Lydia Lynch

Best Publications

• Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

  Xavier Michelet;Xavier Michelet;Lydia Dyck;Andrew Hogan;Roisin M Loftus

  606
  Citations

• Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

  Lydia Lynch;Lydia Lynch;Michael Nowak;Bindu Varghese;Justice Clark

  569
  Citations

• Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue

  Lydia Lynch;Xavier Michelet;Sai Zhang;Patrick J Brennan

  402
  Citations

• Srebp-controlled glucose metabolism is essential for NK cell functional responses

  Nadine Assmann;Katie L O'Brien;Raymond P Donnelly;Lydia Dyck

  352
  Citations

• Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships.

  Aoife O’Donovan;Brian M. Hughes;George M. Slavich;Lydia Lynch

  344
  Citations

• γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.

  Ayano C. Kohlgruber;Ayano C. Kohlgruber;Shani T. Gal-Oz;Nelson M. LaMarche;Nelson M. LaMarche;Moto Shimazaki

  326
  Citations

• Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis

  Cathal Harmon;Mark W Robinson;Fiona Hand;Dalal Almuaili

  324
  Citations

• Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity

  Lydia Lynch;Donal O'Shea;Desmond C. Winter;Justin Geoghegan

  302
  Citations

• Are Natural Killer Cells Protecting the Metabolically Healthy Obese Patient

  Lydia A. Lynch;Jean M. O'Connell;Anna K. Kwasnik;Thomas J. Cawood

  293
  Citations

• Interplay between the immune system and adipose tissue in obesity.

  Mark Exley;Laura Elizabeth Hand;Donal O'Shea;Lydia Lynch

  286
  Citations

• Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus

  Unknown

  252
  Citations

• Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis

  A. E. Hogan;A. M. Tobin;T. Ahern;M. A. Corrigan

  212
  Citations

• Altered Distribution and Increased IL-17 Production by Mucosal-Associated Invariant T Cells in Adult and Childhood Obesity

  Eirin Carolan;Laura M. Tobin;Bozgana A. Mangan;Michelle Corrigan

  197
  Citations

• iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy.

  Lydia Lynch;Andrew E. Hogan;Danielle Duquette;Chantel Lester

  191
  Citations

• Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity.

  Selma Boulenouar;Selma Boulenouar;Xavier Michelet;Xavier Michelet;Danielle Duquette;David Alvarez

  189
  Citations

• Adipose Tissue Inflammation in the Pathogenesis of Type 2 Diabetes

  Unknown

  186
  Citations

• Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex.

  Harald Prüss;Harald Prüss;Harald Prüss;Andrea Tedeschi;Andrea Tedeschi;Andrea Tedeschi;Aude Thiriot;Lydia Lynch

  185
  Citations

• Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

  Noella Lopes;Claire McIntyre;Stefania Martin;Mathilde Raverdeau

  183
  Citations

• Natural killer cells in obesity: impaired function and increased susceptibility to the effects of cigarette smoke.

  Donal O'Shea;Tom J. Cawood;Cliona O'Farrelly;Lydia Lynch

  177
  Citations

• UCP1 governs liver extracellular succinate and inflammatory pathogenesis

  Evanna L. Mills;Cathal Harmon;Cathal Harmon;Mark P. Jedrychowski;Haopeng Xiao

  163
  Citations