World's Best Scientists 2026 revealed!
Toxicology and Applied Pharmacology
H-index 29

Toxicology and Applied Pharmacology

Ranking & Metrics

Discipline name Position Best Scientists Publications D-Index
Chemistry 519 45 45 15
Medicine 1069 66 98 22

Additional Metrics

Number of Best Scientists*: 306
Documents by Best Scientists*: 337
Top 100 Ranked Scientists*: 5
SCIMAGO H-index: 195
SCIMAGO SJR: 0.91
Impact Factor: 3.4

Overview

Top Research Topics at Toxicology and Applied Pharmacology?

The journal primarily tackles Internal medicine, Endocrinology, Biochemistry, Toxicity and Pharmacology. Toxicology and Applied Pharmacology features Internal medicine research that overlaps with concepts in Fetus. While Endocrinology is the focus of it, it also provided insights into the studies of Receptor and Gestation.

Toxicology and Applied Pharmacology holds forums on Biochemistry that merges themes from other disciplines such as Molecular biology and In vivo. The journal addresses concerns in the field of Molecular biology by exploring it in line with topics in Apoptosis which intersect with Cell biology subjects. The work on In vivo addressed in it expands to the thematically related In vitro.

The study of Pathology and how it intertwines with concepts under Lung were explored in the presented Toxicity research. The journal focuses on Pharmacology as well as the interrelated topic of Anesthesia. It connects research in Oxidative stress with the related topic of Reactive oxygen species.

  • Internal medicine (35.98%)
  • Endocrinology (35.12%)
  • Biochemistry (23.15%)

What are the most cited papers published in the journal?

  • Current status of cadmium as an environmental health problem. (1525 citations)
  • Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense (1118 citations)
  • Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. (961 citations)

Research areas of the most cited articles at Toxicology and Applied Pharmacology:

The journal publications mainly deal with areas of study such as Internal medicine, Endocrinology, Biochemistry, Toxicity and Pharmacology. The journal publications hold forums on Internal medicine that merge themes from other disciplines such as Teratology and Fetus. While Toxicity is the key highlight in the published articles, thet also covered some subjects on In vivo and In vitro.

What topics the last edition of the journal is best known for?

  • Internal medicine
  • Enzyme
  • Gene

The previous edition focused in particular on these issues:

Toxicology and Applied Pharmacology is mainly concerned with subjects like Pharmacology, Apoptosis, Internal medicine, Cancer research and Endocrinology. In the journal, Oxidative stress, In vitro, Inflammation, Toxicity and In vivo are investigated in conjunction with one another to address concerns in Pharmacology research. Toxicology and Applied Pharmacology primarily discusses Inflammation topics, particularly Proinflammatory cytokine and Inflammasome.

Toxicology and Applied Pharmacology explores topics in Apoptosis which can be helpful for research in disciplines like Reactive oxygen species, Cell biology and Cytotoxicity. The concepts on Cancer research presented in the journal can also apply to other research fields, including Carcinogenesis, Cancer, Downregulation and upregulation, Cytotoxic T cell and Lung cancer. The main emphasis of it is the research on Cancer, emphasizing the topic of Cancer cell.

The most cited articles from the last journal are:

  • Cadmium induced inflammation and apoptosis of porcine epididymis via activating RAF1/MEK/ERK and NF-κB pathways. (7 citations)
  • Edible plant-derived exosomal microRNAs: Exploiting a cross-kingdom regulatory mechanism for targeting SARS-CoV-2. (7 citations)
  • Health disparities: Intracellular consequences of social determinants of health. (6 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

The top authors publishing in Toxicology and Applied Pharmacology (based on the number of publications) are:

  • Curtis D. Klaassen (139 papers) absent at the last edition,
  • Melvin E. Andersen (80 papers) published 1 paper at the last edition, 1 less than at the previous edition,
  • Richard E. Peterson (58 papers) absent at the last edition,
  • Michael P. Waalkes (50 papers) absent at the last edition,
  • Linda S. Birnbaum (49 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Only papers with recognized affiliations are considered

The top affiliations publishing in Toxicology and Applied Pharmacology (based on the number of publications) are:

  • National Institutes of Health (535 papers) published 8 papers at the last edition, 4 more than at the previous edition,
  • Research Triangle Park (517 papers) published 7 papers at the last edition, 4 more than at the previous edition,
  • United States Environmental Protection Agency (258 papers) published 4 papers at the last edition the same number as at the previous edition,
  • University of Kansas (248 papers) published 1 paper at the last edition, 5 less than at the previous edition,
  • Michigan State University (245 papers) published 1 paper at the last edition, 1 less than at the previous edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 4.80% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 8.40% were posted by at least one author from the top 10 institutions publishing in the journal. Another 2.94% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 7.14% of all publications and 81.51% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

  • Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
  • Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
  • Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
  • Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
  • Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Top Publications

  • Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways

    (2020)
    75 Citations
  • Effects of physicochemical properties of TiO2 nanomaterials for pulmonary inflammation, acute phase response and alveolar proteinosis in intratracheally exposed mice.

    Pernille Høgh Danielsen;Kristina Bram Knudsen;Janez Štrancar;Polona Umek

    (2020)
    74 Citations
  • Exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate during adulthood disrupts hormones and ovarian folliculogenesis throughout the prime reproductive life of the mouse

    Catheryne Chiang;Lily R. Lewis;Grace Borkowski;Jodi A. Flaws

    (2020)
    63 Citations
  • The role of STAT3/p53 and PI3K-Akt-mTOR signaling pathway on DEHP-induced reproductive toxicity in pubertal male rat

    (2020)
    53 Citations
  • The effects of a phthalate metabolite mixture on antral follicle growth and sex steroid synthesis in mice.

    Daryl D. Meling;Genoa R. Warner;Jason R. Szumski;Liying Gao

    (2020)
    52 Citations
  • The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice.

    (2022)
    51 Citations
  • 4-methylpyrazole protects against acetaminophen-induced acute kidney injury.

    Jephte Y. Akakpo;Anup Ramachandran;Hilmi Orhan;Steven C. Curry

    (2020)
    48 Citations
  • Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth.

    Madeleine Böckers;Norbert W. Paul;Thomas Efferth

    (2020)
    42 Citations
  • Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPARα mice fed an American diet.

    J.J. Schlezinger;T. Hyötyläinen;T. Sinioja;C. Boston

    (2021)
    40 Citations
  • Induction of apoptosis in breast cancer cells by naphthylisoquinoline alkaloids.

    Prem Prakash Kushwaha;Atul Kumar Singh;Kumari Sunita Prajapati;Mohd Shuaib

    (2020)
    40 Citations

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Best Scientists Contributing to This Journal