Roger Le Grand

Best Publications

• Animal models for COVID-19.

  César Muñoz-Fontela;William E. Dowling;Simon G.P. Funnell;Pierre S. Gsell

  822
  Citations

• Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages

  Karine Labadie;Thibaut Larcher;Christophe Joubert;Abdelkrim Mannioui

  670
  Citations

• Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates

  Virginie Sandrin;Bertrand Boson;Bertrand Boson;Patrick Salmon;Patrick Salmon

  458
  Citations

• Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates.

  Pauline Maisonnasse;Jérémie Guedj;Vanessa Contreras;Sylvie Behillil;Sylvie Behillil

  366
  Citations

• Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia.

  Laurence Dupuis-Maguiraga;Marion Noret;Sonia Brun;Roger Le Grand

  340
  Citations

• Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS

  Christopher Kornfeld;Mickaël J.-Y. Ploquin;Ivona Pandrea;Abdourahmane Faye

  330
  Citations

• On chikungunya acute infection and chloroquine treatment

  Xavier De Lamballerie;Véronique Boisson;Jean-Charles Reynier;Sébastien Enault

  296
  Citations

• Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein

  Yiu‐Wing Kam;Fok‐Moon Lum;Fok‐Moon Lum;Teck‐Hui Teo;Wendy W. L. Lee

  235
  Citations

• Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection

  Abderaouf Damouche;Thierry Lazure;Véronique Avettand-Fènoël;Nicolas Huot

  229
  Citations

• Expression of chemokines and their receptors in human and simian astrocytes: Evidence for a central role of TNFα and IFNγ in CXCR4 and ccr5 modulation

  Juliana Croitoru-Lamoury;Juliana Croitoru-Lamoury;Gilles J. Guillemin;François D. Boussin;Barbara Mognetti

  226
  Citations

• Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.

  David Hallengärd;Maria Kakoulidou;Aleksei Lulla;Beate M. Kümmerer

  212
  Citations

• Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

  Laurent Dembélé;Jean-François Franetich;Audrey Lorthiois;Audrey Gego

  208
  Citations

• Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection.

  Philip J.M. Brouwer;Mitch Brinkkemper;Pauline Maisonnasse;Nathalie Dereuddre-Bosquet

  191
  Citations

• Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression.

  Benoît Malleret;Benoît Malleret;Benjamin Manéglier;Ingrid Karlsson;Ingrid Karlsson;Pierre Lebon

  191
  Citations

• Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4+ T cells

  Dapeng Li;Gabrielle Romain;Anne Laure Flamar;Dorothée Duluc

  190
  Citations

• Surfactant-free anionic PLA nanoparticles coated with HIV-1 p24 protein induced enhanced cellular and humoral immune responses in various animal models.

  Yasemin Ataman-Önal;Séverine Munier;Arnaud Ganée;Céline Terrat

  187
  Citations

• Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques

  C Moog;N Dereuddre-Bosquet;J-L Teillaud;M E Biedma

  176
  Citations

• Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection.

  Pierre Roques;Simon-Djamel Thiberville;Laurence Dupuis-Maguiraga;Fok-Moon Lum

  167
  Citations

• Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery

  Laurent Dembele;Audrey Gego;Audrey Gego;Anne-Marie Zeeman;Jean-François Franetich;Jean-François Franetich

  162
  Citations

• The Integrase Inhibitors Dolutegravir and Raltegravir Exert Proadipogenic and Profibrotic Effects and Induce Insulin Resistance in Human/Simian Adipose Tissue and Human Adipocytes

  Jennifer Gorwood;Christine Bourgeois;Valérie Pourcher;Valérie Pourcher;Guillaume Pourcher

  130
  Citations