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Neuroscience

D-Index
48
Citations
7345
World Ranking
6252
National Ranking
361

Overview

James A. Sharpe was affiliated with the University Health Network in Canada. Their research primarily focused on the intersection of biochemistry, genetics, and molecular biology, with extensive contributions also in medicine.

The main research fields included:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Sharpe's work was detailed through various subfields of study such as molecular biology, public health, environmental and occupational health, genetics, immunology, and biophysics.

  • Molecular Biology
  • Public Health, Environmental and Occupational Health
  • Genetics
  • Immunology
  • Biophysics

The researcher explored topics spanning developmental biology and gene regulation, single-cell and spatial transcriptomics, pluripotent stem cells research, cellular mechanics and interactions, cell image analysis techniques, Down syndrome and intellectual disability research, and congenital heart defects research.

  • Developmental Biology and Gene Regulation
  • Single-cell and Spatial Transcriptomics
  • Pluripotent Stem Cells Research
  • Cellular Mechanics and Interactions
  • Cell Image Analysis Techniques
  • Down Syndrome and Intellectual Disability Research
  • Congenital Heart Defects Research

Their frequently published research appeared in several venues, with the highest number of publications in bioRxiv (Cold Spring Harbor Laboratory), followed by Nature Communications and Development. Other notable venues included arXiv (Cornell University) and The FASEB Journal.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Development
  • arXiv (Cornell University)
  • The FASEB Journal

Frequent coauthors in Sharpe's collaborative work included Fumio Nakaki, Neus Martínez-Abadías, Nicola Gritti, Vikas Trivedi, and Marco Musy.

  • Fumio Nakaki
  • Neus Martínez-Abadías
  • Nicola Gritti
  • Vikas Trivedi
  • Marco Musy

Among recent publications, key papers comprised:

  • "Periodic formation of epithelial somites from human pluripotent stem cells," 2022, Nature Communications
  • "Salivary gland macrophages and tissue-resident CD8 + T cells cooperate for homeostatic organ surveillance," 2020, Science Immunology
  • "Topologically selective islet vulnerability and self-sustained downregulation of markers for β-cell maturity in streptozotocin-induced diabetes," 2020, Communications Biology
  • "Arrested coalescence of multicellular aggregates," 2022, Soft Matter
  • "Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome," 2021, Scientific Reports

Best Publications

  • Ocular motor deficits in Parkinson's disease. II. Control of the saccadic and smooth pursuit systems.

    O B White;J A Saint-Cyr;R D Tomlinson;J A Sharpe

  • Saccadic eye movement dysfunction in Alzheimer's disease.

    William A. Fletcher;James A. Sharpe

  • Effect of aging on horizontal smooth pursuit.

    James A. Sharpe;Trevor O. Sylvester

  • Ocular motor deficits in Parkinson's disease. III. Coordination of eye and head movements.

    Owen B. White;Jean A. Saint-Cyr;R. David Tomlinson;James A. Sharpe

  • CONTROL OF THE SACCADIC AND SMOOTH PURSUIT SYSTEMS AFTER CEREBRAL HEMIDECORTICATION

    James A. Sharpe;Alex W. Lo;Hyman E. Rabinovitch

  • Opsoclonus in three dimensions: oculographic, neuropathologic and modelling correlates

    Agnes M.F Wong;Sam Musallam;R.D Tomlinson;Patrick Shannon

  • Visual processing of motion-defined form: selective failure in patients with parietotemporal lesions

    D Regan;D Giaschi;JA Sharpe;XH Hong

  • Smooth pursuit dysfunction in Alzheimer's disease.

    William A. Fletcher;James A. Sharpe

  • Progressive ataxia and palatal tremor (PAPT) Clinical and MRI assessment with review of palatal tremors

    Michael Samuel;Michael Samuel;Nurhan Torun;Nurhan Torun;Paul J. Tuite;James A. Sharpe

  • Cerebral and retinal vascular complications of inflammatory bowel disease

    Jacob H. Schneiderman;Jacob H. Schneiderman;James A. Sharpe;James A. Sharpe;David M. C. Sutton;David M. C. Sutton

  • Senescent saccades. Effects of aging on their accuracy, latency and velocity.

    James A. Sharpe;David H. Zackon

  • Palsy of upward and downward saccadic, pursuit, and vestibular movements with a unilateral midbrain lesion: pathophysiologic correlations.

    Paul J. Ranalli;James A. Sharpe;William A. Fletcher

  • Paralytic pontine exotropia: A sign of acute unilateral pontine gaze palsy and internuclear ophthalmoplegia

    James A. Sharpe;Michael A. Rosenberg;William F. Hoyt;Robert B. Daroff

  • Cerebral hemispheric localization of smooth pursuit asymmetry.

    Mark J. Morrow;James A. Sharpe

  • Vertical vestibulo-ocular reflex, smooth pursuit and eye-head tracking dysfunction in internuclear ophthalmoplegia.

    Paul J. Ranalli;James A. Sharpe

  • Torsional nystagmus in the lateral medullary syndrome

    Marchk J. Morrow;James A. Sharpe

  • Saccades in children

    Michael S. Salman;James A. Sharpe;Moshe Eizenman;Linda Lillakas

  • Methanol optic neuropathy

    Unknown

  • Cerebral square wave jerks

    James A. Sharpe;Yuval O. Herishanu;Owen B. White

  • Neurophysiology and neuroanatomy of smooth pursuit: Lesion studies

    James A. Sharpe

  • The Ocular Tilt Reaction: A Paroxysmal Dyskinesia Associated With Elliptical Nystagmus

    Hyman E. Rabinovitch;James A. Sharpe;Trevor O. Sylvester

  • Ocular motor paresis versus apraxia

    James A. Sharpe;Janine L. Johnston

Frequent Co-Authors

Maureen Dennis
Maureen Dennis University of Toronto
Jason J. S. Barton
Jason J. S. Barton University of British Columbia
William D. Hutchison
William D. Hutchison University of Toronto
Andres M. Lozano
Andres M. Lozano University of Toronto
Jean A. Saint-Cyr
Jean A. Saint-Cyr University of Toronto
Jane E. Raymond
Jane E. Raymond University of Birmingham
Jonathan O. Dostrovsky
Jonathan O. Dostrovsky University of Toronto
Elena Moro
Elena Moro Grenoble Alpes University
Richard Wennberg
Richard Wennberg University Health Network
Richard Leigh
Richard Leigh National Institutes of Health

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