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D-Index & Metrics

Discipline name D-Index World Ranking National Ranking Publications Citations
Chemistry 70 5983 1825 377 14867

Isabella L. Karle publications per year

The chart shows the history of publications by Isabella L. Karle between 1950 and 2016, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Isabella L. Karle published across 67 years, from 1950 to 2016, averaging 5.6 papers a year. Output peaked at 27 publications in 1970. 1 of the 378 publications appeared in the last two years.

No. of publications
5 10 15 20 25
Bar chart. Horizontal axis: year, 1950 to 2016. Vertical axis: number of publications, 0 to 27. Peak 27 publications in 1970. 1950: 3 publications 1951: 0 publications 1952: 2 publications 1953: 1 publication 1954: 2 publications 1955: 2 publications 1956: 0 publications 1957: 1 publication 1958: 0 publications 1959: 0 publications 1960: 3 publications 1961: 1 publication 1962: 2 publications 1963: 2 publications 1964: 6 publications 1965: 8 publications 1966: 8 publications 1967: 11 publications 1968: 5 publications 1969: 13 publications 1970: 27 publications 1971: 11 publications 1972: 13 publications 1973: 6 publications 1974: 9 publications 1975: 9 publications 1976: 4 publications 1977: 5 publications 1978: 3 publications 1979: 5 publications 1980: 5 publications 1981: 10 publications 1982: 4 publications 1983: 6 publications 1984: 7 publications 1985: 5 publications 1986: 4 publications 1987: 4 publications 1988: 13 publications 1989: 8 publications 1990: 9 publications 1991: 7 publications 1992: 11 publications 1993: 4 publications 1994: 6 publications 1995: 2 publications 1996: 11 publications 1997: 5 publications 1998: 8 publications 1999: 9 publications 2000: 6 publications 2001: 12 publications 2002: 8 publications 2003: 4 publications 2004: 3 publications 2005: 5 publications 2006: 2 publications 2007: 6 publications 2008: 4 publications 2009: 26 publications 2010: 0 publications 2011: 0 publications 2012: 1 publication 2013: 0 publications 2014: 0 publications 2015: 0 publications 2016: 1 publication
1950 2016

378 publications in total across all disciplines

View publications per year as a table
Isabella L. Karle: publications per year, 1950 to 2016
Year Publications
1950 3
1951 0
1952 2
1953 1
1954 2
1955 2
1956 0
1957 1
1958 0
1959 0
1960 3
1961 1
1962 2
1963 2
1964 6
1965 8
1966 8
1967 11
1968 5
1969 13
1970 27
1971 11
1972 13
1973 6
1974 9
1975 9
1976 4
1977 5
1978 3
1979 5
1980 5
1981 10
1982 4
1983 6
1984 7
1985 5
1986 4
1987 4
1988 13
1989 8
1990 9
1991 7
1992 11
1993 4
1994 6
1995 2
1996 11
1997 5
1998 8
1999 9
2000 6
2001 12
2002 8
2003 4
2004 3
2005 5
2006 2
2007 6
2008 4
2009 26
2010 0
2011 0
2012 1
2013 0
2014 0
2015 0
2016 1
Total 378
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Isabella L. Karle publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Isabella L. Karle sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 361–380 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 377 publications — 77th percentile

77% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522 377
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Isabella L. Karle D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Isabella L. Karle sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 70–71 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 70 D-Index — 68th percentile

68% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646 70
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
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Research.com Recognitions

  • 1995 - US President's National Medal of Science "For the development and applicatiom of a method for determining essentially equal-atom crystal and molecular structures by x-ray analysis, thereby having a profound effect on the practice of organic and biological chemistry.", Awarded by President Clinton at a White House ceremony on October 18, 1995.
  • 1995 - NAS Award in Chemical Sciences, National Academy of Sciences (US) For her development of a method for determining essentially equal-atom crystal and molecular structures by X-ray analysis, thereby profoundly affecting the practice of chemistry.
  • 1988 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences For her eminent crystallographic investigations of complicated natural products.
  • 1978 - Member of the National Academy of Sciences
  • 1976 - Garvan–Olin Medal, American Chemical Society (ACS)

Overview

Isabella L. Karle was a scientist affiliated with the United States Naval Research Laboratory in the United States. Their work primarily focused on methods for determining crystal and molecular structures by X-ray analysis, contributing to the fields of organic and biological chemistry.

Throughout their career, they received several notable awards, reflecting their contributions to chemistry and crystallography. These awards include:

  • US President's National Medal of Science (1995) - Awarded "for the development and application of a method for determining essentially equal-atom crystal and molecular structures by X-ray analysis, thereby having a profound effect on the practice of organic and biological chemistry," presented by President Clinton at a White House ceremony on October 18, 1995.
  • NAS Award in Chemical Sciences, National Academy of Sciences (US) (1995) - For the development of a method that profoundly affected the practice of chemistry through X-ray structural determination.
  • Gregori Aminoff Prize, Royal Swedish Academy of Sciences (1988) - For crystallographic investigations of complicated natural products.
  • Member of the National Academy of Sciences (1978).
  • Garvan-Olin Medal, American Chemical Society (ACS) (1976).

Isabella L. Karle's contributions had a significant impact on the practice of organic and biological chemistry through advancements in X-ray crystallography. The methods they developed allowed for the determination of molecular structures composed of essentially equal atoms, which has been influential in various chemical analyses.

Best Publications

  • Structural characteristics of .alpha.-helical peptide molecules containing Aib residues

    Isabella L. Karle;Padmanabhan Balaram

  • β-Peptide Foldamers: Robust Helix Formation in a New Family of β-Amino Acid Oligomers

    Daniel H. Appella;Laurie A. Christianson;Isabella L. Karle;and Douglas R. Powell

  • The symbolic addition procedure for phase determination for centrosymmetric and non‐centrosymmetric crystals

    Unknown

  • Synthesis and Characterization of trans-2-Aminocyclohexanecarboxylic Acid Oligomers: An Unnatural Helical Secondary Structure and Implications for β-Peptide Tertiary Structure

    Daniel H. Appella;Laurie A. Christianson;Isabella L. Karle;and Douglas R. Powell

  • A designed beta-hairpin peptide in crystals

    Isabella L Karle;Satish K Awasthi;Padmanabhan Balaram

  • Internal Motion and Molecular Structure Studies by Electron Diffraction

    Isabella Lugoski Karle;Jerome Karle

  • pi. Complexation in ion pair bonding. Structure of benzyllithium triethylenediamine

    S. P. Patterman;Isabella L. Karle;G. D. Stucky

  • Histrionicotoxins: Roentgen-Ray Analysis of the Novel Allenic and Acetylenic Spiroalkaloids Isolated from a Colombian Frog, Dendrobates histrionicus

    John W. Daly;Isabella Karle;Charles W. Myers;Takashi Tokuyama

  • Aromatic−Aromatic Interactions in Crystal Structures of Helical Peptide Scaffolds Containing Projecting Phenylalanine Residues

    Subrayashastry Aravinda;Narayanaswamy Shamala;Chittaranjan Das;Arumugam Sriranjini

  • Gephyrotoxins, Histrionicotoxins and Pumiliotoxins from the Neotropical Frog Dendrobates histrionicus†

    J. W. Daly;B. Witkop;T. Tokuyama;T. Nishikawa

  • Conformation of a 16-residue zervamicin IIA analog peptide containing three different structural features: 3(10)-helix, alpha-helix, and beta-bend ribbon.

    Isabella L Karle;Judith Flippen-Anderson;Muppalla Sukumar;Padmanabhan Balaram

  • Crystal structure of [Leu1]zervamicin, a membrane ion-channel peptide: implications for gating mechanisms.

    Isabella L Karle;Judith L Flippen-Anderson;Sanjay Agarwalla;Padmanabhan Balaram

  • ω-Amino Acids in Peptide Design. Crystal Structures and Solution Conformations of Peptide Helices Containing a β-Alanyl-γ-Aminobutyryl Segment

    IL Karle;Animesh Pramanik;Arindam Banerjee;Surajit Bhattacharjya

  • Conformation of the cyclic tetrapeptide dihydrochlamydocin. Iabu-L-Phe-D-Pro-LX, and experimental values for 3 1 intramolecular hydrogen bonds by X-ray diffraction†

    Judith L. Flippen;Isabella L. Karle

  • An application of a new phase determination procedure to the structure of cyclo(hexaglycyl)demihydrate

    Unknown

  • A new class of indolizidine alkaloids from the poison frog, Dendrobates tricolor. X-ray analysis of 8-hydroxy-8-methyl-6-(2'-methylhexylidene)-1-azabicyclo[4.3.0]nonane

    J. W. Daly;T. Tokuyama;T. Fujiwara;R. J. Highet

  • Crystal structure and conformation of cyclo-(glycylprolylglycyl-D-alanylprolyl) containing 4 .fwdarw. 1 and 3 .fwdarw. 1 intramolecular hydrogen bonds

    Isabella L. Karle

  • The Structures of Biphenyl, o-Terphenyl and Tetraphenylene1

    Isabella Lugoski Karle;L. O. Brockway

  • A Persistent Preference for Layer Motifs in Self-Assemblies of Squarates and Hydrogen Squarates by Hydrogen Bonding [X−H···O; X = N, O, or C]: A Crystallographic Study of Five Organic Salts

    Isabella L. Karle;Darshan Ranganathan;V. Haridas

  • Crystal structure of a versatile organic clathrate. 4-p-Hydroxyphenyl-2,2,4-trimethylchroman (Dianin's compound)

    J. L. Flippen;Jerome Karle;Isabella L. Karle

  • [Leu5]enkephalin: four cocrystallizing conformers with extended backbones that form an antiparallel β-sheet

    I.L. Karle;J. Karle;D. Mastropaolo;A. Camerman

  • Crystal structure of the visual chromophores, 11-cis and all-trans retinal.

    R. Gilardi;I. L. Karle;J. Karle;W. Sperling

  • An application of the symbolic addition method to the structure of l‐arginine dihydrate

    Unknown

Frequent Co-Authors

Padmanabhan Balaram
Padmanabhan Balaram Indian Institute of Science
Judith L. Flippen-Anderson
Judith L. Flippen-Anderson United States Naval Research Laboratory
Bernhard Witkop
Bernhard Witkop National Institutes of Health
John W. Daly
John W. Daly National Institutes of Health
Rolf Huisgen
Rolf Huisgen Ludwig-Maximilians-Universität München
Theodor Wieland
Theodor Wieland Max Planck Society
Clifford George
Clifford George United States Naval Research Laboratory
Arindam Banerjee
Arindam Banerjee Indian Association for the Cultivation of Science
Ray J. Butcher
Ray J. Butcher Howard University
Zakya H. Kafafi
Zakya H. Kafafi Lehigh University

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