World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
60
Citations
11791
World Ranking
9771
National Ranking
2745

Overview

William C. Eckelman is affiliated with the National Institutes of Health in the United States. Their research spans multiple fields with a primary focus on Neuroscience and Medicine. The scientist has published extensively, with notable contributions in Biological Psychiatry, Behavioral Neuroscience, Cognitive Neuroscience, Psychiatry and Mental Health, and Epidemiology.

Their work covers several main topics, including:

  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Functional Brain Connectivity Studies
  • Treatment of Major Depression
  • Cytomegalovirus and herpesvirus research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Bipolar Disorder and Treatment

Frequent co-authors collaborating with William C. Eckelman include:

  • Martin P. Paulus (53 joint publications)
  • T. Kent Teague (38 joint publications)
  • Rayus Kuplicki (36 joint publications)
  • Robin L. Aupperle (26 joint publications)
  • Sahib S. Khalsa (26 joint publications)

The scientist has published numerous articles in key venues related to psychiatry and neuroscience. The most frequent publication venues are:

  • Brain Behavior and Immunity (16 publications)
  • Biological Psychiatry (10 publications)
  • Molecular Psychiatry (6 publications)
  • Translational Psychiatry (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)

Selected recent papers from their body of work include:

  • "Toll-Like Receptor Signaling in Depression" (2020), Psychoneuroendocrinology
  • "The kynurenine pathway in bipolar disorder: a meta-analysis on the peripheral blood levels of tryptophan and related metabolites" (2020), Molecular Psychiatry
  • "A Prospective Study of Acute Blood-Based Biomarkers for Sport-Related Concussion" (2020), Annals of Neurology
  • "Elevated peripheral inflammation is associated with attenuated striatal reward anticipation in major depressive disorder" (2021), Brain Behavior and Immunity
  • "Perceptual insensitivity to the modulation of interoceptive signals in depression, anxiety, and substance use disorders" (2021), Scientific Reports

In addition to journal articles, William C. Eckelman has contributed to book literature, publishing "Microorganisms and Mental Health" in 2023 under Springer Science+Business Media, which has received citations in related fields.

Best Publications

  • Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method

    Alan Breier;T. P. Su;R. Saunders;R. E. Carson

  • A series of halogenated heterodimeric inhibitors of prostate specific membrane antigen (PSMA) as radiolabeled probes for targeting prostate cancer.

    K. P. Maresca;S. M. Hillier;F. J. Femia;D. Keith

  • Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer.

    Shawn M. Hillier;Kevin P. Maresca;Frank J. Femia;John C. Marquis

  • 99mTc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen for Molecular Imaging of Prostate Cancer

    Shawn M. Hillier;Kevin P. Maresca;Genliang Lu;Ross D. Merkin

  • PET imaging of 5-HT1A receptor binding in patients with temporal lobe epilepsy

    M.T. Toczek;R.E. Carson;L. Lang;Y. Ma

  • The Progress and Promise of Molecular Imaging Probes in Oncologic Drug Development

    Gary J. Kelloff;Kenneth A. Krohn;Steven M. Larson;Ralph Weissleder

  • Quantification of Amphetamine-Induced Changes in [11C]Raclopride Binding with Continuous Infusion

    Richard E. Carson;Alan Breier;Andrea de Bartolomeis;Richard C. Saunders

  • Glut-1 and hexokinase expression: relationship with 2-fluoro-2-deoxy-D-glucose uptake in A431 and T47D cells in culture.

    Luigi Aloj;Corradina Caracó;Elaine Jagoda;William C. Eckelman

  • Kinetic Modeling of [11C]Raclopride: Combined PET-Microdialysis Studies

    Christopher J. Endres;Bhaskar S. Kolachana;Richard C. Saunders;Tom Su

  • Factors influencing DTPA conjugation with antibodies by cyclic DTPA anhydride.

    C. H. Paik;M. A. Ebbert;P. R. Murphy;C. R. Lassman

  • Development of fluorine-18-labeled 5-HT1A antagonists.

    Lixin Lang;E. Jagoda;B. Schmall;B.-K. Vuong

  • Radiolabeling with technetium-99m to study high-capacity and low-capacity biochemical systems.

    William C. Eckelman

  • Muscarinic cholinergic receptor measurements with [18F]FP-TZTP: control and competition studies.

    Richard E. Carson;Dale O. Kiesewetter;Elaine Jagoda;Margaret G. Der

  • The labeling of high affinity sites of antibodies with 99mTc.

    Chang H. Paik;Lan N.B. Phan;Jack J. Hong;Malekeh S. Sahami

  • Synthesis and SAR of 99mTc/Re-labeled small molecule prostate specific membrane antigen inhibitors with novel polar chelates

    Genliang Lu;Kevin P. Maresca;Shawn M. Hillier;Craig N. Zimmerman

  • One-step synthesis of 18F labeled [18F]-N-succinimidyl 4-(fluoromethyl)benzoate for protein labeling.

    Lixin Lang;William C. Eckelman

  • 123I-MIP-1072, a Small-Molecule Inhibitor of Prostate-Specific Membrane Antigen, Is Effective at Monitoring Tumor Response to Taxane Therapy

    Shawn M. Hillier;Ashley M. Kern;Kevin P. Maresca;John C. Marquis

  • Kinetic analysis of the 5-HT2A ligand [11C]MDL 100,907.

    Hiroshi Watabe;Michael A. Channing;Margaret G. Der;H. Richard Adams

  • Experiment assessment of mass effects in the rat: implications for small animal PET imaging.

    E.M. Jagoda;J.J. Vaquero;J. Seidel;M.V. Green

  • The Suitability of [11C]-α-Methyl-L-tryptophan as a Tracer for Serotonin Synthesis: Studies With Dual Administration of [11C] and [14C] Labeled Tracer:

    Susan E. Shoaf;Richard E. Carson;Daniel Hommer;Wendol A. Williams

Frequent Co-Authors

Richard E. Carson
Richard E. Carson Yale University
Dale O. Kiesewetter
Dale O. Kiesewetter National Institutes of Health
Peter Herscovitch
Peter Herscovitch National Institutes of Health
Kenner C. Rice
Kenner C. Rice National Institutes of Health
Jorge A. Carrasquillo
Jorge A. Carrasquillo Memorial Sloan Kettering Cancer Center
George P. Chrousos
George P. Chrousos National and Kapodistrian University of Athens
Richard C. Saunders
Richard C. Saunders National Institutes of Health
Stanley I. Rapoport
Stanley I. Rapoport National Institutes of Health
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Daniel W. Hommer
Daniel W. Hommer National Institutes of Health

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