20 Best Clinical Trial Management Software in 2022

20 Best Clinical Trial Management Software in 2022
Imed Bouchrika, Phd by Imed Bouchrika, Phd
Chief Data Scientist & Head of Content

Even before COVID-19 was officially declared a pandemic, clinical trials and research have already been dealing with numerous challenges. These include regulatory mandates, access to patients, managing finances, and the overall complexity of trial designs. While improvements have definitely been implemented in an attempt to simplify the clinical trial process, including the use of laboratory software, its fragmented structure continues to create more loopholes that make clinical trials unnecessarily challenging (Krofah et al., 2021).

This is where clinical trial management software, or CTMS, comes to play a significant role in bringing together the critical components of clinical trials and research, especially in this day and age when remote processes are being utilized more and more in clinical trials. In the list below, we gathered 20 of the best clinical trial management software designed to streamline, speed up, and improve the decision-making process of clinical trial and research operations.

20 Best CTMS Table of Contents in 2022

Key Clinical Trial Management Software Statistics

For years, clinical trial sponsors have relentlessly pursued new avenues to make clinical trials faster and more convenient to patients and physicians with the help of new technology. Come 2020, the COVID-19 crisis has largely contributed to the accelerated adoption of decentralized clinical trial components, which reshape both the  clinical trial environment and experience. Here are some of the relevant statistics that attest to the impact of modern technology on today’s clinical trials:

  • As of June 2022, 32% of registered clinical trial studies are located in the United States (ClinicalTrials.gov, 2022).
  • 57% of clinical trial investigators interacted virtually with patients during the peak of COVID-19 compared to only 9% before the pandemic (Agrawal, et al., 2021).
  • Drug clinical trials that utilized decentralized or virtual components increased by 93% in 2021 (Global Data, 2021).
  • Between 2020 and 2021, mobile applications and devices were being integrated into clinical trial designs as evidenced by the 130% increase in the mention of text messages in clinical trial protocols (Parkins, 2022).
  • 77% of United States-based investigators believe that there will be an increase in the implementation of remote patient monitoring procedures after the pandemic.

Source: McKinsey & Company, 2020

Why is clinical trial management software important?

As with the best scientific data management systems, clinical trial management software solutions provide a solid ground for scientific endeavors. A CTMS provides research sites, teams, and organizations with a specialized comprehensive project management platform that delivers the following benefits:

  • Accessible, accurate, and up-to-date record of data relevant to the organization and the study being conducted.
  • Robust collaboration platform, which enables the members of the team to work together smoothly even from remote locations.
  • Powerful automation tools to boost efficiency, especially when it comes to keeping track of tasks, collecting and updating patient information, progress of study, generating reports, etc.
  • Upholds the integrity of the study by ensuring transparency and compliance with clinical research ethics and execution procedures.

telemedicine during COVID-19

Criteria for Choosing the Top CTMS

Clinical trial sites and research centers are not unfamiliar with the painstaking process involved in trial activities. From keeping track of patient enrollment, finances, to ensuring compliance, etc., each crucial stage takes a lot of time and manpower that affects the speed, efficiency, and even the accuracy of clinical trials. A clinical trial management software provides a single platform that centralizes the critical aspects of the clinical trials and research, which makes it a staple tool in today’s clinical trial operations.

Modern CTMS may offer similar features and functionalities, but there are important factors to consider when it comes to choosing a CTMS that can keep up with the ever-changing environment of clinical trials and research. Some of these criteria are the following:

  • Customizability. A clinical trial management software must offer high levels of customization, particularly in reports and analytics and process automation in order to accommodate the different standard operating procedures, internal policies, and best practices followed by sites, research centers, or organizations.
  • Usability. Although designed to handle the intricate aspects of clinical trial management, a CTMS does not need to be as complex. Having a user-friendly interface is important, especially for sites and organizations that are adopting a CTMS software for the first time.
  • Accessibility. The ability to access a CTMS platform from any research site is another important criteria to consider. Web-based CTMS solutions offer this capability, which helps enhance efficient collaboration among members of the team.
  • Interoperability with other systems. Another factor to consider when choosing a CTMS is its capability to integrate with other tools that your site or organization is already using. This is necessary to ensure smooth automation of processes and secure data migration between platforms.
  • Value for money. The cost of CTMS solutions vary depending on the type of deployment, service packages, add-on fees, etc. While there are CTMS for different budget ranges, it is important to make sure that the features address the needs of the site or organization and the clinical trials they conduct.

Source: Veeva

CTMS Industry Challenges

CTMS is not a new technology—legacy CTMS are now more or less two decades old and are still being used by several research sites and organizations. In fact, 17% of organizations do not have plans to modernize their clinical trial systems and processes, including their CTMS. This, however, presents a significant issue as legacy CTMS’ technology is no longer updated to keep up with the demands of today’s clinical trials and research.

With the majority—if not all—of legacy CTMS deployed on-premise, their capability to support decentralized clinical trial procedures is not sufficient. And while replacing legacy CTMS with cloud-based solutions seems to be the logical option, this also means implementing a major workflow overhaul, which requires retraining, identifying new roles, creating a new framework of procedures, and more. Furthermore, there is the issue with interoperability of different systems. According to a study that looks into the challenges of  clinical operations, the biggest challenge is integrating clinical applications, which is one of  legacy CTMS’ limitations. So, where would the best clinical trial management software lead you? Perhaps, in the direction of resolving these challenges.

biggest challenges of clinical applications

List of Best Clinical Trial Management Software in 2022

1. encapsia: The Holistic and Future-proof EDC

encapsia dashboard

First on our list of CTMS is encapsia. This agile software solution is designed to support decentralized clinical trials by allowing sites and organizations to create their own hybrid protocols based on study, organizational, and regulatory requirements. Another functionality that makes encapsia a powerful clinical trial management platform is its ability to capture clinical and metadata online and offline regardless of the type of data collection process.

All data is also synced to the system in real-time, which not only eliminates delays in reviewing patient information and home visit updates, it also makes relevant data readily available to other members regardless of their location. As for integration capabilities, encapsia’s REST API allows you to connect encapsia to other applications. And despite being easy to use, encapsia provides the service of consultants dedicated to helping clients tailor the platform to their study’s or organization’s precise needs.

Key Features

  • eSource
  • Electronic Data Capture (EDC)
  • Home visit
  • Live and interactive data
  • Data management and monitoring
  • Insights
  • Medical coding
  • Third-party data upload, review, and reconciliation
  • API integration

Price

  • Encapsia’s pricing is offered by quote and only available upon consultation.

2. MainEDC™: The AI-powered eClinical Platform

MainEDC dashboard

MainEDC™ is a clinical trial platform that offers a comprehensive set of fully integrated tools, including EDC, Interactive Web Response System (IWRS), drug and supply management, and electronic Patient Reported Outcome (ePro). Powered by artificial intelligence, MainEDC™ simplifies the trials and studies conducted by clinical research organizations (CROs), Big Pharma, and biotech regardless of complexity. The platform is also equipped with blockchain technology, which ensures full and accurate audit trail of your data stored in qualified data centers.

Key Features

  • Audit and inspections QA support
  • Drag-and-drop study designer
  • Built-in eCRF design approval tool
  • Central and local laboratory data handling
  • AI-powered medical coding
  • Risk based monitoring tool
  • Mobile or web-based patient access via MainEDC™ ePRO
  • Rebranding/white labeling for mobile applications and mobile and desktop website
  • Seamless integration with wearables (smart watches, fitness tracker, etc.)
  • Advanced API
  • Built-in reports
  • Real-time interactive dashboards
  • Trial and visit structure
  • Hybrid study support
  • Source data tracking for remote monitoring

Price

  • The cost of MainEDC™’s plans vary depending on the number of users and other client-specific considerations. Pricing is only available upon request.
  • Clients who want to secure private cloud, backup, and help desk support will have to pay at least $399/month.

3. EDGE: The Program Designed for Fast and Accurate Data Sharing

EDGE dashboard

EDGE  was created in the Clinical Informatics Research Unit of the University of Southampton. The purpose of this software is to provide researchers with a unique and robust platform where they can efficiently keep track of their studies from start to finish, as well as get real-time access to research data.

As a collaboration platform, EDGE is designed to eliminate task overlaps and efforts, as well as ensure the integrity and protection of patient data. As of today, EDGE is utilized by 80% of the National Health Service in England, which covers the management of than 7 million patients and research participants.

Key Features

  • Patient management and recruitment
  • Real-time workflow process capture
  • Customizable fields
  •  Shared calendars
  • In-depth reporting capabilities
  • Patient monitoring
  • Appointment and event tracking
  • Finance recording, tracking, and reports
  • Document storage and management
  • Electronic responsibility delegation log

Price

  • EDGE’s pricing plans are only available upon request.

4. Dot Compliance: The Pre-configured QMS for Life Science Industry

Dot Compliance dashboard

Dot Compliance is a quality management system designed to ensure the documentation and compliance of pharma and biotech, CROs, and medical device manufacturers. This platform offers three types of solutions that combine QMS with clinical trial management. The first is QMS Xpress, a pre-configured and deployment-ready solution ideal for organizations that are in the process of digitizing their compliance process.

Next is Compliance Xpand, which provides growing organizations with additional compliance tools they need as they scale up. Lastly, Enterprise Xact offers more flexibility for business enterprises to configure their own compliance processes.

Key Features

  • Document management
  • Change management
  • Quality event management
  • Audit management
  • Training management
  • CAPA management
  • Deviations/Non-conformances
  • Complaint management
  • Risk management
  • Supplier quality management
  • Facility equipment management
  • Electronic batch records
  • Product lifecycle management
  • Regulatory Information Management
  • Design control
  • IT compliance

Price

  • Dot Compliance’s products’ pricing plans are only available upon request.

5. VISION: The CTMS That Pre-builds Your Study

VISION dashboard

VISION is a versatile EDC tool integrated with the core features of clinical trial management and clinical data management software. A product of global eClinical solutions and services providers, Prelude Dynamics, VISION is designed for clinical trials in both human and animal health sciences.

VISION is offered in three types of solutions. First is VISION Study Builder, which enables you to create your own EDC using the platform’s user-friendly drag-and-drop interface. Next is VISION ePRO to make it easier to collect clinical data from patients and sync their information to the EDC system. And then there is the VISION Study Startup, which offers the necessary tools to help you manage your clinical studies remotely.

Key Features

  • DIY EDC builder
  • Form libraries
  • Cross-form operations
  • Create site forms
  • Quick database lock
  • On-demand reporting
  • Auto data cleaning
  • Archive in minutes
  • Audit trail enabled
  • Media upload
  • Schedule survey forms
  • Startup tracking
  • Automated reminders
  • Site initiation
  • Site scoring system
  • Site recruitment
  • Aggregated study metrics

Price

  • VISION’s pricing plans are offered by quote and only available upon consultation.

6. Florence eBinders: The Software That Fully Digitizes Your Study Binder Workflows

Florence eBinders dashboard

Florence eBinders is a leading clinical trial workflow solution that serves as an accessible and secure platform for investigator files, logs, and participant binders. This allows you to structure your own workflows according to your study and site requirements. It also comes with built-in compliance features that automate audit trails, user permissions, version control, etc.

This software solution is ideal for sponsors, CROs, and research sites that simultaneously conduct multiple studies in multiple locations as Florence eBinders offers remote monitoring options through its global dashboard, virtual workflows and task management, and more.

Key Features

  • Online document management
  • Full compliant eSignatures
  • Remote access for sites, monitors, and auditors
  • Permission-based access control
  • Flexible and custom binder structures
  • Project management
  • Automated filing of centralized documents into eBinders
  • CTMS integration
  • EMR integration
  • Outlook email integration
  • Secure and compliant audit trails
  • Dashboard for key metrics monitoring
  • Unlimited document storage
  • Custom SOP development

Price

  • Florence eBinders’ pricing plan is available upon request.

7. Castor EDC: A DCT Platform with Native ePRO Feature

Castor EDC dashboard

A modern and user-friendly clinical trial solution, Castor EDC caters to the needs of clinical trials and studies conducted by different industries. Among these industries are pharma and biotech, contract research organizations, medical device and diagnostics, and even academic research.

Castor EDC offers a compliant platform designed to capture, collect, and integrate clinical data from different sources and vendors. It also comes with ePRO and eConsent tools to make it more convenient for research participants. And beyond its powerful EDC system, this software solution also provides DCT modules for organizations that are still navigating hybrid clinical trials, as well as for those that have already implemented decentralized research.

Key Features

  • Advanced eCRFs builder
  • Flexible user management
  • Database lock
  • Up to 2GB large file uploads
  • Audit trail
  • Disaster recovery report
  • Field-level encryption
  • Two-factor authentication
  • Automated pseudonym generation
  • 15-year data retention
  • ePRO surveys
  • Smart segmentation
  • Auto-lock completed surveys
  • Real-time and automatic data save
  • Granular audit logging
  • Dynamic custom dashboard

Price

  • Castor EDC offers personalized pricing based on type of organization, type of solution, and number of patients you plan to enroll.

8. RealTime CTMS: The CTMS That Automatically Manages CRC Activities

RealTime CTMS dashboard

RealTime CTMS offers a complete clinical trial management system to help you manage research sites and networks, sponsor data, and CROs. It comes with robust scheduling tools that automate study targets and alerts and notifications on upcoming and tasks that are past due. RealTime CTMS also simplifies patient tracking with its user-friendly data entry, patient enrollment, and patient data access. Furthermore, this software solution provides advanced reporting capabilities that cover both study metrics and staff productivity.

In terms of integration, RealTime CTMS integrates with this-party platforms including Devana Solutions, Mailchimp, Twilio, Facebook ads, Outlook, and SubjectWell.

Key Features

  • Website and Facebook ads integration
  • Mobile app referral options
  • Patient referral metrics
  • Financial tracking
  • Configurable progressive recruitment statuses
  • Individual, departmental, and company calendars
  • Automated reminders
  • Email blast and mass texting campaigns
  • Task management
  • Patient visit tracking
  • Advanced reporting
  • Contracts and budgets
  • Accounting
  • Financial reports
  • Multiple integrations

Price

  • RealTime CTMS’ pricing is offered by quote.

9. Clinical Conductor: The Purpose-built CTMS for Enterprise Institutions

Clinical Conductor dashboard

A comprehensive and scalable clinical management trial management system, Clinical Conductor aims to help you streamline enrollment and communication, standardize clinical research compliance, enhance transparency and visibility, and maximize financial investments. Aside from its main CTMS platform, Clinical Conductor also offers OnCore, which is a purpose-built CTMS for enterprise institutions, such as academic medical and cancer research centers.

When it comes to integration, Clinical Conductor connects with other EDC, EMR, and other third-party systems via API.

Key Features

  • Electronic consent
  • eSource
  • eRegulatory Management System
  • Research ROI reporting
  • EDC
  • Automated participant payments
  • Dedicated platform for sponsors, sites, and participants
  • Document sharing

Price

  • Clinical Conductor’s pricing is available upon request.

10. ClinCapture: The CTMS Solution with Proprietary Clinical Cloud for Researchers

ClinCapture dashboard

ClinCapture offers a selection of proprietary EDC and VDC products for sponsors, CROs, clinical trial study consultants, and others. Its Virtual Data Capture solution contains four modules designed to support decentralized clinical trials. These modules include ePRO, eConsent, eCOA, and eSource.

Captivate Electronic Data Capture, on the other hand, provides a more advanced and scalable platform for research sites and organizations that conduct studies with varying levels of budget and complexity. Captivate EDC is also modular and can be tailored according to the needs and requirements of the study, site, or organization. Furthermore, Captivate EDC seamlessly integrates with CTMS, learning management systems, and other external integrations via web service APIs.

Key Features

  • ePRO
  • eConsent
  • eCOA
  • eSource
  • Randomization and trial supply management
  • Medical coding
  • Risk-based monitoring
  • Form versioning
  • Standard and advanced reporting and analytics
  • Advanced integrations

Price

  • Pricing plans for VDC, Captivate EDC, and individual modules are provided upon request.

11. IBM Clinical Development: The Unified CDMS with Modular EDC

IBM Clinical Development dashboard

IBM Clinical Development is a unified CDMS with powerful EDC core features to help CROs and pharmaceutical and medical device companies with their clinical trials from start to finish. Powered by IBM’s infrastructure, IBM Clinical Development offers a scalable platform that can support thousands of clinical trials. This solution is also highly adaptable and designed with an intuitive interface to make it easier for the users to navigate even complex processes.

As for its integration capabilities, IBM Clinical Development provides its users with tools to build and automate their own data connectors with minimal coding to integrate the platform with third-party systems.

Key Features

  • eCOA
  • Medical coding with Watson AI
  • Randomization and trial supply management
  • Endpoint adjudication
  • eConsent
  • Reporting and analytics
  • Data integration

Price

  • IBM Clinical Development software is offered in two pricing plans. The first is a subscription package, which includes all the core modules. The other option is pay-per-use, which gives organizations more flexibility when it comes to a module they need and how long they want to use it.

12. Dacima Clinical Suite: The Software That Combines CTMS, CDMS, and EDC

Dacima Clinical Suite dashboard

Dacima Clinical Suite is a sophisticated clinical trial application that combines CDMS, CTMS, and EDC in one platform. Aside from being an all-in-one clinical trial solution, Dacima Clinical Suite also offers flexibility as it allows users to design their own databases. All parameters are also user-configurable, which is also easy to do with its user-friendly graphical user interface that does not require any advanced programming knowledge to navigate.

Dacima Clinical Suite’s technology is built on the Microsoft.net framework and divided into three modules—administrator, designer, and data entry— each equipped with role-based capabilities and permissions. As for integrations, Dacima Clinical Suite enables you to import data from any software system, as well as with Salesforce and Rybbon Digital Gifting.

Key Features

  • Form designer
  • Dynamic visit structure
  • Subject scheduling
  • Multistage enrollment
  • Image-based data entry
  • Randomization
  • Adaptive randomization/minimization
  • Drug supply management module
  • Real-time validation checks
  • Offline data entry
  • Dynamic form activation
  • Interactive dashboards and custom reporting
  • Monitoring module
  • ePRO
  • Web survey module
  • Patient diary
  • Data importation module
  • Advanced data extraction
  • Specialized coding
  • Integrations

Price

Dacima Clinical Suite tailors its pricing plan according to the needs and requirements of clients. Clients can choose from the following offerings:

  • Academic – Web-based and ideal for clinical trial startups and academic research studies
  • Pay per study – Each module is priced individually, which makes this ideal for experimental studies.
  • Enterprise licensing – On-site software installation and includes user training. This is ideal for CROs and requires an annual support fee.

13. nQuery: The Trial Design Platform That Predicts Key Trial Milestones

nQuery dashboard

nQuery is a trial design platform for academic and commercial organizations that use Classical or Bayesian statistics, adaptive trial, and trial prediction approach to clinical studies. The platform was created to optimize and innovate clinical trial designs and speed up clinical trial procedures with the help of its robust features and utilities, such as automated sample size calculation.

nQuery’s reliability makes it a popular choice among various academic, government, and private organizations. In 2021 alone, 88% of organizations with FDA-approved clinical trials are nQuery clients. Some of them are Biogen, Sanofi, Astrazeneca, Pfizer, Johnson & Johnson, World Health Organization, the University of Miami, and more.

Key Features

  • Thousands of Fixed Term Trial Scenarios
  • Endpoints (means, survival, agreement, count, regression, etc.)
  • Designs (cross-over, stepped-wedge, cluster randomized, etc.)
  • Statement generator
  • IQ/OQ Procedures
  • Assurance
  • Credible intervals
  • Mixed Bayesian/Likelihood intervals
  • Continual reassessment method
  • Posterior error rates
  • Blinded/Unblinded Sample Size Re-estimation
  • Group Sequential Design
  • Recruitment prediction
  • Events prediction
  • Self-service knowledge base
  • 24/7 customer support

Price

nQuery has four levels of pricing plans with each price varying between academic institutions and commercial organizations.

  • Academic
    • Base – $595 per user/year
    • Plus – $895 per user//year
    • Pro – $1,645 per user/year
    • Expert – $3,495 per user/year
  • Commercial
    • Base – $695 per user/year
    • Plus – $1,045 per user/year
    • Pro – $3,295 per user/year
    • Expert – $6,995 per user/year

14. ARCS: A Research Platform That Empowers Participants

ARCS dashboard

A product of Marketing Systems Group, ARCS is designed as a panel management platform that optimizes engagement of participants. This platform is equipped with tools to help you grow your panel through its automated recruitment capabilities. Identifying the best participants for a study using ARCS’ custom screeners. This platform also eliminates the time-consuming task of scheduling research participants as they are in-charge of creating their own schedules based on their availability.

Keeping participants engaged is another area where ARCS shine as the platform implements an incentive system via products, gift cards or points ,which leaves a positive impact on participation and engagement rates. As for integrations, ARCS integrates seamlessly with social media platforms.

Key Features

  • Panel recruitment
  • Survey creation
  • Real-time survey results
  • Reporting
  • Scheduling
  • Workflow automation
  • Multi-channel engagement
  • Project management
  • Extendable data platform
  • Rewards via ARCS Pay

Price

  • ARCS’ pricing information is available upon request.

15. Clario: The CTMS That Offers Cost-effective eTMF Integration

Clario dashboard

Clario offers an end-to-end management system for clinical trials in different therapeutic areas, such as cardiac safety, infectious diseases, hepatology, neuroscience, respiratory, and oncology, among others.

Its dedicated CTMS software provides organizations with a full-featured platform that is also integrated with Electronic Trial Master File (eTMF) for more efficient, accurate, and secure consolidation of clinical data. Clario’s CTMS also utilizes the Microsoft Office work environment, which enables the platform to utilize Microsoft Office tools.

Key Features

  • eTMF integration
  • Monitoring Visit Report module
  • Microsoft Office-Smart
  • Automated workflows
  • Contact management
  • Payment module
  • Inventory control module
  • Reporting and tracking with customer-defined milestones
  • Role-based access and views
  • Extensive standard and custom reports

Price

  • Clario’s CTMS’ pricing is pay as you go and will be determined upon consultation.

16. CTMS Master: The CTMS with Fully Integrated Monitoring Tools

CTMS Master dashboard

CTMS Master is designed for optimum efficiency while keeping compliance risk at a bare minimum. One of its core capabilities is its protocol deviation management, which keeps you alert on manual and system-generated deviations. This feature also comes with automated resolution capabilities and documentation of corrective actions and improvements in the process to prevent potential issues. CTMS Master is also equipped with robust finance management tools that help streamline the budgeting, payment, and approval process.

As for integration, CTMS Master works seamlessly with other Anju Software systems, such as TrialMaster and third-party eTMF, EDC, and IVRS solutions.

Key Features

  • Custom templates
  • Integrated Site Visit Report (SVR) Tools
  • Informed consent tracking
  • Protocol deviation management
  • Study finance and budget management
  • Multiple integrations

Price

  • CTMS Master’s pricing details are available upon request.

17. OpenClinica: The EDC Platform with Customizable eCRFs

OpenClinica dashboard

OpenClinica brings smart clinical data management to clinical trials and studies. Its main offering is a powerful cloud-based EDC that can accommodate a broad spectrum of clinical research and trials, all types of therapeutic areas, as well as COVID-19 research studies

Aside from  EDC, OpenClinical also offers other solutions, such as ePRO, randomization, and reporting that can be added to the EDC system to further enhance its capabilities. OpenClinica also has its own EHR eSource integration, which enables its EDC to collect medical data from other platforms.

Key Features

  • Intuitive eCRFs
  • Drag-and-drop form builder
  • Fully integrated ePRO
  • Real-time enrollment tracking
  • Adverse events alert
  • Interactive data visualizations
  • Custom dashboards
  • Protocol compliance
  • Custom and pre-created reports
  • Patient randomization
  • EHR integration

Price

  • OpenClinica software solutions’ pricing information are available upon request.

18. Research Manager: The CTMS for Digitizing Study Requests and Portfolio Monitoring

Research Manager dashboard

Research Manager’s CTMS is designed to cater to all types of organizations within the life science sector. This platform enables organizations to fully digitize the process of study request and monitoring portfolios relevant to the study. Among the tools it offers are custom workflows, financial management, electronic document and records management, and more.

This CTMS can also integrate with Research Manager’s EDC and ethical review management system. Third-party applications can also get linked to the CTMS platform via API, SSO, SURFcontext, and EPD.

Key Features

  • Workflow management
  • Communication management
  • Role-based access control
  • Contract and document management
  • ERMS tool
  • Study dashboards
  • Financial management
  • Amendments and reports
  • Audit trail
  • Anonymized patient details
  • Smart safety reporting
  • Native and API integrations
  • Training

Price

  • Research Manager CTMS subscription plan is offered by quote and starts at €89/month.

19. Medrio: The eClinical Software for Traditional and Decentralized Clinical Trials

Medrio dashboard

Medrio offers a suite of flexible clinical trial technology for all types of industries that conduct traditional, virtual, or hybrid clinical trials. Among the solutions Medrio offers are EDC, ePRO, electronic consent, direct data capture (DDC), RTSM, and decentralized clinical trial capabilities.

Aside from software solutions, Medrio also offers services that connect clients with experts who will help them successfully carry out various clinical trial processes. These professional services include data management plan development, biostatistics, study closeout and database delivery, eCRF design and build, and more.

Key Features

  • Decentralized clinical trials
  • Direct data capture
  • Electronic data capture
  • Electronic consent
  • Randomization and trial supply management
  • Electronic patient-reported outcomes
  • Professional services

Price:

  • Medrio’s pricing information is available upon request and consultation.

20. Ripple: The CTMS with Robust Team Management Capabilities

Ripple dashboard

Ripple is a clinical trial software designed to address the biggest challenges of researchers when it comes to patient recruitment, engagement, and retention. With Ripple, all communication and information-sharing among research team members are centralized. Email alerts are also sent on a regular basis to keep each team member updated on the status of their participants.

Ripple also provides research teams with task and workflow automation tools, so the research team members can have more time to focus on their participants. Furthermore, patient journeys can be mapped out and tailored based on patient requirements, which helps enhance their experience.

Key Features

  • Custom screening forms
  • Participant profile card
  • Participant scheduling
  • Emailing and text messaging
  • Task management
  • Study dashboard
  • Custom workflows
  • Registry
  • Security and compliance

Price

  • Pricing plans for Ripple products are available upon request.

What is in store for the future of clinical trials?

There is no denying that technology plays a crucial role in modernizing clinical trial processes. And in this case, the best clinical trial management softwares serve as a fundamental element in helping research sites and organizations catch up with the modern demands of clinical studies. With clinical research becoming more and more global, cloud-based CTMS’ capability to support extensive and complicated clinical trial operations through the implementation of job automations, which have become more crucial to the speed, efficiency, accuracy, security, and ROI of modern clinical trials.

One thing that this list of leading CTMS solutions showcases is not every CTMS is a one size fits all solution. Each one, however, brings innovation in design, feature, or integration that addresses specific problems faced by research sites and organizations that are still navigating the continuously changing environment of clinical trials and research.

The need for accurate and timely digital systems spills over to governments and businesses alike. This nowhere more apparent in the need for crucial emergency management software tools to deal with all sorts of public and business emergency situations.

 

References:
  1. Agrawal, G., Moss, R., Raschke, R., Wurzer, S., & Xue, J. (2021, June 10). No place like home? Stepping up the decentralization of clinical trials. McKinsey & Company. Retrieved June 17, 2022.
  2. Babaian, D. (2021, March 29). Defining decentralized clinical trials and understanding their nuances. Advarra. Retrieved June 18, 2022.
  3. Burrows, A. (2020, January 16). REPORT: The 8 biggest challenges facing clinical trial professionals. Informa Connect. Retrieved June 19, 2022.
  4. Burrows, A. (2021, July 5). REPORT: Impacts of decentralized clinical trials 2021. Informa Connect. Retrieved June 19, 2022.
  5. ClinicalTrials.gov. (2022, June). Trends, charts, and maps. ClinicalTrials.gov. Retrieved June 17, 2022.
  6. Dagalur, S. (2016, March 18). CTMS: What you should know. Applied Clinical Trials Online. Retrieved June 17, 2022.
  7. DeBonis, D. (2020, July 24). How digital technology and remote assessment strategies can aid clinical trial research. Applied Clinical Trials Online. Retrieved June 17, 2022.
  8. ITHS. (2021, June 4). What is a clinical trial management system? CTMS Program Office. Retrieved June 17, 2022.
  9. Krofah, E., Galson, S. K., Califf, R. M., & Simon, G. (2021, August 25). Clinical trials in crisis: Building on COVID-19’s lessons toward a better future. Health Affairs: Leading Publication Of Health Policy Research & Insight. Retrieved June 17, 2022.
  10. Lasch, F., Psarelli, E., Herold, R., Mattsson, A., Guizzaro, L., Pétavy, F., & Schiel, A. (2022). The impact of COVID‐19 on the initiation of clinical trials in Europe and the United States. Clinical Pharmacology & Therapeutics, 111(5), 1093-1102. https://doi.org/10.1002/cpt.2534
  11. McKinsey & Company. (2021, January 15). Helping US healthcare stakeholders understand the human side of the COVID-19 crisis: McKinsey consumer healthcare insights. McKinsey & Company. Retrieved June 18, 2022.
  12. Parke, J. (2022, March 25). Role of current CTMS data systems and risk based monitoring as drives in a trial’s success. LinkedIn. Retrieved June 17, 2022.
  13. Parkins, K. (2022, February 4). 2022 forecast: Decentralised trials to reach new heights with 28% Jump. Clinical Trials Arena. Retrieved June 17, 2022.
  14. Veeva. (2020). Veeva 2020 unified clinical operations survey report. Veeva.com. Retrieved June 19, 2022.
  15. Wieczerzak, M. (2021, January 4). Electronic clinical trial management systems: The basics, needs, and outputs. SOCRA.org. Retrieved June 19, 2022.
  16. World Health Organization. (2022, February). Number of clinical trials by year, location, disease, phase, age and sex of trial participants. World Health Organization. Retrieved June 17, 2022.

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