Harri Lähdesmäki

Overview

Best Publications

• Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

  Tommi Vatanen;Tommi Vatanen;Aleksandar D. Kostic;Aleksandar D. Kostic;Eva D'Hennezel;Heli Siljander

  1379
  Citations

• The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

  Aleksandar D. Kostic;Aleksandar D. Kostic;Dirk Gevers;Heli Siljander;Tommi Vatanen;Tommi Vatanen

  1296
  Citations

• The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

  Tommi Vatanen;Eric A. Franzosa;Eric A. Franzosa;Randall Schwager;Surya Tripathi

  869
  Citations

• The Transcription Factor NFAT Promotes Exhaustion of Activated CD8+ T Cells

  Gustavo J. Martinez;Renata M. Pereira;Tarmo Äijö;Tarmo Äijö;Edward Y. Kim

  856
  Citations

• Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX

  Myunggon Ko;Jungeun An;Hozefa S. Bandukwala;Lukas Chavez

  409
  Citations

• On Learning Gene Regulatory Networks Under the Boolean Network Model

  Harri Lähdesmäki;Ilya Shmulevich;Olli Yli-Harja

  364
  Citations

• Control of Foxp3 stability through modulation of TET activity.

  Xiaojing Yue;Sara Trifari;Tarmo Äijö;Tarmo Äijö;Ageliki Tsagaratou

  337
  Citations

• Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer

  S E Jalava;A Urbanucci;L Latonen;K K Waltering

  253
  Citations

• Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis.

  Xishan Hao;Baocun Sun;Limei Hu;Harri Lähdesmäki;Harri Lähdesmäki

  239
  Citations

• Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life.

  Tommi Vatanen;Damian R. Plichta;Juhi Somani;Philipp C. Münch

  234
  Citations

• Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility

  Henna Kallionpaa;Laura L. Elo;Essi Laajala;Juha Mykkanen

  201
  Citations

• Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1–BAP1 complex

  Anand Balasubramani;Antti Larjo;Jed A. Bassein;Xing Chang

  196
  Citations

• The role of certain Post classes in Boolean network models of genetic networks

  Ilya Shmulevich;Harri Lähdesmäki;Harri Lähdesmäki;Edward R. Dougherty;Jaakko Astola

  188
  Citations

• Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming.

  Laura L. Elo;Henna Järvenpää;Soile Tuomela;Sunil Raghav

  183
  Citations

• Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer.

  A. Urbanucci;B. Sahu;J. Seppälä;A. Larjo

  175
  Citations

• Robust detection of periodic time series measured from biological systems.

  Miika Ahdesmäki;Harri Lähdesmäki;Ronald K. Pearson;Heikki Huttunen

  164
  Citations

• Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation

  Ageliki Tsagaratou;Tarmo Äijö;Chan-Wang J. Lio;Xiaojing Yue

  164
  Citations

• Relationships between probabilistic Boolean networks and dynamic Bayesian networks as models of gene regulatory networks

  Harri Lähdesmäki;Sampsa Hautaniemi;Ilya Shmulevich;Olli Yli-Harja

  143
  Citations

• Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub

  Romain Roncagalli;Simon Hauri;Fréderic Fiore;Fréderic Fiore;Fréderic Fiore;Yinming Liang;Yinming Liang;Yinming Liang

  140
  Citations

• Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

  Tommi Vatanen;Damian R. Plichta;Juhi Somani;Philipp C. Muench

  0
  Citations