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Neuroscience

D-Index
47
Citations
6146
World Ranking
6545
National Ranking
2839

Overview

Alan R. Gintzler was affiliated with SUNY Downstate Medical Center in the United States. Their research spanned multiple fields including Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine. The subfields primarily addressed in their work were Cellular and Molecular Neuroscience, Physiology, Molecular Biology, Genetics, and Behavioral Neuroscience.

Their scientific contributions frequently explored topics such as Neuropeptides and Animal Physiology, Pain Mechanisms and Treatments, Estrogen and related hormone effects, Receptor Mechanisms and Signaling, Pharmacological Receptor Mechanisms and Effects, Stress Responses and Cortisol, and Sex and Gender in Healthcare.

Among the recent scholarly papers authored by Alan R. Gintzler were:

  • Arbiters of endogenous opioid analgesia: role of CNS estrogenic and glutamatergic systems, 2021, Translational research
  • Harnessing endogenous opioids for pain relief: Fantasy vs reality, 2020, Journal of Opioid Management

They also contributed to research published in collaboration with other authors, such as the paper "Relevance of Mu-Opioid Receptor Splice Variants and Plasticity of Their Signaling Sequelae to Opioid Analgesic Tolerance," published in 2020 in Cellular and Molecular Neurobiology, authored by Sumita Chakrabarti.

Frequent collaborators included Nai-Jiang Liu, Sumita Chakrabarti, Martin W. Wessendorf, and Emiliya M. Storman. Their work appeared regularly in venues such as Cellular and Molecular Neurobiology, Translational research, Journal of Opioid Management, and Microscopy and Microanalysis.

Best Publications

  • Endorphin-mediated increases in pain threshold during pregnancy.

    Unknown

  • Naltrexone-induced opiate receptor supersensitivity.

    R. Suzanne Zukin;R. Suzanne Zukin;Jonathan R. Sugarman;Melissa L. Fitz-Syage;Eliot L. Gardner

  • Estrogen and progesterone activate spinal kappa-opiate receptor analgesic mechanisms

    Mary E. Dawson-Basoa;Alan R. Gintzler

  • 17-β-Estradiol and progesterone modulate an intrinsic opioid analgesic system

    Mary Beth Dawson-Basoa;Alan R. Gintzler

  • Gestational and ovarian sex steroid antinociception: synergy between spinal κ and δ opioid systems

    Mary Dawson-Basoa;Alan R Gintzler

  • Prolonged ovarian sex steroid treatment of male rats produces antinociception: identification of sex-based divergent analgesic mechanisms

    Nai-Jiang Liu;Alan R. Gintzler

  • Formation of μ-/κ-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia

    Sumita Chakrabarti;Nai-Jiang Liu;Alan R. Gintzler

  • Chronic morphine augments adenylyl cyclase phosphorylation: relevance to altered signaling during tolerance/dependence.

    Sumita Chakrabarti;Lin Wang;Wei-Jen Tang;Alan R. Gintzler

  • Antibodies as a means of isolating and characterizing biologically active substances: presence of a non-peptide, morphine-like compound in the central nervous system

    Alan R. Gintzler;Aharon Levy;Sydney Spector

  • 17β-estradiol and progesterone positively modulate spinal cord dynorphin : relevance to the analgesia of pregnancy

    Victor M. Medina;Mary E. Dawson-Basoa;Alan R. Gintzler

  • Biochemical demonstration of mu-opioid receptor association with Gsα: enhancement following morphine exposure

    Sumita Chakrabarti;Annette Regec;Alan R. Gintzler

  • Spinal Synthesis of Estrogen and Concomitant Signaling by Membrane Estrogen Receptors Regulate Spinal κ- and μ-Opioid Receptor Heterodimerization and Female-Specific Spinal Morphine Antinociception

    Nai Jiang Liu;Sumita Chakrabarti;Stephen Schnell;Martin Wessendorf

  • Involvement of spinal cord δ opiate receptors in the antinociception of gestation and its hormonal simulation

    Mary Dawson-Basoa;Alan R Gintzler

  • Different G proteins mediate the opioid inhibition or enhancement of evoked [5-methionine]enkephalin release.

    Alan R. Gintzler;Hong Xu

  • Chronic Morphine Augments Gβγ/GsαStimulation of Adenylyl Cyclase: Relevance to Opioid Tolerance

    Sumita Chakrabarti;Mildred Rivera;Shui-Zhong Yan;Wei-Jen Tang

  • Chronic morphine induces the concomitant phosphorylation and altered association of multiple signaling proteins: A novel mechanism for modulating cell signaling

    Sumita Chakrabarti;Martin Oppermann;Alan R. Gintzler

  • Pain thresholds are elevated during pseudopregnancy.

    Alan R. Gintzler;Margaret C. Bohan

  • Effects of opioids on noncholinergic excitatory responses of the guinea-pig isolated ileum: inhibition of release of enteric substance P.

    Alan R. Gintzler;Jennie A. Scalisi

  • Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system.

    G.W. Pasternak;A.R. Gintzler;R.A. Houghten;G.S.F. Ling

  • Opioid tolerance and the emergence of new opioid receptor-coupled signaling.

    Alan R. Gintzler;Sumita Chakrabarti

  • Bimodal opioid regulation of cyclic AMP formation: implications for positive and negative coupling of opiate receptors to adenylyl cyclase.

    Lin Wang;Alan R. Gintzler

Frequent Co-Authors

Martin W. Wessendorf
Martin W. Wessendorf University of Minnesota
R. Suzanne Zukin
R. Suzanne Zukin Albert Einstein College of Medicine
Gavril W. Pasternak
Gavril W. Pasternak Memorial Sloan Kettering Cancer Center
James E. Zadina
James E. Zadina Tulane University

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Related Online Degrees & Career Pathways

Exploring neuroscience can open doors to a range of allied health and mental wellness careers. Many students combine neuroscience studies with counseling, therapy, or social work for diverse opportunities. For instance, some learners pursue online MFT programs to gain skills for supporting families and relationships, which complements neuroscience’s brain-based approach to behavior.

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Additionally, many students look for an accredited online psychology degree, which can provide foundational knowledge for roles in research, education, or mental health.

For those drawn to helping professions, earning a msw online degree can be a rewarding pathway. Social work offers career routes in mental health clinics, hospitals, and community organizations—a great fit for neuroscience graduates interested in making a direct clinical impact.

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