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Genetics

D-Index
49
Citations
24542
World Ranking
3962
National Ranking
1709

Overview

Sarah E. Calvo is affiliated with the Broad Institute in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with a significant emphasis on mitochondrial biology and genetic disorders. Their scholarly output spans 45 publications within these fields.

Their work frequently appears in several publication venues, including:

  • Nature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Canadian Journal of Linguistics / La revue canadienne de linguistique
  • Nucleic Acids Research
  • Cell

The scientist's research covers a range of topics, such as:

  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders
  • Genomics and Rare Diseases
  • RNA modifications and cancer
  • Genomic variations and chromosomal abnormalities
  • Metabolomics and Mass Spectrometry Studies
  • RNA and protein synthesis mechanisms

Their subfields of study include:

  • Molecular Biology
  • Genetics
  • Clinical Biochemistry
  • Cancer Research
  • Pulmonary and Respiratory Medicine

Several recent papers illustrate their contributions to the scientific community:

  • "MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations", 2020, Nucleic Acids Research
  • "A genomic mutational constraint map using variation in 76,156 human genomes", 2023, Nature
  • "Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism", 2020, Cell
  • "Nuclear genetic control of mtDNA copy number and heteroplasmy in humans", 2023, Nature
  • "Mitochondrial DNA variation across 56,434 individuals in gnomAD", 2022, Genome Research

Collaborations feature several frequent co-authors, including:

  • Vamsi K. Mootha
  • Rahul Gupta
  • Hardik Shah
  • Masahiro Kanai
  • Nicholas A. Watts

Best Publications

  • A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

    David J. Pagliarini;Sarah E. Calvo;Betty Chang;Sunil A. Sheth

  • The genome sequence of the filamentous fungus Neurospora crassa

    James E. Galagan;Sarah E. Calvo;Katherine A. Borkovich;Eric U. Selker

  • The genome sequence of the rice blast fungus Magnaporthe grisea

    Ralph A. Dean;Nicholas J. Talbot;Daniel J. Ebbole;Mark L. Farman

  • Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

    James E. Galagan;Sarah E. Calvo;Christina Cuomo;Li Jun Ma

  • Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis

    Jörg Kämper;Regine Kahmann;Michael Bölker;Li-Jun Ma

  • MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins.

    Sarah E. Calvo;Sarah E. Calvo;Karl R. Clauser;Vamsi K. Mootha;Vamsi K. Mootha

  • MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations.

    Sneha Rath;Sneha Rath;Rohit Sharma;Rohit Sharma;Rahul Gupta;Rahul Gupta;Tslil Ast;Tslil Ast

  • The Fusarium graminearum Genome Reveals a Link Between Localized Polymorphism and Pathogen Specialization

    Christina A. Cuomo;Ulrich Güldener;Jin Rong Xu;Frances Trail

  • Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

    Sarah E. Calvo;David J. Pagliarini;David J. Pagliarini;Vamsi K. Mootha;Vamsi K. Mootha

  • The Genome of M. Acetivorans Reveals Extensive Metabolic and Physiological Diversity

    James E. Galagan;Chad Nusbaum;Alice Roy;Matthew G. Endrizzi;Matthew G. Endrizzi;Matthew G. Endrizzi

  • EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex

    Yasemin Sancak;Andrew L. Markhard;Toshimori Kitami;Toshimori Kitami;Erika Kovács-Bogdán

  • The mitochondrial proteome and human disease.

    Sarah E. Calvo;Vamsi K. Mootha

  • Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing

    Sarah E. Calvo;Alison G. Compton;Steven G. Hershman;Steven G. Hershman;Sze Chern Lim;Sze Chern Lim

  • MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion

    Antonella Spinazzola;Carlo Viscomi;Erika Fernandez-Vizarra;Franco Carrara

  • Systematic identification of human mitochondrial disease genes through integrative genomics.

    Sarah Calvo;Mohit Jain;Mohit Jain;Xiaohui Xie;Sunil A Sheth;Sunil A Sheth

  • Genomic Analysis of the Basal Lineage Fungus Rhizopus oryzae Reveals a Whole-Genome Duplication

    Li Jun Ma;Ashraf S. Ibrahim;Christopher Skory;Manfred G. Grabherr

  • High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency

    Sarah E Calvo;Elena J Tucker;Elena J Tucker;Alison G Compton;Denise M Kirby

  • A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation

    Jason D. Arroyo;Jason D. Arroyo;Alexis A. Jourdain;Alexis A. Jourdain;Sarah E. Calvo;Sarah E. Calvo;Carmine A. Ballarano;Carmine A. Ballarano

  • The Complete Genome and Proteome of Mycoplasma mobile

    Jacob D. Jaffe;Nicole Stange-Thomann;Cherylyn Smith;David DeCaprio

  • Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

    Cornelia Kornblum;Thomas J Nicholls;Tobias B Haack;Susanne Schöler

Frequent Co-Authors

Vamsi K. Mootha
Vamsi K. Mootha Harvard Medical School
David R. Thorburn
David R. Thorburn Murdoch Children's Research Institute
Salvatore DiMauro
Salvatore DiMauro Columbia University
John Christodoulou
John Christodoulou University of Melbourne
Michael T. Ryan
Michael T. Ryan University of Sydney
Holger Prokisch
Holger Prokisch Technical University of Munich
James E. Galagan
James E. Galagan Boston University
Steven A. Carr
Steven A. Carr Broad Institute
Yasushi Okazaki
Yasushi Okazaki Juntendo University
Thomas Meitinger
Thomas Meitinger Technical University of Munich

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