World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
70
Citations
14867
World Ranking
5983
National Ranking
1825

Isabella L. Karle publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Isabella L. Karle sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 377 publications — 77th percentile

77% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Isabella L. Karle D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Isabella L. Karle sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 70 D-Index — 68th percentile

68% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 1995 - US President's National Medal of Science "For the development and applicatiom of a method for determining essentially equal-atom crystal and molecular structures by x-ray analysis, thereby having a profound effect on the practice of organic and biological chemistry.", Awarded by President Clinton at a White House ceremony on October 18, 1995.
  • 1995 - NAS Award in Chemical Sciences, National Academy of Sciences (US) For her development of a method for determining essentially equal-atom crystal and molecular structures by X-ray analysis, thereby profoundly affecting the practice of chemistry.
  • 1988 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences For her eminent crystallographic investigations of complicated natural products.
  • 1978 - Member of the National Academy of Sciences
  • 1976 - Garvan–Olin Medal, American Chemical Society (ACS)

Overview

Isabella L. Karle was a scientist affiliated with the United States Naval Research Laboratory in the United States. Their work primarily focused on methods for determining crystal and molecular structures by X-ray analysis, contributing to the fields of organic and biological chemistry.

Throughout their career, they received several notable awards, reflecting their contributions to chemistry and crystallography. These awards include:

  • US President's National Medal of Science (1995) - Awarded "for the development and application of a method for determining essentially equal-atom crystal and molecular structures by X-ray analysis, thereby having a profound effect on the practice of organic and biological chemistry," presented by President Clinton at a White House ceremony on October 18, 1995.
  • NAS Award in Chemical Sciences, National Academy of Sciences (US) (1995) - For the development of a method that profoundly affected the practice of chemistry through X-ray structural determination.
  • Gregori Aminoff Prize, Royal Swedish Academy of Sciences (1988) - For crystallographic investigations of complicated natural products.
  • Member of the National Academy of Sciences (1978).
  • Garvan-Olin Medal, American Chemical Society (ACS) (1976).

Isabella L. Karle's contributions had a significant impact on the practice of organic and biological chemistry through advancements in X-ray crystallography. The methods they developed allowed for the determination of molecular structures composed of essentially equal atoms, which has been influential in various chemical analyses.

Best Publications

  • Structural characteristics of .alpha.-helical peptide molecules containing Aib residues

    Isabella L. Karle;Padmanabhan Balaram

  • β-Peptide Foldamers: Robust Helix Formation in a New Family of β-Amino Acid Oligomers

    Daniel H. Appella;Laurie A. Christianson;Isabella L. Karle;and Douglas R. Powell

  • The symbolic addition procedure for phase determination for centrosymmetric and non‐centrosymmetric crystals

    Unknown

  • Synthesis and Characterization of trans-2-Aminocyclohexanecarboxylic Acid Oligomers: An Unnatural Helical Secondary Structure and Implications for β-Peptide Tertiary Structure

    Daniel H. Appella;Laurie A. Christianson;Isabella L. Karle;and Douglas R. Powell

  • A designed beta-hairpin peptide in crystals

    Isabella L Karle;Satish K Awasthi;Padmanabhan Balaram

  • Internal Motion and Molecular Structure Studies by Electron Diffraction

    Isabella Lugoski Karle;Jerome Karle

  • pi. Complexation in ion pair bonding. Structure of benzyllithium triethylenediamine

    S. P. Patterman;Isabella L. Karle;G. D. Stucky

  • Histrionicotoxins: Roentgen-Ray Analysis of the Novel Allenic and Acetylenic Spiroalkaloids Isolated from a Colombian Frog, Dendrobates histrionicus

    John W. Daly;Isabella Karle;Charles W. Myers;Takashi Tokuyama

  • Aromatic−Aromatic Interactions in Crystal Structures of Helical Peptide Scaffolds Containing Projecting Phenylalanine Residues

    Subrayashastry Aravinda;Narayanaswamy Shamala;Chittaranjan Das;Arumugam Sriranjini

  • Gephyrotoxins, Histrionicotoxins and Pumiliotoxins from the Neotropical Frog Dendrobates histrionicus†

    J. W. Daly;B. Witkop;T. Tokuyama;T. Nishikawa

  • Conformation of a 16-residue zervamicin IIA analog peptide containing three different structural features: 3(10)-helix, alpha-helix, and beta-bend ribbon.

    Isabella L Karle;Judith Flippen-Anderson;Muppalla Sukumar;Padmanabhan Balaram

  • Crystal structure of [Leu1]zervamicin, a membrane ion-channel peptide: implications for gating mechanisms.

    Isabella L Karle;Judith L Flippen-Anderson;Sanjay Agarwalla;Padmanabhan Balaram

  • ω-Amino Acids in Peptide Design. Crystal Structures and Solution Conformations of Peptide Helices Containing a β-Alanyl-γ-Aminobutyryl Segment

    IL Karle;Animesh Pramanik;Arindam Banerjee;Surajit Bhattacharjya

  • Conformation of the cyclic tetrapeptide dihydrochlamydocin. Iabu-L-Phe-D-Pro-LX, and experimental values for 3 1 intramolecular hydrogen bonds by X-ray diffraction†

    Judith L. Flippen;Isabella L. Karle

  • An application of a new phase determination procedure to the structure of cyclo(hexaglycyl)demihydrate

    Unknown

  • A new class of indolizidine alkaloids from the poison frog, Dendrobates tricolor. X-ray analysis of 8-hydroxy-8-methyl-6-(2'-methylhexylidene)-1-azabicyclo[4.3.0]nonane

    J. W. Daly;T. Tokuyama;T. Fujiwara;R. J. Highet

  • Crystal structure and conformation of cyclo-(glycylprolylglycyl-D-alanylprolyl) containing 4 .fwdarw. 1 and 3 .fwdarw. 1 intramolecular hydrogen bonds

    Isabella L. Karle

  • The Structures of Biphenyl, o-Terphenyl and Tetraphenylene1

    Isabella Lugoski Karle;L. O. Brockway

  • A Persistent Preference for Layer Motifs in Self-Assemblies of Squarates and Hydrogen Squarates by Hydrogen Bonding [X−H···O; X = N, O, or C]: A Crystallographic Study of Five Organic Salts

    Isabella L. Karle;Darshan Ranganathan;V. Haridas

  • Crystal structure of a versatile organic clathrate. 4-p-Hydroxyphenyl-2,2,4-trimethylchroman (Dianin's compound)

    J. L. Flippen;Jerome Karle;Isabella L. Karle

  • [Leu5]enkephalin: four cocrystallizing conformers with extended backbones that form an antiparallel β-sheet

    I.L. Karle;J. Karle;D. Mastropaolo;A. Camerman

  • Crystal structure of the visual chromophores, 11-cis and all-trans retinal.

    R. Gilardi;I. L. Karle;J. Karle;W. Sperling

  • An application of the symbolic addition method to the structure of l‐arginine dihydrate

    Unknown

Frequent Co-Authors

Padmanabhan Balaram
Padmanabhan Balaram Indian Institute of Science
Judith L. Flippen-Anderson
Judith L. Flippen-Anderson United States Naval Research Laboratory
Bernhard Witkop
Bernhard Witkop National Institutes of Health
John W. Daly
John W. Daly National Institutes of Health
Rolf Huisgen
Rolf Huisgen Ludwig-Maximilians-Universität München
Theodor Wieland
Theodor Wieland Max Planck Society
Clifford George
Clifford George United States Naval Research Laboratory
Arindam Banerjee
Arindam Banerjee Indian Association for the Cultivation of Science
Ray J. Butcher
Ray J. Butcher Howard University
Zakya H. Kafafi
Zakya H. Kafafi Lehigh University

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