David Broadhurst

Best Publications

• Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

  Warwick B Dunn;David Broadhurst;David Broadhurst;Paul Begley;Eva Zelena

  3298
  Citations

• MetaboAnalyst 2.0—a comprehensive server for metabolomic data analysis

  Jianguo Xia;Rupasri Mandal;Igor V. Sinelnikov;David Broadhurst

  1330
  Citations

• A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

  Léonie M. Raamsdonk;Bas Teusink;David Broadhurst;Nianshu Zhang

  1316
  Citations

• Translational biomarker discovery in clinical metabolomics: an introductory tutorial

  Jianguo Xia;David I. Broadhurst;Michael Wilson;David S. Wishart;David S. Wishart

  1048
  Citations

• Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

  Warwick B. Dunn;David I. Broadhurst;Helen J. Atherton;Helen J. Atherton;Royston Goodacre

  1023
  Citations

• Statistical strategies for avoiding false discoveries in metabolomics and related experiments

  David I. Broadhurst;Douglas B. Kell

  946
  Citations

• Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies.

  David Broadhurst;Royston Goodacre;Stacey N. Reinke;Stacey N. Reinke;Julia Kuligowski

  830
  Citations

• Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum.

  Eva Zelena;Warwick B. Dunn;David Broadhurst;Sue Francis-McIntyre

  819
  Citations

• High-throughput classification of yeast mutants for functional genomics using metabolic footprinting

  Jess Allen;Hazel Marie Davey;David Iain Broadhurst;Jim K. Heald

  690
  Citations

• Metabolomics enables precision medicine: "A White Paper, Community Perspective"

  Richard D. Beger;Warwick Dunn;Michael A. Schmidt;Steven S. Gross

  624
  Citations

• Proposed minimum reporting standards for data analysis in metabolomics

  Royston Goodacre;David Broadhurst;Age K. Smilde;Bruce S. Kristal

  515
  Citations

• The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans.

  Warwick B Dunn;Ian D Wilson;Andrew W Nicholls;David Broadhurst

  486
  Citations

• Rapid and quantitative detection of the microbial spoilage of meat by fourier transform infrared spectroscopy and machine learning.

  David Ian Ellis;David Iain Broadhurst;Douglas B. Kell;Jeremy John Rowland

  412
  Citations

• Global metabolic profiling of Escherichia coli cultures: An evaluation of methods for quenching and extraction of intracellular metabolites

  Catherine L. Winder;Warwick B. Dunn;Stephanie Schuler;David Broadhurst

  362
  Citations

• Genetic algorithms as a method for variable selection in multiple linear regression and partial least squares regression, with applications to pyrolysis mass spectrometry

  David Broadhurst;Royston Goodacre;Alun Jones;Jem J Rowland

  357
  Citations

• Metabolic fingerprinting of salt-stressed tomatoes

  Helen Elisabeth Johnson;David Iain Broadhurst;Royston Goodacre;Aileen R. Smith

  313
  Citations

• Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

  Marie Brown;Warwick B. Dunn;P. Dobson;Y. Patel

  311
  Citations

• Molecular phenotyping of a UK population: defining the human serum metabolome.

  Warwick B. Dunn;Wanchang Lin;Wanchang Lin;David Broadhurst;David Broadhurst;Paul Begley;Paul Begley

  259
  Citations

• Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system

  Warwick B Dunn;David Broadhurst;Marie Brown;Philip N Baker

  224
  Citations

• Development and Performance of a Gas Chromatography−Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum

  Paul Begley;Sue Francis-McIntyre;Warwick B. Dunn;David I. Broadhurst

  215
  Citations