Lawrence S. Kegeles

Best Publications

• Increased baseline occupancy of D2 receptors by dopamine in schizophrenia.

  Anissa Abi-Dargham;Janine Rodenhiser;David Printz;Yolanda Zea-Ponce

  1365
  Citations

• Increased dopamine transmission in schizophrenia: relationship to illness phases.

  Marc Laruelle;Anissa Abi-Dargham;Anissa Abi-Dargham;Roberto Gil;Roberto Gil;Lawrence Kegeles

  903
  Citations

• Imaging human mesolimbic dopamine transmission with positron emission tomography. Part II: amphetamine-induced dopamine release in the functional subdivisions of the striatum.

  Diana Martinez;Mark Slifstein;Allegra Broft;Osama Mawlawi

  644
  Citations

• Increased synaptic dopamine function in associative regions of the striatum in schizophrenia.

  Lawrence S. Kegeles;Anissa Abi-Dargham;W. Gordon Frankle;Roberto Gil

  636
  Citations

• Glutamate, Dopamine, and Schizophrenia

  Marc Laruelle;Lawrence S. Kegeles;Anissa Abi-Dargham

  618
  Citations

• Alcohol Dependence Is Associated with Blunted Dopamine Transmission in the Ventral Striatum

  Diana Martinez;Roberto Gil;Mark Slifstein;Dah Ren Hwang

  534
  Citations

• Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia.

  Lawrence S Kegeles;Anissa Abi-Dargham;Yolanda Zea-Ponce;Janine Rodenhiser-Hill

  481
  Citations

• Decreased Regional Brain Metabolism After ECT

  Mitchell S. Nobler;Maria A. Oquendo;Lawrence S. Kegeles;Kevin M. Malone

  456
  Citations

• Positron emission tomography of regional brain metabolic responses to a serotonergic challenge and lethality of suicide attempts in major depression.

  Maria A. Oquendo;Giovanni P. A. Placidi;Kevin M. Malone;Carl Campbell

  405
  Citations

• Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention

  J A Lieberman;J A Lieberman;R R Girgis;R R Girgis;G Brucato;G Brucato;H Moore;H Moore

  404
  Citations

• Randomized Controlled Crossover Trial of Ketamine in Obsessive-Compulsive Disorder: Proof-of-Concept

  Carolyn I Rodriguez;Lawrence S Kegeles;Lawrence S Kegeles;Amanda Levinson;Tianshu Feng;Tianshu Feng

  361
  Citations

• Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy.

  Lawrence S. Kegeles;Xiangling Mao;Arielle D. Stanford;Ragy Girgis

  348
  Citations

• Pathway-Specific Dopamine Abnormalities in Schizophrenia.

  Jodi J. Weinstein;Muhammad O. Chohan;Mark Slifstein;Lawrence S. Kegeles

  324
  Citations

• Sex Differences in Striatal Dopamine Release in Young Adults After Oral Alcohol Challenge: A Positron Emission Tomography Imaging Study With [11C]Raclopride

  Nina B.L. Urban;Lawrence S. Kegeles;Mark Slifstein;Xiaoyan Xu

  267
  Citations

• Baseline and Amphetamine-Stimulated Dopamine Activity Are Related in Drug-Naïve Schizophrenic Subjects

  Anissa Abi-Dargham;Elsmarieke van de Giessen;Elsmarieke van de Giessen;Mark Slifstein;Lawrence S. Kegeles

  250
  Citations

• Imaging glutamate in schizophrenia: review of findings and implications for drug discovery.

  E M P Poels;L S Kegeles;J T Kantrowitz;M Slifstein

  249
  Citations

• Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain.

  Clifford M. Cassidy;Clifford M. Cassidy;Fabio A. Zucca;Ragy R. Girgis;Seth C. Baker

  239
  Citations

• In vivo vulnerability to competition by endogenous dopamine: comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C]-raclopride.

  Rajesh Narendran;Dah Ren Hwang;Mark Slifstein;Peter S. Talbot

  226
  Citations

• GABA level, gamma oscillation, and working memory performance in schizophrenia

  Chi-Ming A. Chen;Arielle D. Stanford;Xiangling Mao;Anissa Abi-Dargham

  214
  Citations

• Comparative evaluation in nonhuman primates of five PET radiotracers for imaging the serotonin transporters: [11C]McN 5652, [11C]ADAM, [11C]DASB, [11C]DAPA, and [11C]AFM.

  Yiyun Huang;Dah Ren Hwang;Raj Narendran;Yasuhiko Sudo

  211
  Citations