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Biology and Biochemistry

D-Index
48
Citations
7848
World Ranking
18439
National Ranking
7528

Overview

Lynell Warren Klassen is affiliated with the University of Nebraska Medical Center in the United States. Their research primarily focuses on medical sciences, with several contributions to subfields such as rheumatology, immunology and allergy, cancer research, immunology, and molecular biology.

Their published work spans a variety of topics including rheumatoid arthritis research and therapies, systemic lupus erythematosus research, cell adhesion molecules research, cancer, lipids, and metabolism, immunotherapy and immune responses, RNA interference and gene delivery, and liver disease diagnosis and treatment.

Frequent coauthors in Klassen's research include Geoffrey M. Thiele, Michael J. Duryee, Carlos D. Hunter, Monte S. Willis, and Dean J. Tuma.

Key recent papers authored or coauthored by Klassen include:

  • Immunogenic and inflammatory responses to citrullinated proteins are enhanced following modification with malondialdehyde-acetaldehyde adducts, 2020, International Immunopharmacology
  • Correction: Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival, 2023, Clinical & Experimental Metastasis
  • INACTIVATION OF MANGANESE SUPEROXIDE DISMUTASE BY IRREVERSIBLE COVALENT OXIDATIVE MODIFICATION IN CARDIOVASCULAR DISEASE, 2020, Journal of the American College of Cardiology
  • Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde, 2020, UNC Libraries
  • Autoimmune Hepatitis Induced by Syngeneic Liver Cytosolic Proteins Biotransformed by Alcohol Metabolites, 2020, UNC Libraries

Klassen's work has appeared in several publication venues, most frequently in:

  • UNC Libraries
  • International Immunopharmacology
  • Clinical & Experimental Metastasis
  • Journal of the American College of Cardiology

Best Publications

  • Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications

    J R O'Dell;C E Haire;C E Haire;N Erikson;W Drymalski

  • Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications: Results of a two-year, randomized, double-blind, placebo-controlled trial

    James R. O'Dell;Robert Leff;Gail Paulsen;Claire Haire

  • Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration

    Dean J. Tuma;Geoffrey Milton Thiele;Dongsheng Xu;Lynell Warren Klassen

  • Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes.

    H T Petrie;L W Klassen;H D Kay

  • TREATMENT OF EARLY RHEUMATOID ARTHRITIS WITH MINOCYCLINE OR PLACEBO Results of a Randomized, Double-Blind, Placebo-Controlled Trial

    James R. O'Dell;Claire E. Haire;William Palmer;Walter Drymalski

  • Detection of circulating antibodies against malondialdehyde‐acetaldehyde adducts in patients with alcohol‐induced liver disease

    Roberta Rolla;Daria Vay;Elisa Mottaran;Monica Parodi

  • Treatment of early seropositive rheumatoid arthritis: A two-year, double-blind comparison of minocycline and hydroxychloroquine

    James R. O'Dell;Kent W. Blakely;Jack A. Mallek;P. James Eckhoff

  • Malondialdehyde-acetaldehyde adducts and anti-malondialdehyde-acetaldehyde antibodies in rheumatoid arthritis.

    Geoffrey Milton Thiele;Michael J. Duryee;Daniel R Anderson;Lynell Warren Klassen

  • Influenza immunization in systemic lupus erythematosus. A double-blind trial.

    G W Williams;A D Steinberg;J L Reinertsen;L W Klassen

  • Treatment of early seropositive rheumatoid arthritis with minocycline: four-year followup of a double-blind, placebo-controlled trial.

    James Robert O'Dell;Gail Paulsen;Claire E. Haire;Kent Blakely

  • Soluble proteins modified with acetaldehyde and malondialdehyde are immunogenic in the absence of adjuvant.

    Geoffrey Milton Thiele;Dean J. Tuma;Dean J. Tuma;Monte S. Willis;Jacqueline A. Miller;Jacqueline A. Miller

  • HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments

    James Robert O'Dell;Barbara S. Nepom;Claire Haire;Vivian H. Gersuk

  • Selective Loss of Suppressor Cell Function in New Zealand Mice Induced by NTA

    Lynell W. Klassen;R. S. Krakauer;Alfred D. Steinberg

  • Malondialdehyde-acetaldehyde adduct is the dominant epitope after MDA modification of proteins in atherosclerosis

    Michael J. Duryee;Lynell Warren Klassen;Courtney S. Schaffert;Courtney S. Schaffert;Dean J. Tuma

  • Association of malondialdehyde-acetaldehyde (MAA) adducted proteins with atherosclerotic-induced vascular inflammatory injury

    Gary E Hill;Jacqueline A Miller;B.Timothy Baxter;Lynell W Klassen

  • Nosocomial Legionnaires' disease: Occurrence in recipients of bone marrow transplants

    John W. Kugler;Jamés O. Armitage;Charles M. Helms;Lynell W. Klassen

  • Immunologic mechanisms of alcoholic liver injury.

    Geoffrey Milton Thiele;Thomas L. Freeman;Thomas L. Freeman;Lynell Warren Klassen

  • IL-6 and its receptors in coronary artery disease and acute myocardial infarction

    Daniel R Anderson;Joseph T. Poterucha;Ted R Mikuls;Ted R Mikuls;Michael J. Duryee;Michael J. Duryee

  • Detection of circulating antibodies to malondialdehyde-acetaldehyde adducts in ethanol-fed rats

    Dongsheng Xu;Geoffrey M. Thiele;John L. Beckenhauer;Lynell W. Klassen

  • Immune mechanisms of alcohol‐induced liver disease

    Lynell W. Klassen;Lynell W. Klassen;Dean Tuma;Dean Tuma;Michael F. Sorrell;Michael F. Sorrell

Frequent Co-Authors

Geoffrey M. Thiele
Geoffrey M. Thiele University of Nebraska Medical Center
Dean J. Tuma
Dean J. Tuma University of Nebraska Medical Center
James O. Armitage
James O. Armitage University of Nebraska Medical Center
Howard T. Petrie
Howard T. Petrie Scripps Research Institute
Debra J. Romberger
Debra J. Romberger University of Nebraska Medical Center
James E. Talmadge
James E. Talmadge University of Nebraska Medical Center
Concetta C. DiRusso
Concetta C. DiRusso University of Nebraska–Lincoln
Paul N. Black
Paul N. Black University of Nebraska–Lincoln
Dong Wang
Dong Wang Peking University
Emanuele Albano
Emanuele Albano University of Eastern Piedmont Amadeo Avogadro

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