Jean-Luc Moreau

Best Publications

• Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress.

  Francois Jenck;Jean-Luc Moreau;James R. Martin;Gavin J. Kilpatrick

  453
  Citations

• 5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential.

  J. R. Martin;M. Bös;F. Jenck;J.-L. Moreau

  435
  Citations

• TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity.

  Florent G. Revel;Jean-Luc Moreau;Raul R. Gainetdinov;Amyaouch Bradaia

  373
  Citations

• Trace Amine-Associated Receptor 1 Modulates Dopaminergic Activity

  Lothar Lindemann;Claas Aiko Meyer;Karine Jeanneau;Amyaouch Bradaia

  364
  Citations

• A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: Anxiolytic profile in the rat

  François Jenck;Juergen Wichmann;Frank M. Dautzenberg;Jean-Luc Moreau

  348
  Citations

• Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission.

  Jean-Luc Moreau;Howard L. Fields

  329
  Citations

• Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice

  Anja Köster;Alexandra Montkowski;Stefan Schulz;Eva-Maria Stübe

  300
  Citations

• Antidepressant treatment prevents chronic unpredictable mild stress-induced anhedonia as assessed by ventral tegmentum self-stimulation behavior in rats

  J.-L. Moreau;F. Jenck;J.R. Martin;P. Mortas

  299
  Citations

• Enhanced long-term synaptic depression in an animal model of depression.

  Roman Holderbach;Kristin Clark;Jean-Luc Moreau;Josef Bischofberger

  250
  Citations

• Decreased hedonic responsiveness following chronic mild stress is not secondary to loss of body weight

  Paul Willner;Jean-Luc Moreau;Christina Kurre Nielsen;Mariusz Papp

  245
  Citations

• Central adenosine A2A receptors: an overview

  Jean-Luc Moreau;Gerda Huber

  210
  Citations

• Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia.

  Emmanuel Pinard;Alexander Alanine;Daniela Alberati;Markus Bender

  209
  Citations

• RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors

  Theresa M. Ballard;Frédéric Knoflach;Eric Prinssen;Edilio Borroni

  207
  Citations

• Urocortin, a novel neuropeptide with anxiogenic-like properties.

  Jean-Luc Moreau;Gavin Kilpatrick;François Jenck

  198
  Citations

• Trace Amine-Associated Receptor 1 Partial Agonism Reveals Novel Paradigm for Neuropsychiatric Therapeutics

  Florent G. Revel;Jean-Luc Moreau;Raul R. Gainetdinov;Antonio Ferragud

  190
  Citations

• Hippocampal low-frequency stimulation and chronic mild stress similarly disrupt fear extinction memory in rats.

  René Garcia;Guillaume Spennato;Linda Nilsson-Todd;Jean-Luc Moreau

  174
  Citations

• Novel agonists of 5HT2C receptors. Synthesis and biological evaluation of substituted 2-(indol-1-yl)-1-methylethylamines and 2-(indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved therapeutics for obsessive compulsive disorder.

  Michael Bös;François Jenck;James R. Martin;Jean-Luc Moreau

  172
  Citations

• Molecular biology of the CRH receptors-- in the mood.

  Frank M Dautzenberg;Gavin J Kilpatrick;Richard L Hauger;Jean-Luc Moreau

  171
  Citations

• 5HT2C receptor agonists exhibit antidepressant-like properties in the anhedonia model of depression in rats.

  J.-L. Moreau;M. Bös;F. Jenck;J.R. Martin

  169
  Citations

• Some critical determinants of the behaviour of rats in the elevated plus-maze

  Guy Griebel;Jean-Luc Moreau;François Jenck;James R. Martin

  167
  Citations