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Biology and Biochemistry

D-Index
63
Citations
11017
World Ranking
10456
National Ranking
709

Overview

Ituro Inoue is affiliated with the National Institute of Genetics in Japan and specializes in research at the intersection of biochemistry, genetics, and molecular biology, with a substantive focus on medical applications. Their scholarly output spans 39 publications related to these main fields, with 33 additional works concentrated within medicine.

The scientist's subfields of study demonstrate a detailed engagement with key areas including molecular biology, genetics, reproductive medicine, cancer research, and immunology. This breadth reflects a research pattern that integrates fundamental biological mechanisms with disease-specific investigations.

Key research topics addressed by Ituro Inoue include ovarian cancer diagnosis and treatment, RNA modifications and cancer, cancer genomics and diagnostics, Moyamoya disease diagnosis and treatment, chromatin remodeling and cancer, epigenetics and DNA methylation, and cancer-related molecular mechanisms research. These areas highlight a strong emphasis on cancer biology and molecular mechanisms influencing disease pathology.

Their publication record lists several recent papers exemplifying this focus:

  • APOBEC: A molecular driver in cervical cancer pathogenesis, 2020, Cancer Letters
  • XCL1 expression correlates with CD8-positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary, 2020, Oncogene
  • Clonal lineage from normal endometrium to ovarian clear cell carcinoma through ovarian endometriosis, 2020, Cancer Science
  • Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium, 2022, Nature Communications
  • ARID1A protein expression is retained in ovarian endometriosis with ARID1A loss-of-function mutations: implication for the two-hit hypothesis, 2020, Scientific Reports

Frequent co-authors collaborating with Ituro Inoue include Hirofumi Nakaoka, Kosuke Yoshihara, Takayuki Enomoto, Sundaramoorthy Revathidevi, and Arasambattu Kannan Munirajan. These collaborations have contributed to a body of work that advances understanding in cancer biology and genetic mechanisms.

Among publication venues, the scientist has contributed most frequently to Scientific Reports and Research Square, followed by Cancer Science, Journal of Human Genetics, and bioRxiv (Cold Spring Harbor Laboratory). This dissemination pattern reflects engagement with both peer-reviewed journals and preprint platforms.

Best Publications

  • Clonal Expansion and Diversification of Cancer-Associated Mutations in Endometriosis and Normal Endometrium

    Kazuaki Suda;Hirofumi Nakaoka;Kosuke Yoshihara;Tatsuya Ishiguro

  • Genome-wide association study of intracranial aneurysm identifies three new risk loci

    Katsuhito Yasuno;Kaya Bilguvar;Philippe Bijlenga;Siew Kee Low

  • Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter.

    Yasuo Aihara;Hirosato Mashima;Hideaki Onda;Setsuji Hisano

  • Susceptibility loci for intracranial aneurysm in European and Japanese populations.

    Kaya Bilguvar;Katsuhito Yasuno;Mika Niemelä;Ynte M Ruigrok

  • Next-generation sequencing: impact of exome sequencing in characterizing Mendelian disorders.

    Bahareh Rabbani;Nejat Mahdieh;Kazuyoshi Hosomichi;Hirofumi Nakaoka

  • Regulation of the hepatitis C virus genome replication by miR-199a

    Yoshiki Murakami;Hussein H. Aly;Atsushi Tajima;Ituro Inoue

  • Identification of Genes Differentially Expressed in Canine Vasospastic Cerebral Arteries after Subarachnoid Hemorrhage

    Hideaki Onda;Hidetoshi Kasuya;Kintomo Takakura;Tomokatsu Hori

  • Gene expression profiling of advanced‐stage serous ovarian cancers distinguishes novel subclasses and implicates ZEB2 in tumor progression and prognosis

    Kosuke Yoshihara;Atsushi Tajima;Dai Komata;Tadashi Yamamoto

  • The impact of next-generation sequencing technologies on HLA research.

    Kazuyoshi Hosomichi;Takashi Shiina;Atsushi Tajima;Ituro Inoue

  • High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway

    Kosuke Yoshihara;Tatsuhiko Tsunoda;Daichi Shigemizu;Hiroyuki Fujiwara

  • Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

    Hirotaka Matsuo;Ken Yamamoto;Hirofumi Nakaoka;Akiyoshi Nakayama

  • Integration of hepatitis B virus DNA into the myeloid/lymphoid or mixed-lineage leukemia (MLL4) gene and rearrangements of MLL4 in human hepatocellular carcinoma.

    Kenichi Saigo;Kenichi Yoshida;Ryuji Ikeda;Yoshiko Sakamoto

  • Gene expression profile for predicting survival in advanced-stage serous ovarian cancer across two independent datasets.

    Kosuke Yoshihara;Atsushi Tajima;Tetsuro Yahata;Shoji Kodama

  • Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses.

    Jumpei Ito;Jumpei Ito;Ryota Sugimoto;Hirofumi Nakaoka;Hirofumi Nakaoka;Shiro Yamada

  • Natural selection and population history in the human angiotensinogen gene (AGT): 736 complete AGT sequences in chromosomes from around the world.

    Toshiaki Nakajima;Stephen Wooding;Takuro Sakagami;Mitsuru Emi

  • Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk

    Katsuhito Yasuno;Mehmet Bakırcıoğlu;Siew-Kee Low;Kaya Bilgüvar

  • Genome-wide Linkage Analysis of Mandibular Prognathism in Korean and Japanese Patients

    T. Yamaguchi;S.B. Park;A. Narita;K. Maki

  • Genome-Wide Expression of Azoospermia Testes Demonstrates a Specific Profile and Implicates ART3 in Genetic Susceptibility

    Hiroyuki Okada;Atsushi Tajima;Kazuyoshi Shichiri;Atsushi Tanaka

  • APOBEC: A molecular driver in cervical cancer pathogenesis.

    Sundaramoorthy Revathidevi;Avaniyapuram Kannan Murugan;Hirofumi Nakaoka;Ituro Inoue

  • Regulation of Geminin and Cdt1 expression by E2F transcription factors.

    Kenichi Yoshida;Ituro Inoue

Frequent Co-Authors

Atsushi Tajima
Atsushi Tajima Kanazawa University
Hidetoshi Inoko
Hidetoshi Inoko Tokai University
Ken Yamamoto
Ken Yamamoto Kurume University
Akira Hata
Akira Hata Chiba University
Naruya Saitou
Naruya Saitou National Institute of Genetics
Gabriel J.E. Rinkel
Gabriel J.E. Rinkel Utrecht University
Katsushi Tokunaga
Katsushi Tokunaga University of Tokyo
Yukinori Okada
Yukinori Okada Osaka University
Yusuke Nakamura
Yusuke Nakamura National Institutes of Biomedical Innovation, Health and Nutrition

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