Clinical Science (Portland Press)

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Top Publications

• Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities.

  Cody C Gifford;Jiaqi Tang;Angelica Costello;Nidah S Khakoo

  (2021)
  124 Citations

• The role of adipose tissue senescence in obesity- and ageing-related metabolic disorders.

  Zhuohao Liu;Kelvin Ka-Lok Wu;Xue Jiang;Xue Jiang;Aimin Xu

  (2020)
  103 Citations

• Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis.

  Sandra Rayego-Mateos;Sofia Campillo;Raúl R Rodrigues-Diez;Raúl R Rodrigues-Diez;Antonio Tejera-Muñoz

  (2021)
  96 Citations

• Cardiotoxic effects of angiogenesis inhibitors

  Stephen J.H. Dobbin;Mark C. Petrie;Rachel C. Myles;Rhian M. Touyz

  (2021)
  89 Citations

• Inflammation: a putative link between phosphate metabolism and cardiovascular disease.

  Jakob Voelkl;Jakob Voelkl;Daniela Egli-Spichtig;Ioana Alesutan;Carsten A. Wagner

  (2021)
  82 Citations

• ACE2 and gut amino acid transport.

  Simone M R Camargo;Raphael N Vuille-Dit-Bille;Raphael N Vuille-Dit-Bille;Chantal F Meier;François Verrey

  (2020)
  79 Citations

• ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19.

  Rhian M. Touyz;Hongliang Li;Christian Delles

  (2020)
  74 Citations

• Aetiology of Type 2 diabetes in people with a ‘normal’ body mass index: testing the personal fat threshold hypothesis

  (2023)
  67 Citations

• ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease.

  Jithin Kuriakose;Augusto C. Montezano;Rhian M. Touyz

  (2021)
  67 Citations

• Klotho and calciprotein particles as therapeutic targets against accelerated ageing.

  Makoto Kuro-o

  (2021)
  66 Citations

• Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice.

  Kana N Miyata;Chao-Sheng Lo;Shuiling Zhao;Min-Chun Liao

  (2021)
  65 Citations

• New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis

  (2023)
  64 Citations

• Lipotoxicity: a driver of heart failure with preserved ejection fraction?

  Jennifer Leggat;Guillaume Bidault;Antonio Vidal-Puig

  (2021)
  59 Citations

• Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function.

  Zhuo Li;Zhuo Li;Hua Guo;Hua Guo;Jia Li;Jia Li;Tianjiao Ma;Tianjiao Ma

  (2020)
  57 Citations

• Neuregulins: protective and reparative growth factors in multiple forms of cardiovascular disease.

  Andrew Geissler;Sergey Ryzhov;Douglas B. Sawyer

  (2020)
  51 Citations

• Targeting perivascular and epicardial adipose tissue inflammation: therapeutic opportunities for cardiovascular disease.

  Rim Rafeh;Anissa Viveiros;Gavin Y Oudit;Ahmed F El-Yazbi;Ahmed F El-Yazbi

  (2020)
  47 Citations

• ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19.

  Koichi Yamamoto;Hikari Takeshita;Hiromi Rakugi

  (2020)
  47 Citations