World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
32049
World Ranking
3440
National Ranking
1731

Overview

Ani Manichaikul is affiliated with the University of Virginia in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine, with focused subfields including Genetics, Pulmonary and Respiratory Medicine, Molecular Biology, Immunology, and Physiology.

Their recent scholarly contributions include significant papers such as:

  • The power of genetic diversity in genome-wide association studies of lipids (2021, Nature)
  • The Polygenic and Monogenic Basis of Blood Traits and Diseases (2020, Cell)
  • Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations (2020, Cell)
  • Stroke genetics informs drug discovery and risk prediction across ancestries (2022, Nature)
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale (2020, Nature Genetics)

Manichaikul's research interests encompass a variety of topics, including:

  • Genetic Associations and Epidemiology
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Epigenetics and DNA Methylation
  • Genetic Mapping and Diversity in Plants and Animals
  • Bioinformatics and Genomic Networks
  • RNA modifications and cancer
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

The scientist has frequently collaborated with other researchers, including Stephen S. Rich, Jerome I. Rotter, Kent D. Taylor, Bruce M. Psaty, and Jeffrey Haessler. These collaborations reflect an active engagement in large-scale genetic studies and epidemiological research.

Ani Manichaikul's publication record features multiple venues, demonstrating a diverse academic presence. They have published extensively in:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • University of Groningen research database (University of Groningen / Centre for Information Technology)
  • American Journal of Respiratory and Critical Care Medicine
  • Zenodo (CERN European Organization for Nuclear Research)

Best Publications

  • Robust relationship inference in genome-wide association studies

    Ani Manichaikul;Josyf C. Mychaleckyj;Stephen S. Rich;Kathy Daly

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • The polygenic and monogenic basis of blood traits and diseases

    Dragana Vuckovic;Erik L. Bao;Parsa Akbari;Caleb A. Lareau

  • Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

    Ming-Huei Chen;Laura M Raffield;Abdou Mousas;Saori Sakaue

  • Exome-wide association study of plasma lipids in > 300,000 individuals

    Dajiang J Liu;Gina M Peloso;Gina M Peloso;Haojie Yu;Adam S Butterworth;Adam S Butterworth

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Florence Demenais;Florence Demenais;Patricia Margaritte-Jeannin;Patricia Margaritte-Jeannin;Kathleen C. Barnes;William O.C. Cookson

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

    María Soler Artigas;Daan W. Loth;Louise V. Wain;Sina A. Gharib

  • Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.

    Rozenn N. Lemaitre;Toshiko Tanaka;Weihong Tang;Ani Manichaikul

  • Genetic Correlates of Musical Pitch Recognition in Humans

    Dennis Drayna;Ani Manichaikul;Marlies de Lange;Harold Snieder

  • Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

    Brian D. Hobbs;Kim De Jong;Maxime Lamontagne;Yohan Bossé

  • Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

    Phuwanat Sakornsakolpat;Phuwanat Sakornsakolpat;Dmitry Prokopenko;Dmitry Prokopenko;Maxime Lamontagne;Nicola F Reeve

  • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.

    Gina M. Peloso;Paul L. Auer;Joshua C. Bis;Arend Voorman

  • Metabolic network reconstruction of Chlamydomonas offers insight into light‐driven algal metabolism

    Roger L Chang;Lila Ghamsari;Ani Manichaikul;Erik F Y Hom

  • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

    Rainer Malik;Ganesh Chauhan;Matthew Traylor;Muralidharan Sargurupremraj

  • Spectrum of Heart Disease Associated with Murine and Human GATA4 Mutation

    Satish K. Rajagopal;Qing Ma;Dita Obler;Jie Shen

  • A Model Selection Approach for the Identification of Quantitative Trait Loci in Experimental Crosses, Allowing Epistasis

    Ani Manichaikul;Jee Young Moon;Saunak Sen;Brian S Yandell

  • The Polygenic and Monogenic Basis of Blood Traits and Diseases

    Dragana Vuckovic;Dragana Vuckovic;Erik L. Bao;Erik L. Bao;Parsa Akbari;Caleb A. Lareau;Caleb A. Lareau

  • Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Florence Demenais;Patricia Margaritte-Jeannin;Kathleen C. Barnes;William O. C. Cookson

Frequent Co-Authors

Stephen S. Rich
Stephen S. Rich University of Virginia
Bruce M. Psaty
Bruce M. Psaty University of Washington
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
George T. O'Connor
George T. O'Connor Boston University
Yongmei Liu
Yongmei Liu Duke University
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor
R. Graham Barr
R. Graham Barr Columbia University
Myriam Fornage
Myriam Fornage The University of Texas Health Science Center at Houston
Kari E. North
Kari E. North University of North Carolina at Chapel Hill
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam

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