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Biology and Biochemistry

D-Index
63
Citations
15723
World Ranking
10130
National Ranking
104

Overview

Søren Bak is affiliated with the University of Copenhagen in Denmark, focusing on research in Agricultural and Biological Sciences as well as Biochemistry, Genetics and Molecular Biology. Their work covers a broad range of topics primarily related to molecular biology, plant science, insect science, and ecological interactions.

Their research emphasizes areas such as natural product bioactivities and synthesis, plant biochemistry and biosynthesis, and the study of interactions between plants and animals. Specific topics include plant parasitism and resistance, insect-plant interactions and control, and biological control of invasive species. Additionally, their work encompasses advances in Cucurbitaceae research.

Key recent papers authored or co-authored by Søren Bak include:

  • A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination, 2022, Nature Communications
  • Plant triterpenoids with bond-missing skeletons: biogenesis, distribution and bioactivity, 2020, Natural Product Reports
  • Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol, 2020, Microbial Cell Factories
  • Biosynthesis and biotechnological production of the anti-obesity agent celastrol, 2023, Nature Chemistry
  • Variation of chemical compounds in wild Heliconiini reveals ecological factors involved in the evolution of chemical defenses in mimetic butterflies, 2020, Ecology and Evolution

Frequent collaborators of Søren Bak include Érika C. Pinheiro de Castro, Aldo Almeida, Pablo D. Cárdenas, Karel Miettinen, and Dan Stærk. These co-authors have contributed to multiple projects and publications, reflecting interdisciplinary research engagement.

The scientist has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Nature Chemistry, Natural Product Reports, and Microbial Cell Factories, indicating a diverse publication profile across preprint servers and peer-reviewed journals.

Their subfields of study span molecular biology, plant science, insect science, ecology, evolution, behavior and systematics, and genetics. These breadths demonstrate interdisciplinary links between chemistry, biology, and ecological sciences supporting their research on biosynthesis, biochemical pathways, and ecological defenses.

Best Publications

  • Plant Defense against Insect Herbivores

    Joel Fürstenberg-Hägg;Mika Zagrobelny;Søren Bak

  • Molecular activities, biosynthesis and evolution of triterpenoid saponins.

    Jörg M. Augustin;Vera Kuzina;Sven B. Andersen;Søren Bak

  • β-Glucosidases as detonators of plant chemical defense

    Anne Vinther Morant;Kirsten Jørgensen;Charlotte Jørgensen;Suzanne Michelle Paquette

  • Metabolon formation and metabolic channeling in the biosynthesis of plant natural products.

    Kirsten Jørgensen;Anne Vinther Rasmussen;Marc Morant;Allan Holm Nielsen

  • Comparative Genomics of Rice and Arabidopsis. Analysis of 727 Cytochrome P450 Genes and Pseudogenes from a Monocot and a Dicot

    David R. Nelson;Mary A. Schuler;Suzanne M. Paquette;Daniele Werck-Reichhart

  • CYP83B1, a Cytochrome P450 at the Metabolic Branch Point in Auxin and Indole Glucosinolate Biosynthesis in Arabidopsis

    Søren Bak;Frans E. Tax;Kenneth A. Feldmann;David W. Galbraith

  • Cyanogenic glucosides and plant–insect interactions

    Mika Zagrobelny;Søren Bak;Anne Vinther Rasmussen;Bodil Jørgensen

  • CYP703 Is an Ancient Cytochrome P450 in Land Plants Catalyzing in-Chain Hydroxylation of Lauric Acid to Provide Building Blocks for Sporopollenin Synthesis in Pollen

    Marc Morant;Kirsten Jørgensen;Hubert Schaller;Franck Pinot

  • Plant cytochromes P450: tools for pharmacology, plant protection and phytoremediation

    Marc Morant;Søren Bak;Birger Lindberg Møller;Danièle Werck-Reichhart

  • Plant P450s as versatile drivers for evolution of species-specific chemical diversity.

    Björn Hamberger;Søren Bak

  • On the origin of family 1 plant glycosyltransferases.

    Suzanne Paquette;Birger Lindberg Møller;Søren Bak

  • Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers. Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology.

    Kirsten Jørgensen;Søren Bak;Peter Kamp Busk;Charlotte Sørensen

  • The involvement of two p450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis.

    Søren Bak;René Feyereisen;René Feyereisen

  • Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis

    David B. Tattersall;Søren Bak;Patrik R. Jones;Carl Erik Olsen

  • Substrate specificity of plant UDP-dependent glycosyltransferases predicted from crystal structures and homology modeling.

    Sarah A. Osmani;Søren Bak;Birger Lindberg Møller

  • CYP83A1 and CYP83B1, Two Nonredundant Cytochrome P450 Enzymes Metabolizing Oximes in the Biosynthesis of Glucosinolates in Arabidopsis

    Peter Naur;Bent Larsen Petersen;Michael Dalgaard Mikkelsen;Søren Bak

  • Cyanogenesis in plants and arthropods.

    Mika Zagrobelny;Søren Bak;Birger Lindberg Møller

  • Intron–Exon Organization and Phylogeny in a Large Superfamily, the Paralogous Cytochrome P450 Genes of Arabidopsis thaliana

    Suzanne M. Paquette;Søren Bak;René Feyereisen

  • Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogenic glucoside dhurrin

    Søren Bak;Rachel Alice Kahn;Hanne Linde Nielsen;Birger Lindberg Møller

  • Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome

    Charlotte Kristensen;Marc Morant;Carl Erik Olsen;Claus T. Ekstrøm

Frequent Co-Authors

Birger Lindberg Møller
Birger Lindberg Møller University of Copenhagen
Carl Erik Olsen
Carl Erik Olsen University of Copenhagen
Barbara Ann Halkier
Barbara Ann Halkier University of Copenhagen
René Feyereisen
René Feyereisen University of Copenhagen
Danièle Werck-Reichhart
Danièle Werck-Reichhart Centre national de la recherche scientifique, CNRS
Søren Balling Engelsen
Søren Balling Engelsen University of Copenhagen
Alain Goossens
Alain Goossens Ghent University
Anne Imberty
Anne Imberty Grenoble Alpes University
Hubert Schaller
Hubert Schaller Institut de Biologie Moléculaire des Plantes
Heiko Vogel
Heiko Vogel Max Planck Society

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