What is he best known for?
The fields of study he is best known for:
- Enzyme
- Amino acid
- Biochemistry
John E. Folk spends much of his time researching Biochemistry, Hypusine, Deoxyhypusine synthase, EIF5A and Deoxyhypusine Hydroxylase.
John E. Folk regularly ties together related areas like Guinea pig in his Biochemistry studies.
His EIF5A research integrates issues from Spermidine, Polyamine and Protein biosynthesis.
His work in Spermidine tackles topics such as Binding site which are related to areas like Stereochemistry.
Deoxyhypusine Hydroxylase and Amino acid are two areas of study in which John E. Folk engages in interdisciplinary research.
His Tissue transglutaminase research focuses on Chromatography and how it connects with Amino acid composition, Peptide and Polyacrylamide gel electrophoresis.
His most cited work include:
- Carboxypeptidase B IV. PURIFICATION AND CHARACTERIZATION OF THE PORCINE ENZYME (405 citations)
- THE PORCINE PANCREATIC CARBOXYPEPTIDASE A SYSTEM. I. THREE FORMS OF THE ACTIVE ENZYME. (315 citations)
- Mechanism of Action of Guinea Pig Liver Transglutaminase I. PURIFICATION AND PROPERTIES OF THE ENZYME: IDENTIFICATION OF A FUNCTIONAL CYSTEINE ESSENTIAL FOR ACTIVITY (243 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, Stereochemistry, Enzyme, Hypusine and Lysine.
John E. Folk conducted interdisciplinary study in his works that combined Biochemistry and Deoxyhypusine synthase.
His work carried out in the field of Stereochemistry brings together such families of science as Amide, Active site, Hydrolysis, Substrate and Binding site.
His study in Enzyme is interdisciplinary in nature, drawing from both Glutamine, In vitro and Peptide.
His Lysine study combines topics from a wide range of disciplines, such as Proteolysis, Moiety and Biosynthesis.
The Amino acid study combines topics in areas such as Chromatography, Proteolytic enzymes and Chymotrypsin.
He most often published in these fields:
- Biochemistry (57.85%)
- Stereochemistry (26.45%)
- Enzyme (27.27%)
What were the highlights of his more recent work (between 2005-2012)?
- Pharmacology (11.57%)
- Agonist (14.05%)
- δ-opioid receptor (6.61%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Pharmacology, Agonist, δ-opioid receptor, Endocrinology and Internal medicine.
His research investigates the connection between Pharmacology and topics such as Opioid that intersect with problems in Morphine and Mechanism of action.
His study focuses on the intersection of Agonist and fields such as Nociception with connections in the field of Methadone.
John E. Folk studied δ-opioid receptor and Stimulation that intersect with Delta opioid agonist, Amphetamine and Nociceptor.
John E. Folk interconnects Monoamine transporter and Opioid peptide in the investigation of issues within Endocrinology.
Particularly relevant to Enzyme is his body of work in Biochemistry.
Between 2005 and 2012, his most popular works were:
- Nε-(γ-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with huntington's disease (75 citations)
- The Convulsive and Electroencephalographic Changes Produced by Nonpeptidic δ-Opioid Agonists in Rats: Comparison with Pentylenetetrazol (67 citations)
- Increased Levels of γ-glutamylamines in Huntington disease CSF (50 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Amino acid
- Biochemistry
His main research concerns Biochemistry, Pharmacology, Enzyme, Lysine and In vitro.
Many of his studies involve connections with topics such as Thrombin and Biochemistry.
His research integrates issues of Convulsant and Opioid in his study of Pharmacology.
In the field of Enzyme, his study on Putrescine and Proteolysis overlaps with subjects such as Huntingtin Protein and Huntington's disease.
His biological study spans a wide range of topics, including Tissue transglutaminase, Molecular biology and Cerebrospinal fluid.
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