Christopher K. Cain

Best Publications

• Molecular Mechanisms of Fear Learning and Memory

  Joshua P. Johansen;Christopher K. Cain;Christopher K. Cain;Linnaea E. Ostroff;Joseph E. LeDoux;Joseph E. LeDoux

  1198
  Citations

• Brain mechanisms of fear extinction: historical perspectives on the contribution of prefrontal cortex

  Francisco Sotres-Bayon;Christopher K. Cain;Joseph E. LeDoux

  557
  Citations

• Long-term potentiation in the amygdala: a cellular mechanism of fear learning and memory.

  Torfi Sigurdsson;Valérie Doyère;Valérie Doyère;Christopher K. Cain;Joseph E. LeDoux

  447
  Citations

• Adrenergic transmission facilitates extinction of conditional fear in mice.

  Christopher K. Cain;Ashley M. Blouin;Mark Barad

  272
  Citations

• The role of amygdala nuclei in the expression of auditory signaled two-way active avoidance in rats

  June Seek Choi;Christopher K. Cain;Joseph E. Ledoux

  218
  Citations

• Evidence for recovery of fear following immediate extinction in rats and humans

  Daniela Schiller;Christopher K. Cain;Nina G. Curley;Jennifer S. Schwartz

  206
  Citations

• Fear and safety learning differentially affect synapse size and dendritic translation in the lateral amygdala

  Linnaea E. Ostroff;Christopher K. Cain;Joseph Bedont;Joseph Bedont;Marie Helene Monfils

  194
  Citations

• Temporally massed CS presentations generate more fear extinction than spaced presentations.

  Christopher K. Cain;Ashley M. Blouin;Mark Barad

  174
  Citations

• Sidman instrumental avoidance initially depends on lateral and basal amygdala and is constrained by central amygdala-mediated Pavlovian processes.

  Gabriel Lázaro-Muñoz;Joseph E. LeDoux;Christopher K. Cain

  166
  Citations

• L-Type Voltage-Gated Calcium Channels Are Required for Extinction, But Not for Acquisition or Expression, of Conditional Fear in Mice

  Chris K. Cain;Ashley M. Blouin;Mark Barad

  163
  Citations

• Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions.

  Mark D. Lindner;Melissa A. Plone;Chris K. Cain;Beata Frydel

  149
  Citations

• Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats.

  Mark D Lindner;Chris K Cain;Melissa A Plone;Beata R Frydel

  126
  Citations

• Therapeutic utility of non-peptidic CRF1 receptor antagonists in anxiety, depression, and stress-related disorders: evidence from animal models.

  John H. Kehne;Christopher K. Cain;Christopher K. Cain

  117
  Citations

• Synapses lacking astrocyte appear in the amygdala during consolidation of pavlovian threat conditioning

  Linnaea E. Ostroff;Mustfa K. Manzur;Christopher K. Cain;Joseph E. Ledoux

  95
  Citations

• Active vs. reactive threat responding is associated with differential c-Fos expression in specific regions of amygdala and prefrontal cortex.

  Raquel C.R. Martinez;Nikita Gupta;Gabriel Lázaro-Muñoz;Robert M. Sears

  94
  Citations

• Avoidance Problems Reconsidered.

  Christopher K Cain

  92
  Citations

• Escape from fear: a detailed behavioral analysis of two atypical responses reinforced by CS termination.

  Christopher K. Cain;Joseph E. LeDoux

  89
  Citations

• The L-type calcium channel blocker nifedipine impairs extinction, but not reduced contingency effects, in mice

  Christopher K. Cain;Bill P. Godsil;Shekib Jami;Mark Barad

  88
  Citations

• Heterogeneity in signaled active avoidance learning: substantive and methodological relevance of diversity in instrumental defensive responses to threat cues.

  Isaac R. Galatzer-Levy;Justin Moscarello;Esther M. Blessing;Jo Anna Klein

  87
  Citations

• d-Cycloserine augmentation of cognitive remediation in schizophrenia.

  Christopher K. Cain;Christopher K. Cain;Margaret McCue;Iruma Bello;Timothy Creedon

  85
  Citations