Dean C. Crick

Overview

Best Publications

• Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis

  Dean C. Crick;Sebabrata Mahapatra;Patrick J. Brennan

  381
  Citations

• Phosphatidylinositol Is an Essential Phospholipid of Mycobacteria

  Mary Jackson;Dean C. Crick;Patrick J. Brennan

  285
  Citations

• Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways.

  Brian C. VanderVen;Jeffery D. Harder;Dean C. Crick;John T. Belisle

  283
  Citations

• Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

  Kai Li;Lici A. Schurig-Briccio;Xinxin Feng;Ashutosh Upadhyay

  265
  Citations

• Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis

  Wei Li;Ashutosh Upadhyay;Fabio L. Fontes;E. Jeffrey North

  235
  Citations

• Decaprenylphosphoryl arabinofuranose, the donor of the D-arabinofuranosyl residues of mycobacterial arabinan, is formed via a two-step epimerization of decaprenylphosphoryl ribose.

  Katarína Mikušová;Hairong Huang;Tetsuya Yagi;Marcelle Holsters

  235
  Citations

• Identification of the namH Gene, Encoding the Hydroxylase Responsible for the N-Glycolylation of the Mycobacterial Peptidoglycan

  Jon B. Raymond;Sebabrata Mahapatra;Dean C. Crick;Martin S. Pavelka

  216
  Citations

• Unique Mechanism of Action of the Thiourea Drug Isoxyl on Mycobacterium tuberculosis

  Benjawan Phetsuksiri;Mary Jackson;Hataichanok Scherman;Michael R. McNeil

  200
  Citations

• The Cell-Wall Core of Mycobacterium tuberculosis in the Context of Drug Discovery.

  Patrick J Brennan;Dean C Crick

  196
  Citations

• A Phosphorylated Pseudokinase Complex Controls Cell Wall Synthesis in Mycobacteria

  Christine L. Gee;Kadamba G. Papavinasasundaram;Sloane R. Blair;Christina E. Baer

  184
  Citations

• Novel salvage pathway utilizing farnesol and geranylgeraniol for protein isoprenylation.

  Dean C. Crick;Douglas A. Andres;Charles J. Waechter

  170
  Citations

• Antiinfectives targeting enzymes and the proton motive force

  Xinxin Feng;Wei Zhu;Lici A. Schurig-Briccio;Steffen Lindert

  162
  Citations

• Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel "Mtb LipidDB".

  Mark J. Sartain;Donald L. Dick;Christopher D. Rithner;Dean C. Crick

  161
  Citations

• Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence.

  Rakesh K. Dhiman;Sebabrata Mahapatra;Richard A. Slayden;Melissa E. Boyne

  159
  Citations

• Biosynthesis of the galactan component of the mycobacterial cell wall.

  Katarı́na Mikušová;Tetsuya Yagi;Richard Stern;Michael R. McNeil

  153
  Citations

• Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis.

  Sudagar S Gurcha;Alain R Baulard;Laurent Kremer;Camille Locht

  141
  Citations

• Targeting the formation of the cell wall core of M. tuberculosis.

  Clifton E. Barry;Dean C. Crick;Michael R. McNeil

  141
  Citations

• Inhibition of the First Step in Synthesis of the Mycobacterial Cell Wall Core, Catalyzed by the GlcNAc-1-phosphate Transferase WecA, by the Novel Caprazamycin Derivative CPZEN-45

  Yoshimasa Ishizaki;Chigusa Hayashi;Kunio Inoue;Masayuki Igarashi

  133
  Citations

• Discovery of Selective Menaquinone Biosynthesis Inhibitors against Mycobacterium tuberculosis

  Joy Debnath;Shajila Siricilla;Bajoie Wan;Dean C. Crick

  132
  Citations

• MINI REVIEW Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis

  Dean C. Crick;Sebabrata Mahapatra;Patrick J. Brennan

  0
  Citations