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Biology and Biochemistry

D-Index
47
Citations
8754
World Ranking
18676
National Ranking
653

Overview

Dwayne D. Hegedus is primarily affiliated with Agriculture and Agriculture-Food Canada in Canada. Their research intersects the fields of Agricultural and Biological Sciences as well as Biochemistry, Genetics and Molecular Biology, with a robust concentration on plant and insect science.

Their subfields of study include Plant Science, Molecular Biology, Insect Science, Cellular and Molecular Neuroscience, and Biochemistry. The main topics addressed throughout their work cover:

  • Insect Resistance and Genetics
  • Insect-Plant Interactions and Control
  • Plant pathogens and resistance mechanisms
  • Neurobiology and Insect Physiology Research
  • Lipid metabolism and biosynthesis
  • Invertebrate Immune Response Mechanisms
  • Insect and Pesticide Research

Hegedus has co-authored frequently with several researchers, including:

  • Cathy Coutu
  • Umut Toprak
  • Cansu Doğan
  • Gözde Güney
  • Martin A. Erlandson

Their body of work is published across various venues, with multiple papers appearing in:

  • Archives of Insect Biochemistry and Physiology
  • Insect Biochemistry and Molecular Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Applied Entomology
  • BMC Biology

Some recent publications include:

  • "A journey into the world of insect lipid metabolism" (2020) in Archives of Insect Biochemistry and Physiology
  • "A look into Colorado potato beetle lipid metabolism through the lens of lipid storage droplet proteins" (2020) in Insect Biochemistry and Molecular Biology
  • "Horizontally transmitted parasitoid killing factor shapes insect defense to parasitoids" (2021) in Science
  • "Receptor-Like Kinases BAK1 and SOBIR1 Are Required for Necrotizing Activity of a Novel Group of Sclerotinia sclerotiorum Necrosis-Inducing Effectors" (2020) in Frontiers in Plant Science
  • "Silencing of an ABC transporter, but not a cadherin, decreases the susceptibility of Colorado potato beetle larvae to Bacillus thuringiensis ssp. tenebrionis Cry3Aa toxin" (2021) in Archives of Insect Biochemistry and Physiology

The research focus of Hegedus involves detailed molecular and biochemical analysis related to insect lipid metabolism, insect resistance mechanisms, and plant-pathogen interactions. Their work covers molecular pathways affecting insect physiology and immunity, especially in agricultural pest contexts.

Best Publications

  • RNA interference in Lepidoptera: An overview of successful and unsuccessful studies and implications for experimental design

    Olle Terenius;Alexie Papanicolaou;Alexie Papanicolaou;Jennie S. Garbutt;Ioannis Eleftherianos

  • New Insights into Peritrophic Matrix Synthesis, Architecture, and Function

    Dwayne Hegedus;Martin Erlandson;Cedric Gillott;Umut Toprak

  • Molecular characterization of Brassica napus NAC domain transcriptional activators induced in response to biotic and abiotic stress.

    Dwayne Hegedus;Min Yu;Doug Baldwin;Margaret Gruber

  • Sclerotinia sclerotiorum: When “to be or not to be” a pathogen?

    Dwayne D. Hegedus;S. Roger Rimmer

  • Optimal conditions for the expression of a single-chain antibody (scFv) gene in Pichia pastoris.

    Xianzong Shi;Tammy Karkut;Mahmood Chamankhah;Michelle Alting-Mees

  • The complete genome sequence of the phytopathogenic fungus Sclerotinia sclerotiorum reveals insights into the genome architecture of broad host range pathogens.

    Mark Derbyshire;Matthew Denton-Giles;Dwayne Hegedus;Shirin Seifbarghy

  • Repression of Seed Maturation Genes by a Trihelix Transcriptional Repressor in Arabidopsis Seedlings

    Ming-Jun Gao;Derek J. Lydiate;Xiang Li;Helen Lui

  • pORE: a modular binary vector series suited for both monocot and dicot plant transformation.

    Catherine Coutu;James Brandle;Dan Brown;Kirk Brown

  • A role for seed storage proteins in Arabidopsis seed longevity

    Thu-Phuong Nguyen;Gwendal Cueff;Dwayne D Hegedus;Loïc Rajjou

  • Changes in the Sclerotinia sclerotiorum transcriptome during infection of Brassica napus

    Shirin Seifbarghi;Shirin Seifbarghi;M. Hossein Borhan;Yangdou Wei;Cathy Coutu

  • Patterns of differential gene expression in Brassica napus cultivars infected with Sclerotinia sclerotiorum

    Jianwei Zhao;Jianwei Zhao;Lone Buchwaldt;Samuel Roger Rimmer;Andrew Sharpe

  • De novo sequence assembly of Albugo candida reveals a small genome relative to other biotrophic oomycetes

    Matthew G. Links;Matthew G. Links;E. B. Holub;Rays H. Y. Jiang;Andrew G. Sharpe

  • A journey into the world of insect lipid metabolism.

    Umut Toprak;Dwayne Hegedus;Dwayne Hegedus;Cansu Doğan;Gözde Güney

  • Interaction of Sclerotinia sclerotiorum with Brassica napus: cloning and characterization of endo- and exo-polygalacturonases expressed during saprophytic and parasitic modes.

    Rugang Li;Roger Rimmer;Lone Buchwaldt;Andrew G Sharpe

  • Baculovirus immediate-early promoter-mediated expression of the Zeocin™ resistance gene for use as a dominant selectable marker in Dipteran and Lepidopteran insect cell lines

    Tom A Pfeifer;Dwayne D Hegedus;Thomas A Grigliatti;David A Theilmann

  • The impact of biotechnology on hyphomycetous fungal insect biocontrol agents.

    Dwayne D. Hegedus;George G. Khachatourians

  • Autographa californica Multiple Nucleopolyhedrovirus AC83 is a Per Os Infectivity Factor (PIF) Protein Required for Occlusion-Derived Virus (ODV) and Budded Virus Nucleocapsid Assembly as well as Assembly of the PIF Complex in ODV Envelopes.

    Muhammad Afzal Javed;Siddhartha Biswas;Leslie G. Willis;Stephanie Harris

  • Inoculation of Soil with Plant Growth Promoting Bacteria Producing 1-Aminocyclopropane-1-Carboxylate Deaminase or Expression of the Corresponding acdS Gene in Transgenic Plants Increases Salinity Tolerance in Camelina sativa

    Zohreh Heydarian;Zohreh Heydarian;Min Yu;Margaret Gruber;Bernard R. Glick

  • Midgut proteases from Mamestra configurata (Lepidoptera: Noctuidae) larvae: characterization, cDNA cloning, and expressed sequence tag analysis.

    Dwayne Hegedus;Doug Baldwin;Michael O'Grady;Lorraine Braun

  • Interaction of Sclerotinia sclerotiorum with a resistant Brassica napus cultivar: expressed sequence tag analysis identifies genes associated with fungal pathogenesis.

    Rugang Li;Roger Rimmer;Lone Buchwaldt;Andrew G Sharpe

Frequent Co-Authors

Margaret Y. Gruber
Margaret Y. Gruber Agriculture and Agriculture-Food Canada
Andrew G. Sharpe
Andrew G. Sharpe University of Saskatchewan
Derek J. Lydiate
Derek J. Lydiate Agriculture and Agriculture-Food Canada
Isobel A. P. Parkin
Isobel A. P. Parkin Agriculture and Agriculture-Food Canada
David G. Heckel
David G. Heckel Max Planck Society
Bernard R. Glick
Bernard R. Glick University of Waterloo
Yangdou Wei
Yangdou Wei University of Saskatchewan
Zhangjun Fei
Zhangjun Fei Cornell University
Peiqiang Yu
Peiqiang Yu University of Saskatchewan
Haixia Zhang
Haixia Zhang Peking University

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