Paul G.M. Luiten

What is he best known for?

The fields of study he is best known for:

• Internal medicine
• Neuron
• Neuroscience

His scientific interests lie mostly in Neuroscience, Neuroprotection, Internal medicine, Endocrinology and Anatomy. His study in Dentate gyrus, Hippocampal formation, Hippocampus, Cholinergic and Central nervous system are all subfields of Neuroscience. His work deals with themes such as Stroke, Signal transduction, Neurodegeneration and Immunology, which intersect with Neuroprotection.

His Internal medicine research includes themes of Sleep restriction, Sleep in non-human animals and Nucleus. His Endocrinology research is multidisciplinary, incorporating perspectives in Sleep deprivation, Insomnia and Sleep disorder. He has included themes like Diagonal band of Broca and Proprioception in his Anatomy study.

His most cited work include:

• Cerebral microvascular pathology in aging and Alzheimer's disease. (859 citations)
• Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases. (489 citations)
• Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing? (363 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Neuroscience, Internal medicine, Endocrinology, Neuroprotection and Hippocampus. His research integrates issues of Long-term potentiation, Muscarinic acetylcholine receptor and Anatomy in his study of Neuroscience. His Internal medicine research incorporates themes from Sleep deprivation, Lesion and Sleep disorder.

He focuses mostly in the field of Endocrinology, narrowing it down to topics relating to Receptor and, in certain cases, Senescence. His Neuroprotection research is multidisciplinary, incorporating elements of Excitotoxicity, Signal transduction, Neurodegeneration and Tumor necrosis factor alpha. His study on Tumor necrosis factor alpha also encompasses disciplines like

• Proinflammatory cytokine, which have a strong connection to Neuroinflammation,
• Disease that intertwine with fields like Depression and Cerebral blood flow.

He most often published in these fields:

• Neuroscience (50.31%)
• Internal medicine (31.29%)
• Endocrinology (30.67%)

What were the highlights of his more recent work (between 2011-2020)?

• Neuroscience (50.31%)
• Immunology (9.20%)
• Neuroinflammation (8.59%)

In recent papers he was focusing on the following fields of study:

Paul G.M. Luiten mainly investigates Neuroscience, Immunology, Neuroinflammation, Pharmacology and Central nervous system. His Neuroscience research incorporates elements of Stretch-activated ion channel and T-type calcium channel. His Neuroinflammation research is multidisciplinary, relying on both Proinflammatory cytokine and Tumor necrosis factor alpha.

His Proinflammatory cytokine study combines topics in areas such as Cancer research, Cytokine, Microglia, Neuroprotection and Signal transduction. His Tumor necrosis factor alpha research is within the category of Endocrinology. His study looks at the relationship between Central nervous system and topics such as Agonist, which overlap with Positron emission tomography.

Between 2011 and 2020, his most popular works were:

• Lipocalin 2: Novel component of proinflammatory signaling in Alzheimer's disease (105 citations)
• Lipocalin 2: Novel component of proinflammatory signaling in Alzheimer's disease (105 citations)
• The Role of Indoleamine 2,3-Dioxygenase in a Mouse Model of Neuroinflammation-Induced Depression (82 citations)

In his most recent research, the most cited papers focused on:

• Internal medicine
• Neuron
• Biochemistry

His primary areas of investigation include Neuroinflammation, Immunology, Inflammation, Proinflammatory cytokine and Tumor necrosis factor alpha. His Neuroinflammation research incorporates themes from Signal transduction and Depression. Paul G.M. Luiten has included themes like Cancer research, Cytokine, Neurodegeneration, Microglia and Neuroprotection in his Signal transduction study.

His Depression research incorporates elements of Blood–brain barrier, Bioinformatics and Internal medicine, Disease, Myocardial infarction. His research on Myocardial infarction often connects related areas such as Endocrinology. Paul G.M. Luiten integrates many fields, such as Indoleamine 2,3-dioxygenase, Pharmacology, Immune system, Behavioural despair test and Lipopolysaccharide, in his works.