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Neuroscience

D-Index
34
Citations
4543
World Ranking
9344
National Ranking
3947

Overview

Don Shin is affiliated with the University of California, Los Angeles in the United States. Their research primarily focuses on the intersection of medicine, biochemistry, genetics and molecular biology, and neuroscience, with a significant emphasis on gut microbiota and its relationship to health.

The topics frequently explored in their work include:

  • Gut microbiota and health
  • Barrier structure and function studies
  • Immune response and inflammation
  • Diet and metabolism studies
  • Pharmacological effects and toxicity studies
  • Clostridium difficile and Clostridium perfringens research
  • Gastrointestinal motility and disorders

Don Shin has contributed to various subfields such as molecular biology, neurology, immunology, physiology, and pediatrics, perinatology, and child health. Their work appears in a range of publication venues, notably including:

  • Epilepsia
  • Epilepsy & Behavior
  • Epilepsia Open

Among recent papers published, the following stand out with their publication year and venues:

  • Disruption of intestinal barrier and endotoxemia after traumatic brain injury: Implications for post-traumatic epilepsy (2021, Epilepsia)
  • Susceptibility to epilepsy after traumatic brain injury is associated with preexistent gut microbiome profile (2022, Epilepsia)
  • Modification of post-traumatic epilepsy by fecal microbiota transfer (2022, Epilepsy & Behavior)
  • Diversity of kindling of limbic seizures after lateral fluid percussion injury in the rat (2021, Epilepsia Open)

Frequent co-authors collaborating with Don Shin include:

  • Andréy Mazarati
  • Jesús-Servando Medel-Matus
  • Raman Sankar
  • Jonathan P. Jacobs
  • Venu Lagishetty

The integration of disciplines such as molecular biology and neurology, together with their focus on barrier function and immune response, points to a research profile concentrated on understanding complex interactions between the gut microbiome and neurological disorders, particularly in relation to traumatic brain injury and epilepsy.

Best Publications

  • Patterns of Status Epilepticus-Induced Neuronal Injury during Development and Long-Term Consequences

    R. Sankar;D. H. Shin;D. H. Shin;Hantao Liu;A. Mazarati

  • Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine.

    Andréy Mazarati;Prabha Siddarth;Roger A. Baldwin;Don Shin

  • Galanin Modulation of Seizures and Seizure Modulation of Hippocampal Galanin in Animal Models of Status Epilepticus

    Andrey M. Mazarati;Hantao Liu;Ursel Soomets;Ursel Soomets;Raman Sankar

  • Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy

    Andrey M. Mazarati;Don Shin;Young Se Kwon;Young Se Kwon;Anatol Bragin

  • Serum neuron-specific enolase is a marker for neuronal damage following status epilepticus in the rat

    Raman Sankar;Don H Shin;Claude G Wasterlain

  • Epileptogenesis after status epilepticus reflects age- and model-dependent plasticity.

    Raman Sankar;Don Shin;Don Shin;Andrey M. Mazarati;Andrey M. Mazarati;Hantao Liu;Hantao Liu

  • Inflammation induced by LPS enhances epileptogenesis in immature rat and may be partially reversed by IL1RA

    Stéphane Auvin;Don Shin;Andrey Mazarati;Raman Sankar

  • Self-sustaining status epilepticus after brief electrical stimulation of the perforant path.

    Andrey M. Mazarati;Claude G. Wasterlain;Raman Sankar;Don Shin

  • Regulation of Kindling Epileptogenesis by Hippocampal Galanin Type 1 and Type 2 Receptors: The Effects of Subtype-Selective Agonists and the Role of G-Protein-Mediated Signaling

    Andrey Mazarati;Linda Lundstrom;Ulla E Sollenberg;Don Shin

  • Neuronal Glucose Transporter Isoform 3 Deficient Mice Demonstrate Features of Autism Spectrum Disorders

    Yuanzi Zhao;Camille Fung;Don Shin;Bo-Chul Shin

  • Insulin-responsive glucose transporters-GLUT8 and GLUT4 are expressed in the developing mammalian brain

    Raman Sankar;Shanthie Thamotharan;Don Shin;Kelle H Moley

  • Granule Cell Neurogenesis After Status Epilepticus in the Immature Rat Brain

    Raman Sankar;Don Shin;Don Shin;Hantao Liu;Hiroshi Katsumori

  • Bumetanide inhibits rapid kindling in neonatal rats

    Andréy Mazarati;Don Shin;Raman Sankar

  • Comorbidity between epilepsy and depression: experimental evidence for the involvement of serotonergic, glucocorticoid, and neuroinflammatory mechanisms.

    Eduardo Pineda;Don Shin;Raman Sankar;Andrey M. Mazarati

  • Maternal immune activation promotes hippocampal kindling epileptogenesis in mice.

    Eduardo Pineda;Don Shin;Su Jeong You;Su Jeong You;Stéphane Auvin

  • Kindling epileptogenesis in immature rats leads to persistent depressive behavior.

    Andréy Mazarati;Don Shin;Stéphane Auvin;Rochelle Caplan

  • Comorbidity between epilepsy and depression: Role of hippocampal interleukin-1β

    Andre Y. M. Mazarati;Eduardo Pineda;Don Shin;Delia Tio

  • Inflammation exacerbates seizure-induced injury in the immature brain.

    Stéphane Auvin;Don Shin;Andrey Mazarati;JoAnne Nakagawa

  • Inflammation enhances epileptogenesis in the developing rat brain.

    Stéphane Auvin;Andrey Mazarati;Don Shin;Raman Sankar

  • Postnatal hypoxic-ischemic brain injury alters mechanisms mediating neuronal glucose transport

    Ann Zovein;Judy Flowers-Ziegler;Shanthie Thamotharan;Don Shin

Frequent Co-Authors

Raman Sankar
Raman Sankar University of California, Los Angeles
Andrey Mazarati
Andrey Mazarati University of California, Los Angeles
Claude G. Wasterlain
Claude G. Wasterlain University of California, Los Angeles
Stéphane Auvin
Stéphane Auvin Université Paris Cité
Anatol Bragin
Anatol Bragin University of California, Los Angeles
Steven S. Schreiber
Steven S. Schreiber University of California, Irvine
Prabha Siddarth
Prabha Siddarth University of California, Los Angeles
Dan Ehninger
Dan Ehninger German Center for Neurodegenerative Diseases
W. McIntyre Burnham
W. McIntyre Burnham University of Toronto
Christine M. Gall
Christine M. Gall University of California, Irvine

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