D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 7,325 98 World Ranking 7789 National Ranking 3518

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His scientific interests lie mostly in Biochemistry, Mycobacterium tuberculosis, Microbiology, Mycobacterium smegmatis and Enzyme. Dean C. Crick studied Biochemistry and Lipoarabinomannan that intersect with ATP synthase. His biological study spans a wide range of topics, including Glycosylation, Mode of action and Membrane transport protein.

His research integrates issues of Mycobacterium and Bacteria in his study of Microbiology. His work in Mycobacterium smegmatis addresses issues such as Mutant, which are connected to fields such as Transmembrane domain. His Enzyme research incorporates themes from In vitro toxicology and Escherichia coli.

His most cited work include:

  • Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways. (256 citations)
  • Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis (233 citations)
  • Phosphatidylinositol Is an Essential Phospholipid of Mycobacteria (181 citations)

What are the main themes of his work throughout his whole career to date?

Dean C. Crick mostly deals with Biochemistry, Mycobacterium tuberculosis, Microbiology, Biosynthesis and Mycobacterium smegmatis. His research is interdisciplinary, bridging the disciplines of Lipoarabinomannan and Biochemistry. Dean C. Crick works mostly in the field of Mycobacterium tuberculosis, limiting it down to topics relating to ATP synthase and, in certain cases, Erythritol.

His work carried out in the field of Microbiology brings together such families of science as Drug target and Bacteria. As a part of the same scientific study, Dean C. Crick usually deals with the Biosynthesis, concentrating on Prenylation and frequently concerns with Farnesyl pyrophosphate and Geranylgeraniol. His study looks at the intersection of Mycobacterium smegmatis and topics like Mycobacterium with Galactan.

He most often published in these fields:

  • Biochemistry (61.36%)
  • Mycobacterium tuberculosis (37.12%)
  • Microbiology (26.52%)

What were the highlights of his more recent work (between 2015-2021)?

  • Mycobacterium tuberculosis (37.12%)
  • Nuclear magnetic resonance spectroscopy (3.03%)
  • Membrane (2.27%)

In recent papers he was focusing on the following fields of study:

Dean C. Crick spends much of his time researching Mycobacterium tuberculosis, Nuclear magnetic resonance spectroscopy, Membrane, Growth inhibition and Microbiology. His Mycobacterium tuberculosis research integrates issues from In vitro, Biosynthesis, Enzyme, Natural product and Pharmacology. His Membrane research also works with subjects such as

  • Stereochemistry that intertwine with fields like Menadione, Menadiol, Function, Naphthoquinone and Mycobacterium,
  • Micelle which is related to area like Electron acceptor, Molecule, Folding and Two-dimensional nuclear magnetic resonance spectroscopy.

The various areas that Dean C. Crick examines in his Growth inhibition study include Pyrazinamide, Acid–base reaction, Mycobacterium smegmatis, Vanadium and Vanadate. His Mycobacterium smegmatis study combines topics in areas such as Medicinal chemistry, Growth medium, Hydrolysis, Aqueous solution and Monomer. His research in Microbiology focuses on subjects like Gene, which are connected to Bacteria.

Between 2015 and 2021, his most popular works were:

  • Oxidative phosphorylation as a target space for tuberculosis: success, caution, and future directions (41 citations)
  • Decavanadate Inhibits Mycobacterial Growth More Potently Than Other Oxovanadates. (22 citations)
  • Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. (21 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis

Dean C. Crick;Sebabrata Mahapatra;Patrick J. Brennan.
Glycobiology (2001)

353 Citations

Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways.

Brian C. VanderVen;Jeffery D. Harder;Dean C. Crick;John T. Belisle.
Science (2005)

256 Citations

Phosphatidylinositol Is an Essential Phospholipid of Mycobacteria

Mary Jackson;Dean C. Crick;Patrick J. Brennan.
Journal of Biological Chemistry (2000)

245 Citations

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

Kai Li;Lici A. Schurig-Briccio;Xinxin Feng;Ashutosh Upadhyay.
Journal of Medicinal Chemistry (2014)

192 Citations

Decaprenylphosphoryl Arabinofuranose, the Donor of the D-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of Decaprenylphosphoryl Ribose

Katarína Mikušová;Hairong Huang;Tetsuya Yagi;Marcelle Holsters.
Journal of Bacteriology (2005)

190 Citations

The Cell-Wall Core of Mycobacterium tuberculosis in the Context of Drug Discovery.

Patrick J Brennan;Dean C Crick.
Current Topics in Medicinal Chemistry (2007)

179 Citations

Identification of the namH Gene, Encoding the Hydroxylase Responsible for the N-Glycolylation of the Mycobacterial Peptidoglycan

Jon B. Raymond;Sebabrata Mahapatra;Dean C. Crick;Martin S. Pavelka.
Journal of Biological Chemistry (2005)

177 Citations

Unique Mechanism of Action of the Thiourea Drug Isoxyl on Mycobacterium tuberculosis

Benjawan Phetsuksiri;Mary Jackson;Hataichanok Scherman;Michael R. McNeil.
Journal of Biological Chemistry (2003)

171 Citations

Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis

Wei Li;Ashutosh Upadhyay;Fabio L. Fontes;E. Jeffrey North.
Antimicrobial Agents and Chemotherapy (2014)

168 Citations

Novel salvage pathway utilizing farnesol and geranylgeraniol for protein isoprenylation.

Dean C. Crick;Douglas A. Andres;Charles J. Waechter.
Biochemical and Biophysical Research Communications (1997)

154 Citations

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