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Chemistry

D-Index
71
Citations
15707
World Ranking
5653
National Ranking
1744

Research.com Recognitions

  • 2019 - Chirality Medal, Società Chimica Italiana
  • 1978 - Fellow of Alfred P. Sloan Foundation

Overview

Laurence A. Nafie is affiliated with Syracuse University in the United States and has contributed significantly to the fields of Biochemistry, Genetics and Molecular Biology, and Chemistry. Their research primarily focuses on areas such as Molecular Biology, Spectroscopy, Organic Chemistry, Biophysics, and Infectious Diseases.

The scientist's work encompasses several main topics, including:

  • Molecular spectroscopy and chirality
  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics
  • Axial and Atropisomeric Chirality Synthesis
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Spectroscopy and Quantum Chemical Studies
  • Analytical Chemistry and Chromatography

Laurence A. Nafie's recent notable papers include:

  • "Vibrational optical activity: From discovery and development to future challenges," 2020, Chirality
  • "Isolation, Total Synthesis, and Absolute Configuration Determination of Renoprotective Dimeric N-Acetyldopamine-Adenine Hybrids from the Insect Aspongopus chinensis," 2020, Organic Letters
  • "Computational methods and points for attention in absolute configuration determination," 2023, Frontiers in Natural Products
  • "Recent advances in linear and nonlinear Raman spectroscopy. Part XIV," 2020, Journal of Raman Spectroscopy
  • "Conformational Variability Correlation Prediction of Transmissibility and Neutralization Escape Ability for Multiple Mutation SARS-CoV-2 Strains using SSSCPreds," 2021, ACS Omega

Frequent collaborators in their research include:

  • Rina K. Dukor
  • Philippe Colomban
  • Howell G. M. Edwards
  • Hiroshi Izumi
  • Hiro-o Hamaguchi

Laurence A. Nafie publishes often in journals such as:

  • Journal of Raman Spectroscopy
  • ACS Omega
  • Chemical Communications
  • Chirality
  • Organic Letters

The scientist has received recognition through awards including the Chirality Medal from Società Chimica Italiana in 2019 and was named a Fellow of the Alfred P. Sloan Foundation in 1978.

Best Publications

  • Absolute configuration determination of chiral molecules in the solution state using vibrational circular dichroism.

    Teresa B. Freedman;Xiaolin Cao;Rina K. Dukor;Laurence A. Nafie

  • Vibrational Optical Activity: Principles and Applications

    Laurence A. Nafie

  • Vibrational circular dichroism

    L. A. Nafie;T. A. Keiderling;P. J. Stephens

  • INFRARED AND RAMAN VIBRATIONAL OPTICAL ACTIVITY: Theoretical and Experimental Aspects

    Laurence A. Nafie

  • Determination of absolute configuration of chiral molecules using vibrational optical activity: a review.

    Yanan He;Bo Wang;Rina K. Dukor;Laurence A. Nafie

  • Reorientation and Vibrational Relaxation as Line Broadening Factors in Vibrational Spectroscopy

    Laurence A. Nafie;Warner L. Peticolas

  • Tripeptides adopt stable structures in water. A combined polarized visible Raman, FTIR, and VCD spectroscopy study.

    Fatma Eker;Xiaolin Cao;Laurence Nafie;Reinhard Schweitzer-Stenner

  • A confidence level algorithm for the determination of absolute configuration using vibrational circular dichroism or Raman optical activity.

    Elke Debie;Ewoud De Gussem;Ewoud De Gussem;Rina K. Dukor;Wouter Herrebout

  • Is supramolecular filament chirality the underlying cause of major morphology differences in amyloid fibrils

    Dmitry Kurouski;Xuefang Lu;Ludmila Popova;William Wan

  • Vibronic coupling theory of infrared vibrational transitions

    Laurence A. Nafie;Teresa B. Freedman

  • Vibrational circular dichroism of 2,2,2-trifluoro-1-phenylethanol

    L. A. Nafie;J. C. Cheng;P. J. Stephens

  • Quantum Theory of the Intensities of Molecular Vibrational Spectra

    Warner L. Peticolas;Laurence Nafie;Paul Stein;Bruno Fanconi

  • Vibrational circular dichroism shows unusual sensitivity to protein fibril formation and development in solution.

    Shengli Ma;Xiaolin Cao;Mimi Mak;Adeola Sadik

  • Theory of resonance Raman optical activity: the single electronic state limit

    Laurence A Nafie

  • Direct observation and pH control of reversed supramolecular chirality in insulin fibrils by vibrational circular dichroism.

    Dmitry Kurouski;Rosina A. Lombardi;Rina K. Dukor;Igor K. Lednev

  • Role of hydration in determining the structure and vibrational spectra of L-alanine and N-acetyl L-alanine N′-methylamide in aqueous solution: a combined theoretical and experimental approach

    K. J. Jalkanen;I. M. Degtyarenko;R. M. Nieminen;X. Cao

  • Vibrational circular dichroism in amino acids and peptides. 4. Vibrational analysis, assignments, and solution-phase Raman spectra of deuterated isotopomers of alanine

    Max Diem;Prasad L. Polavarapu;Mohammedreza Oboodi;Laurence A. Nafie

  • Adiabatic molecular properties beyond the Born–Oppenheimer approximation. Complete adiabatic wave functions and vibrationally induced electronic current density

    Laurence A. Nafie

  • The conformation of tetraalanine in water determined by polarized Raman, FT-IR, and VCD spectroscopy.

    Reinhard Schweitzer-Stenner;Fatma Eker;Kai Griebenow;Xiaolin Cao

  • Dual polarization modulation: A real-time, spectral-multiplex separation of circular dichroism from linear birefringence spectral intensities

    Laurence A. Nafie

  • Preferred peptide backbone conformations in the unfolded state revealed by the structure analysis of alanine-based (AXA) tripeptides in aqueous solution

    Fatma Eker;Kai Griebenow;Xiaolin Cao;Laurence A. Nafie

Frequent Co-Authors

Prasad L. Polavarapu
Prasad L. Polavarapu Vanderbilt University
Max Diem
Max Diem Northeastern University
Igor K. Lednev
Igor K. Lednev University at Albany, State University of New York
Warner L. Peticolas
Warner L. Peticolas University of Oregon
Lutz Hecht
Lutz Hecht University of Glasgow
James C. Dabrowiak
James C. Dabrowiak Syracuse University
Kai Griebenow
Kai Griebenow University of Puerto Rico at Río Piedras
Vanderlan da Silva Bolzani
Vanderlan da Silva Bolzani Sao Paulo State University
Philip J. Stephens
Philip J. Stephens University of Southern California

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