Edze R. Westra

Best Publications

• Unravelling the structural and mechanistic basis of CRISPR-Cas systems.

  John van der Oost;Edze R. Westra;Edze R. Westra;Ryan N. Jackson;Blake Wiedenheft

  8474
  Citations

• Small CRISPR RNAs guide antiviral defense in prokaryotes

  Stan J. J. Brouns;Matthijs M. Jore;Magnus Lundgren;Edze R. Westra

  3377
  Citations

• Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

  Ekaterina Semenova;Matthijs M. Jore;Kirill A. Datsenko;Anna Semenova

  1043
  Citations

• Structural basis for CRISPR RNA-guided DNA recognition by Cascade

  Matthijs M Jore;Magnus Lundgren;Magnus Lundgren;Esther van Duijn;Jelle B Bultema

  712
  Citations

• CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

  Edze R. Westra;Paul B.G. van Erp;Tim Künne;Shi Pey Wong

  711
  Citations

• CRISPR-based adaptive and heritable immunity in prokaryotes.

  John van der Oost;Matthijs M. Jore;Edze R. Westra;Magnus Lundgren

  700
  Citations

• Interactions between bacterial and phage communities in natural environments.

  Unknown

  643
  Citations

• Dna-guided dna interference by a prokaryotic argonaute

  Der Oost John Van;Daniël Christianus Swarts;Andrew Paul May;Rachel E. Haurwitz

  565
  Citations

• Prophages mediate defense against phage infection through diverse mechanisms

  Joseph Bondy-Denomy;Jason Qian;Edze R Westra;Angus Buckling

  534
  Citations

• CRISPR–Cas systems: beyond adaptive immunity

  Edze R. Westra;Angus Buckling;Peter C. Fineran

  387
  Citations

• The CRISPRs, They Are A-Changin': How Prokaryotes Generate Adaptive Immunity

  Edze R Westra;Daan C Swarts;Raymond H J Staals;Matthijs M Jore

  387
  Citations

• Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system.

  Nina M Høyland-Kroghsbo;Jon Paczkowski;Sampriti Mukherjee;Jenny Broniewski

  332
  Citations

• Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli

  Ryan N. Jackson;Sarah M. Golden;Paul B. G. van Erp;Joshua Carter

  328
  Citations

• H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO

  Edze R. Westra;Ümit Pul;Nadja Heidrich;Matthijs M. Jore

  309
  Citations

• Parasite Exposure Drives Selective Evolution of Constitutive versus Inducible Defense

  Edze R. Westra;Stineke van Houte;Sam Oyesiku-Blakemore;Ben Makin

  295
  Citations

• Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition.

  Edze R. Westra;Ekaterina Semenova;Kirill A. Datsenko;Ryan N. Jackson

  294
  Citations

• The diversity-generating benefits of a prokaryotic adaptive immune system

  Stineke van Houte;Alice K. E. Ekroth;Jenny M. Broniewski;Hélène Chabas;Hélène Chabas

  290
  Citations

• Evolutionary Ecology of Prokaryotic Immune Mechanisms

  Stineke van Houte;Angus Buckling;Edze R. Westra

  271
  Citations

• Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity

  Mariann Landsberger;Sylvain Gandon;Sean Meaden;Clare Rollie

  243
  Citations

• Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes

  Al-Attar S;Westra Er;van der Oost J;Brouns Sj

  217
  Citations