World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
71
Citations
17579
World Ranking
2415
National Ranking
81

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Pathology
  • Neuroscience

His primary scientific interests are in Internal medicine, Putamen, Caudate nucleus, Dopamine and Pathology. His study in Internal medicine focuses on Dopamine receptor D2 and Raclopride. His biological study spans a wide range of topics, including Dopaminergic, Parkinson's disease and Striatum.

His Dopamine study results in a more complete grasp of Endocrinology. His Endocrinology study integrates concerns from other disciplines, such as Frontal lobe and Apparent oxygen utilisation. His studies deal with areas such as Positron emission tomography, Multiple sclerosis, Blood flow and Blood volume as well as Pathology.

His most cited work include:

  • Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: A study with positron emission tomography and [11C]raclopride (179 citations)
  • Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: A study with positron emission tomography and [11C]raclopride (179 citations)
  • Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: A study with positron emission tomography and [11C]raclopride (179 citations)

What are the main themes of his work throughout his whole career to date?

K. L. Leenders focuses on Internal medicine, Positron emission tomography, Pathology, Endocrinology and Putamen. His Internal medicine and Central nervous system disease, Dopamine receptor D2, Raclopride, Parkinson's disease and Central nervous system investigations all form part of his Internal medicine research activities. His studies in Positron emission tomography integrate themes in fields like Ictal, Blood flow, Blood–brain barrier and Meningioma.

His Degenerative disease and Brain tumor study in the realm of Pathology interacts with subjects such as Distribution Volume. His study in Putamen is interdisciplinary in nature, drawing from both Levodopa, Caudate nucleus and Substantia nigra, Dopaminergic. His Caudate nucleus research includes themes of Basal ganglia and Striatum, Dopamine.

He most often published in these fields:

  • Internal medicine (51.19%)
  • Positron emission tomography (38.10%)
  • Pathology (27.38%)

What were the highlights of his more recent work (between 1998-2009)?

  • Central nervous system disease (22.62%)
  • Positron emission tomography (38.10%)
  • Nuclear medicine (20.24%)

In recent papers he was focusing on the following fields of study:

K. L. Leenders spends much of his time researching Central nervous system disease, Positron emission tomography, Nuclear medicine, Neuroscience and Putamen. His study with Central nervous system disease involves better knowledge in Internal medicine. The Internal medicine study combines topics in areas such as Gastroenterology and Endocrinology.

The study incorporates disciplines such as Pharmacokinetics, Washout, Blood plasma and Meningioma in addition to Positron emission tomography. His work in Putamen is not limited to one particular discipline; it also encompasses Levodopa. His work deals with themes such as Associative learning, Verbal fluency test, Trail Making Test and Raclopride, which intersect with Caudate nucleus.

Between 1998 and 2009, his most popular works were:

  • Metabolic Network Abnormalities in Early Huntington’s Disease: An [18F]FDG PET Study (146 citations)
  • Reproducibility of regional metabolic covariance patterns: comparison of four populations. (107 citations)
  • Imaging Brain Tumor Proliferative Activity with [124I]Iododeoxyuridine (93 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Neuroscience
  • Pathology

Nuclear medicine, Neuroscience, Positron emission tomography, Huntington's disease and Central nervous system disease are his primary areas of study. His Nuclear medicine research is multidisciplinary, relying on both Pharmacokinetics, Washout, Blood plasma and Meningioma. His research in Striatum, Medial frontal gyrus, Midbrain and Limbic lobe are components of Neuroscience.

His Positron emission tomography research incorporates elements of Internal medicine, Disease, Pathology and Metabolic network. His studies in Huntington's disease integrate themes in fields like Caudate nucleus, Basal ganglia, Verbal fluency test and Raclopride. His Central nervous system disease research is multidisciplinary, incorporating elements of Fluorodeoxyglucose, Brain network and Cohort.

Best Publications

  • Cerebral blood flow, blood volume and oxygen utilization. Normal values and effect of age.

    K. L. Leenders;D. Perani;A. A. Lammertsma;J. D. Heather

  • Blood-brain barrier dysfunction in parkinsonian midbrain in vivo.

    Rudie Kortekaas;Klaus L. Leenders;Joost C. H. van Oostrom;Willem Vaalburg

  • EVALUATION OF CEREBRAL PERFUSION RESERVE IN PATIENTS WITH CAROTID-ARTERY OCCLUSION

    J.M Gibbs;K.L Leenders;R.J.S Wise;T Jones

  • The Nigrostriatal Dopaminergic System Assessed in Vivo by Positron Emission Tomography in Healthy Volunteer Subjects and Patients With Parkinson's Disease

    K. L. Leenders;E. P. Salmon;P. Tyrrell;D. Perani

  • Differential psychopathology and patterns of cerebral glucose utilisation produced by (S)- and (R)-ketamine in healthy volunteers using positron emission tomography (PET)

    F.X. Vollenweider;K.L. Leenders;I. Øye;D. Hell

  • Metabolic hyperfrontality and psychopathology in the ketamine model of psychosis using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG).

    F.X Vollenweider;K.L Leenders;C Scharfetter;A Antonini

  • Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

    A. Antonini;K. L. Leenders;R. Spiegel;D. Meier

  • THE RELATIONSHIP BETWEEN LOCOMOTOR DISABILITY, AUTONOMIC DYSFUNCTION, AND THE INTEGRITY OF THE STRIATAL DOPAMINERGIC SYSTEM IN PATIENTS WITH MULTIPLE SYSTEM ATROPHY, PURE AUTONOMIC FAILURE, AND PARKINSON'S DISEASE, STUDIED WITH PET

    D. J. Brooks;E. P. Salmon;C. J. Mathias;N. Quinn

  • Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease

    A Antonini;K L Leenders;P Vontobel;R P Maguire

  • How does the human brain deal with a spinal cord injury

    M. Bruehlmeier;V. Dietz;K. L. Leenders;U. Roelcke

  • Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: a study with positron emission tomography and [11C]raclopride.

    Angelo Antonini;Johannes Schwarz;Wolfgang H. Oertel;Oliver Pogarell

  • Transplantation of fetal dopamine neurons in Parkinson's disease: PET {18F}6‐L‐fluorodopa studies in two patients with putaminal implants

    Sawle Gv;Bloomfield Pm;Björklund A;Brooks Dj

  • Parkinson's disease: the syndrome, the pathogenesis and pathophysiology.

    Anna L. Bartels;Klaus L. Leenders

  • [11C]raclopride and positron emission tomography in previously untreated patients with Parkinson's disease Influence of L‐dopa and lisuride therapy on striatal dopamine D2‐receptors

    A. Antonini;J. Schwarz;W. H. Oertel;H. F. Beer

  • T2 relaxation time in patients with Parkinson's disease

    A. Antonini;K. L. Leenders;D. Meier;W. H. Oertel

  • Complementary positron emission tomographic studies of the striatal dopaminergic system in Parkinson's disease.

    Angelo Antonini;Peter Vontobel;Maria Psylla;Ilonka Günther

  • Metabolic Network Abnormalities in Early Huntington’s Disease: An [18F]FDG PET Study

    Andrew Feigin;Klaus L. Leenders;James R. Moeller;John Missimer

  • Alterations of regional cerebral blood flow and oxygen metabolism in Parkinson's disease.

    Leslie I. Wolfson;Klaus L. Leenders;Lucy L. Brown;Terry Jones

  • Blood-brain barrier P-glycoprotein function decreases in specific brain regions with aging: A possible role in progressive neurodegeneration

    Anna L. Bartels;Rudie Kortekaas;Joost Bart;Antoon T.M. Willemsen

  • Mesiobasal versus lateral temporal lobe epilepsy : metabolic differences in the temporal lobe shown by interictal 18F-FDG positron emission tomography

    Marketa Hajek;Angelo Antonini;Klaus Leonhard Leenders;Heinz Gregor Wieser

  • Studies on regional cerebral oxygen utilisation and cognitive function in multiple sclerosis.

    D J Brooks;K L Leenders;G Head;J Marshall

  • Brain energy metabolism and dopaminergic function in Huntington's disease measured in vivo using positron emission tomography.

    K. L. Leenders;R. S. J. Frackowiak;N. Quinn;C. D. Marsden

  • Pure amnesia after unilateral left polar thalamic infarct: topographic and sequential neuropsychological and metabolic (PET) correlations.

    S Clarke;G Assal;J Bogousslavsky;F Regli

  • Familial parkinsonism with synuclein pathology Clinical and PET studies of A30P mutation carriers

    Rejko Krüger;W. Kuhn;K. L. Leenders;R. Sprengelmeyer

  • Correction for the presence of intravascular oxygen-15 in the steady-state technique for measuring regional oxygen extraction ratio in the brain: 2. Results in normal subjects and brain tumour and stroke patients.

    Adriaan A. Lammertsma;Richard J. S. Wise;Jon D. Heather;Jeremy M. Gibbs

  • In vivo evaluation of striatal dopamine reuptake sites using 11C-nomifensine and positron emission tomography

    S.-M. Aquilonius;K. Bertröm;S-Å. Eckernäs;P. Hartvig

  • [11C]Raclopride‐PET studies of the Huntington's disease rate of progression: Relevance of the trinucleotide repeat length

    Angelo Antonini;Klaus L. Leenders;Klaus L. Leenders;David Eidelberg

  • Intermanual transfer of proximal and distal motor engrams in humans

    Gregor Thut;Gregor Thut;Norman D. Cook;Marianne Regard;Klaus L. Leenders;Klaus L. Leenders

  • Reduced glucose metabolism in the frontal cortex and basal ganglia of multiple sclerosis patients with fatigue: A F-18-fluorodeoxyglucose positron emission tomography study

    U Roelcke;L Kappos;J LechnerScott;H Brunnschweiler

Frequent Co-Authors

David J. Brooks
David J. Brooks Newcastle University
Gregor Thut
Gregor Thut Centre national de la recherche scientifique, CNRS
Marianne Regard
Marianne Regard University of Zurich
Heinz Gregor Wieser
Heinz Gregor Wieser University of Zurich
Håkan Widner
Håkan Widner Lund University
Charles David Marsden
Charles David Marsden King's College London
Anders Björklund
Anders Björklund Lund University
Johannes Schwarz
Johannes Schwarz Leipzig University
David Eidelberg
David Eidelberg Feinstein Institute for Medical Research
Theodor Landis
Theodor Landis University of Geneva

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Klaus L. Leenders

Trending Scientists