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Biology and Biochemistry

D-Index
76
Citations
26493
World Ranking
4966
National Ranking
2385

Overview

Loren J. Field is affiliated with Indiana University in the United States and has contributed extensively to the fields of Medicine as well as Biochemistry, Genetics, and Molecular Biology. Their research primarily focuses on cardiology and cardiovascular medicine, with significant work in molecular biology. Additional subfields include epidemiology, physiology, and aging.

The scientist's work covers various topics related to cardiac health and molecular function, including:

  • Cardiac Fibrosis and Remodeling
  • Cardiomyopathy and Myosin Studies
  • Congenital heart defects research
  • Mitochondrial Function and Pathology
  • Ion channel regulation and function
  • Autophagy in Disease and Therapy
  • Nitric Oxide and Endothelin Effects

Loren J. Field has published in several scientific venues, with frequent contributions to:

  • Circulation
  • Science
  • eLife
  • Biophysical Journal
  • PLoS ONE

Some recent papers authored or co-authored by Field include:

  • Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase (2022, Science)
  • A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8 (2022, eLife)
  • Cardiac Troponin I-Interacting Kinase Affects Cardiomyocyte S-Phase Activity but Not Cardiomyocyte Proliferation (2022, Circulation)
  • Complex Arrhythmia Syndrome in a Knock-In Mouse Model Carrier of the N98S Calm1 Mutation (2020, Circulation)
  • Genetic ablation of Cullin-RING E3 ubiquitin ligase 7 restrains pressure overload-induced myocardial fibrosis (2020, PLoS ONE)

Frequent co-authors collaborating with Loren J. Field include:

  • Kai C. Wollert
  • Kirill V. Tarasov
  • Khalid Chakir
  • Daniel R. Riordon
  • Alexey E. Lyashkov

Best Publications

  • Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts

    Charles E. Murry;Mark H. Soonpaa;Hans Reinecke;Hidehiro Nakajima

  • Human cardiovascular progenitor cells develop from a KDR + embryonic-stem-cell-derived population

    Lei Yang;Mark H. Soonpaa;Eric D. Adler;Torsten K. Roepke

  • Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts.

    Michael G. Klug;Mark H. Soonpaa;Gou Young Koh;Gou Young Koh;Loren J. Field

  • Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy

    Howard A. Rockman;Robert S. Ross;Adrienne N. Harris;Kirk U. Knowlton

  • Cardiomyocyte DNA synthesis and binucleation during murine development

    Mark H. Soonpaa;Kyung Keun Kim;Laura Pajak;Michael Franklin

  • Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium

    Mark H. Soonpaa;Gou Young Koh;Michael G. Klug;Loren J. Field

  • Survey of studies examining mammalian cardiomyocyte DNA synthesis

    Mark H. Soonpaa;Loren J. Field

  • Increased Vulnerability to Atrial Fibrillation in Transgenic Mice With Selective Atrial Fibrosis Caused by Overexpression of TGF-β1

    Sander Verheule;Toshiaki Sato;Thomas Everett;Steven K. Engle

  • Cardiomyocyte Cell Cycle Regulation

    Kishore B.S. Pasumarthi;Loren J. Field

  • Cell-Based Cardiac Repair Reflections at the 10-Year Point

    Charles E. Murry;Loren J. Field;Philippe Menasché

  • Differentiation and long-term survival of C2C12 myoblast grafts in heart.

    Gou Young Koh;Michael G. Klug;Mark H. Soonpaa;Loren J. Field

  • Cardiomyocyte regeneration: A consensus statement

    Thomas Eschenhagen;Roberto Bolli;Thomas Braun;Loren J. Field

  • Assessment of cardiomyocyte DNA synthesis in normal and injured adult mouse hearts

    Mark H. Soonpaa;Loren J. Field

  • Atrial natriuretic factor-SV40 T antigen transgenes produce tumors and cardiac arrhythmias in mice

    Loren J. Field

  • Hypotension in transgenic mice expressing atrial natriuretic factor fusion genes.

    Mark E. Steinhelper;Karen L. Cochrane;Loren J. Field

  • Periostin Is Required for Maturation and Extracellular Matrix Stabilization of Noncardiomyocyte Lineages of the Heart

    Paige Snider;Robert B. Hinton;Ricardo A. Moreno-Rodriguez;Jian Wang

  • Targeted Expression of Cyclin D2 Results in Cardiomyocyte DNA Synthesis and Infarct Regression in Transgenic Mice

    Kishore B.S. Pasumarthi;Hidehiro Nakajima;Hisako O. Nakajima;Mark H. Soonpaa

  • Cyclin D1 overexpression promotes cardiomyocyte DNA synthesis and multinucleation in transgenic mice.

    Mark H. Soonpaa;Gou Young Koh;Gou Young Koh;Laura Pajak;Shaoliang Jing

  • Differential Cardiac Remodeling in Preload Versus Afterload

    Karl Toischer;Adam G. Rokita;Bernhard Unsöld;Wuqiang Zhu

  • Corrections and Retraction: Segregation of Atrial-Specific and Inducible Expression of an Atrial Natriuretic Factor Transgene in an In vivo Murine Model of Cardiac Hypertrophy

    Howard A. Rockman;Robert S. Ross;Adrienne N. Harris;Kirk U. Knowlton

Frequent Co-Authors

Peng-Sheng Chen
Peng-Sheng Chen Cedars-Sinai Medical Center
Adil Daud
Adil Daud University of California, San Francisco
Charles E. Murry
Charles E. Murry University of Washington
Pieter A. Doevendans
Pieter A. Doevendans Utrecht University
Howard A. Rockman
Howard A. Rockman Duke University
Gerd Hasenfuss
Gerd Hasenfuss University of Göttingen
Wolfgang A. Linke
Wolfgang A. Linke University of Münster
Edward F. Srour
Edward F. Srour Indiana University
Kenneth R. Chien
Kenneth R. Chien Karolinska Institute
Gordon Keller
Gordon Keller University of Toronto

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