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D-Index & Metrics

Microbiology

D-Index
59
Citations
10468
World Ranking
3315
National Ranking
1307

Overview

Jean C. Lee is affiliated with Brigham and Women's Hospital in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology, Microbiology, Infectious Diseases, Pulmonary and Respiratory Medicine, and Public Health, Environmental and Occupational Health.

The scientist's work addresses several main research topics, including:

  • Antimicrobial Resistance in Staphylococcus
  • Bacterial Infections and Vaccines
  • Bacterial biofilms and quorum sensing
  • Antimicrobial Peptides and Activities
  • Biochemical and Structural Characterization
  • HIV/AIDS Research and Interventions
  • Electrolyte and hormonal disorders

Jean C. Lee has published research in a range of venues, frequently contributing to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Journal of the American Society of Nephrology
  • American Journal of Transplantation
  • Proceedings of the National Academy of Sciences

Recent notable publications include:

  • "Orchestration of human macrophage NLRP3 inflammasome activation by Staphylococcus aureus extracellular vesicles," 2020, Proceedings of the National Academy of Sciences
  • "Staphylococcus aureus Extracellular Vesicles: A Story of Toxicity and the Stress of 2020," 2021, Toxins
  • "On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis," 2023, Cell Host & Microbe
  • "Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer," 2020, Oncogene
  • "IBT-V02: A Multicomponent Toxoid Vaccine Protects Against Primary and Secondary Skin Infections Caused by Staphylococcus aureus," 2021, Frontiers in Immunology

The scientist frequently collaborates with a group of coauthors whose most frequent collaborators include Heiko Yang, Marshall L. Stoller, Xiaogang Wang, Nicholas Higgins, and Nicolás Meyer.

Best Publications

  • Staphylococcus aureus Capsular Polysaccharides

    Katherine O'Riordan;Jean C. Lee

  • Broadly Protective Vaccine for Staphylococcus aureus Based on an in Vivo-Expressed Antigen

    David McKenney;Kimberly L. Pouliot;Ying Wang;Vivek Murthy

  • Whole-Genome Sequencing of Staphylococcus haemolyticus Uncovers the Extreme Plasticity of Its Genome and the Evolution of Human-Colonizing Staphylococcal Species

    Fumihiko Takeuchi;Shinya Watanabe;Tadashi Baba;Harumi Yuzawa

  • Staphylococcus aureus Serotype 5 Capsular Polysaccharide Is Antiphagocytic and Enhances Bacterial Virulence in a Murine Bacteremia Model

    Manoj Thakker;Jin-Sir Park;Vincent Carey;Jean C. Lee

  • Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform

    Xiaogang Wang;Christopher D. Thompson;Christopher Weidenmaier;Jean C. Lee

  • Comparison of virulence in community-associated methicillin-resistant Staphylococcus aureus pulsotypes USA300 and USA400 in a rat model of pneumonia.

    Christopher P. Montgomery;Susan Boyle-Vavra;Patricia V. Adem;Jean C. Lee

  • Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model.

    Adam C. Schaffer;Robert M. Solinga;Jordan Cocchiaro;Marta Portoles

  • NorB, an Efflux Pump in Staphylococcus aureus Strain MW2, Contributes to Bacterial Fitness in Abscesses

    Yanpeng Ding;Yoshikuni Onodera;Jean C. Lee;David C. Hooper

  • The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes

    Subrata Sau;Navneet Bhasin;Elisabeth R. Wann;Jean C. Lee

  • Protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide in a modified model of endocarditis in rats.

    Jean C. Lee;Jin-Sir Park;Sara E. Shepherd;Vincent Carey

  • Structural rationale for the modulation of abscess formation by Staphylococcus aureus capsular polysaccharides

    Arthur O. Tzianabos;Julia Y. Wang;Jean C. Lee

  • Vaccination and passive immunisation against Staphylococcus aureus

    Adam C. Schaffer;Jean C. Lee

  • Development and Characterization of a Staphylococcus Aureus Nasal Colonization Model in Mice

    Kevin B. Kiser;Jean M. Cantey-Kiser;Jean C. Lee

  • Capsule Production and Growth Phase Influence Binding of Complement to Staphylococcus aureus

    K. M. Cunnion;J. C. Lee;M. M. Frank

  • Orchestration of human macrophage NLRP3 inflammasome activation by Staphylococcus aureus extracellular vesicles.

    Xiaogang Wang;William J. Eagen;Jean C. Lee

  • The Effectiveness of the Controlled Release of Gentamicin from Polyelectrolyte Multilayers in the Treatment of Staphylococcus aureus Infection in a Rabbit Bone Model

    Joshua Seth Moskowitz;Michael R. Blaisse;Raymond E. Samuel;Hu-Ping Hsu;Hu-Ping Hsu

  • Staphylococcus aureus Strains That Express Serotype 5 or Serotype 8 Capsular Polysaccharides Differ in Virulence

    Andrew Watts;Danbing Ke;Qun Wang;Anil Pillay

  • Reversion of the glycopeptide resistance phenotype in Staphylococcus aureus clinical isolates

    Susan Boyle-Vavra;Sarah K. Berke;Jean C. Lee;Robert S. Daum

  • Adherence of Staphylococcus aureus to endothelial cells: influence of capsular polysaccharide, global regulator agr, and bacterial growth phase.

    Petra Pöhlmann-Dietze;Martina Ulrich;Kevin B. Kiser;Gerd Döring

  • Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection

    Mathias Schmelcher;Yang Shen;Daniel C. Nelson;Marcel R. Eugster

Frequent Co-Authors

Gerald B. Pier
Gerald B. Pier Brigham and Women's Hospital
Christiane Wolz
Christiane Wolz University of Tübingen
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
Barbara C. Kahl
Barbara C. Kahl University of Münster
Donald A. Goldmann
Donald A. Goldmann Boston Children's Hospital
Georg Peters
Georg Peters University of Münster
Timothy J. Foster
Timothy J. Foster Campden BRI (United Kingdom)
Susan Boyle-Vavra
Susan Boyle-Vavra University of Chicago
Gerd Döring
Gerd Döring University of Tübingen
M. Javad Aman
M. Javad Aman Integrated BioTherapeutics (United States)

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