • 4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications.

    Maurizio Parola;Giorgio Bellomo;Gaia Robino;Giuseppina Barrera

  • Lipid peroxidation and cancer

    Mario Umberto Dianzani

  • Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells

    F. Marra;A. Gentilini;M. Pinzani;Goutam Ghosh Choudhury

  • On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis

    Maurizio Parola;Gabriella Leonarduzzi;Gaia Robino;Emanuele Albano

  • Lipid peroxidation in ethanol poisoning: a critical reconsideration.

    Dianzani Mu

  • Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols

    Emanuele Albano;Aldo Tomasi;Jan-Olov Persson;Ylva Terelius

  • 4-hydroxynonenal from pathology to physiology.

    Mario Umberto Dianzani

  • Lipid peroxidation: control of cell proliferation, cell differentiation and cell death.

    Giuseppina Barrera;Stefania Pizzimenti;Mario Umberto Dianzani

  • Studies on fatty liver with isolated hepatocytes. II. The action of carbon tetrachloride on lipid peroxidation, protein, and triglyceride synthesis and secretion.

    Giuseppe Poli;Enrico Gravela;Emanuele Albano;Mario U. Dianzani

  • Spin trapping of free radical species produced during the microsomal metabolism of ethanol.

    E. Albano;A. Tomasi;L. Goria-Gatti;M.U. Dianzani

  • Chemotactic activity of the lipid peroxidation product 4-hydroxynonenal and homologous hydroxyalkenals.

    Curzio M;Esterbauer H;Di Mauro C;Cecchini G

  • Effects of 4-hydroxynonenal on adenylate cyclase and 5'-nucleotidase activities in rat liver plasma membranes.

    Luciana Paradisi;Carla Panagini;Maurizio Parola;Giuseppina Barrera

  • 4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells

    Elena Zamara;Erica Novo;Fabio Marra;Alessandra Gentilini

  • In vivo and in vitro evidence concerning the role of lipid peroxidation in the mechanism of hepatocyte death due to carbon tetrachloride.

    Fiorella Biasi;Emanuele Albano;Elena Chiarpotto;Francesco P. Corongiu

  • 4-Hydroxynonenal and Cell Signalling

    Mario Umberto Dianzani

Frequent Co-Authors

Emanuele Albano
Emanuele Albano University of Eastern Piedmont Amadeo Avogadro
Giuseppe Poli
Giuseppe Poli University of Turin
Fiorella Biasi
Fiorella Biasi University of Turin
Hermann Esterbauer
Hermann Esterbauer University of Graz
Giorgio Bellomo
Giorgio Bellomo University of Milan
Vito Michele Fazio
Vito Michele Fazio Università Campus Bio-Medico
Paolo Pani
Paolo Pani Sapienza University of Rome
Gabriella Leonarduzzi
Gabriella Leonarduzzi University of Turin
Massimo Pinzani
Massimo Pinzani The Royal Free Hospital
Fabio Marra
Fabio Marra University of Florence

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Best Scientists Citing Mario U. Dianzani