Isabella L. Karle

Research.com Recognitions

• 1995 - US President's National Medal of Science "For the development and applicatiom of a method for determining essentially equal-atom crystal and molecular structures by x-ray analysis, thereby having a profound effect on the practice of organic and biological chemistry.", Awarded by President Clinton at a White House ceremony on October 18, 1995.
• 1995 - NAS Award in Chemical Sciences, National Academy of Sciences (US) For her development of a method for determining essentially equal-atom crystal and molecular structures by X-ray analysis, thereby profoundly affecting the practice of chemistry.
• 1988 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences For her eminent crystallographic investigations of complicated natural products.
• 1978 - Member of the National Academy of Sciences
• 1976 - Garvan–Olin Medal, American Chemical Society (ACS)

Overview

Best Publications

• Structural characteristics of .alpha.-helical peptide molecules containing Aib residues

  Isabella L. Karle;Padmanabhan Balaram

  1417
  Citations

• β-Peptide Foldamers: Robust Helix Formation in a New Family of β-Amino Acid Oligomers

  Daniel H. Appella;Laurie A. Christianson;Isabella L. Karle;and Douglas R. Powell

  960
  Citations

• The symbolic addition procedure for phase determination for centrosymmetric and non‐centrosymmetric crystals

  Unknown

  446
  Citations

• Synthesis and Characterization of trans-2-Aminocyclohexanecarboxylic Acid Oligomers: An Unnatural Helical Secondary Structure and Implications for β-Peptide Tertiary Structure

  Daniel H. Appella;Laurie A. Christianson;Isabella L. Karle;and Douglas R. Powell

  253
  Citations

• A designed beta-hairpin peptide in crystals

  Isabella L Karle;Satish K Awasthi;Padmanabhan Balaram

  222
  Citations

• Internal Motion and Molecular Structure Studies by Electron Diffraction

  Isabella Lugoski Karle;Jerome Karle

  217
  Citations

• pi. Complexation in ion pair bonding. Structure of benzyllithium triethylenediamine

  S. P. Patterman;Isabella L. Karle;G. D. Stucky

  205
  Citations

• Histrionicotoxins: Roentgen-Ray Analysis of the Novel Allenic and Acetylenic Spiroalkaloids Isolated from a Colombian Frog, Dendrobates histrionicus

  John W. Daly;Isabella Karle;Charles W. Myers;Takashi Tokuyama

  197
  Citations

• Aromatic−Aromatic Interactions in Crystal Structures of Helical Peptide Scaffolds Containing Projecting Phenylalanine Residues

  Subrayashastry Aravinda;Narayanaswamy Shamala;Chittaranjan Das;Arumugam Sriranjini

  182
  Citations

• Gephyrotoxins, Histrionicotoxins and Pumiliotoxins from the Neotropical Frog Dendrobates histrionicus†

  J. W. Daly;B. Witkop;T. Tokuyama;T. Nishikawa

  171
  Citations

• Conformation of a 16-residue zervamicin IIA analog peptide containing three different structural features: 3(10)-helix, alpha-helix, and beta-bend ribbon.

  Isabella L Karle;Judith Flippen-Anderson;Muppalla Sukumar;Padmanabhan Balaram

  167
  Citations

• Crystal structure of [Leu1]zervamicin, a membrane ion-channel peptide: implications for gating mechanisms.

  Isabella L Karle;Judith L Flippen-Anderson;Sanjay Agarwalla;Padmanabhan Balaram

  154
  Citations

• ω-Amino Acids in Peptide Design. Crystal Structures and Solution Conformations of Peptide Helices Containing a β-Alanyl-γ-Aminobutyryl Segment

  IL Karle;Animesh Pramanik;Arindam Banerjee;Surajit Bhattacharjya

  153
  Citations

• Conformation of the cyclic tetrapeptide dihydrochlamydocin. Iabu-L-Phe-D-Pro-LX, and experimental values for 3 1 intramolecular hydrogen bonds by X-ray diffraction†

  Judith L. Flippen;Isabella L. Karle

  147
  Citations

• An application of a new phase determination procedure to the structure of cyclo(hexaglycyl)demihydrate

  Unknown

  142
  Citations

• A new class of indolizidine alkaloids from the poison frog, Dendrobates tricolor. X-ray analysis of 8-hydroxy-8-methyl-6-(2'-methylhexylidene)-1-azabicyclo[4.3.0]nonane

  J. W. Daly;T. Tokuyama;T. Fujiwara;R. J. Highet

  140
  Citations

• Crystal structure and conformation of cyclo-(glycylprolylglycyl-D-alanylprolyl) containing 4 .fwdarw. 1 and 3 .fwdarw. 1 intramolecular hydrogen bonds

  Isabella L. Karle

  129
  Citations

• The Structures of Biphenyl, o-Terphenyl and Tetraphenylene1

  Isabella Lugoski Karle;L. O. Brockway

  129
  Citations

• A Persistent Preference for Layer Motifs in Self-Assemblies of Squarates and Hydrogen Squarates by Hydrogen Bonding [X−H···O; X = N, O, or C]: A Crystallographic Study of Five Organic Salts

  Isabella L. Karle;Darshan Ranganathan;V. Haridas

  126
  Citations

• Crystal structure of a versatile organic clathrate. 4-p-Hydroxyphenyl-2,2,4-trimethylchroman (Dianin's compound)

  J. L. Flippen;Jerome Karle;Isabella L. Karle

  118
  Citations

• [Leu5]enkephalin: four cocrystallizing conformers with extended backbones that form an antiparallel β-sheet

  I.L. Karle;J. Karle;D. Mastropaolo;A. Camerman

  117
  Citations

• Crystal structure of the visual chromophores, 11-cis and all-trans retinal.

  R. Gilardi;I. L. Karle;J. Karle;W. Sperling

  115
  Citations

• An application of the symbolic addition method to the structure of l‐arginine dihydrate

  Unknown

  114
  Citations