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Thomas W. Mühleisen

Thomas W. Mühleisen

D-Index & Metrics

Genetics

D-Index
68
Citations
45277
World Ranking
2381
National Ranking
38

Overview

Thomas W. Mühleisen is affiliated with the University of Basel in Switzerland. Their research spans multiple fields with a primary focus on biochemistry, genetics, and molecular biology, complemented by work in medicine. The scientist has published extensively in various subfields, including genetics, molecular biology, cardiology and cardiovascular medicine, cognitive neuroscience, and developmental and educational psychology.

The main topics of research covered by Mühleisen include genetic associations and epidemiology, epigenetics and DNA methylation, genomic variations and chromosomal abnormalities, congenital heart defects research, genetics and neurodevelopmental disorders, heart rate variability and autonomic control, as well as cardiac electrophysiology and arrhythmias.

Mühleisen's recent publications highlight their involvement in brain structure genetics, psychiatric illness, and cognitive alterations linked to genetic variations. Selected recent works include:

  • "Genetic variants associated with longitudinal changes in brain structure across the lifespan," 2022, published in Nature Neuroscience
  • "Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs," 2021, Human Brain Mapping
  • "1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans," 2021, Translational Psychiatry
  • "A common variation in HCN1 is associated with heart rate variability in schizophrenia," 2020, Schizophrenia Research
  • "Identification of Phonology-Related Genes and Functional Characterization of Broca's and Wernicke's Regions in Language and Learning Disorders," 2021, Frontiers in Neuroscience

The venues where Mühleisen frequently publishes reflect the thematic focus of the research, including Translational Psychiatry, bioRxiv (Cold Spring Harbor Laboratory), NeuroImage, Nature Neuroscience, and Human Brain Mapping.

Collaborations with other researchers play a significant role in Mühleisen's work. Frequent co-authors include Sven Cichon, Andreas J. Forstner, Robin Bülow, Christiane Jockwitz, and Katrin Amunts, with each contributing to multiple publications together.

Overall, Thomas W. Mühleisen's scholarly output centers around the genetic and molecular bases of brain structure, psychiatric and neurodevelopmental disorders, and cardiovascular genetics, integrating epidemiological genetics with molecular and clinical approaches.

Best Publications

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

    D Harold;R Abraham;P Hollingworth;R Sims

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

    Heribert Schunkert;Inke R. König;Sekar Kathiresan;Muredach P. Reilly

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Large recurrent microdeletions associated with schizophrenia

    Hreinn Stefansson;Dan Rujescu;Sven Cichon;Olli P. H. Pietilainen

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Genetic associations with valvular calcification and aortic stenosis.

    George Thanassoulis;George Thanassoulis;Catherine Y. Campbell;David S. Owens;J. Gustav Smith;J. Gustav Smith

  • Common genetic variants influence human subcortical brain structures.

    Derrek P. Hibar;Jason L. Stein;Jason L. Stein;Miguel E. Renteria;Alejandro Arias-Vasquez

  • Aging of blood can be tracked by DNA methylation changes at just three CpG sites.

    Carola Ingrid Weidner;Qiong Lin;Carmen Maike Koch;Lewin Eisele

  • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

    Lesley Jones;Peter A. Holmans;Marian L. Hamshere;Denise Harold

  • The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

    Paul M. Thompson;Jason L. Stein;Sarah E. Medland;Derrek P. Hibar

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I Berndt;Stefan Gustafsson;Stefan Gustafsson;Reedik Mägi;Reedik Mägi;Andrea Ganna

  • An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Robert A. Scott;Laura J. Scott;Reedik Mägi;Letizia Marullo

  • Identification of common variants associated with human hippocampal and intracranial volumes

    Jason L Stein;Sarah E Medland;Sarah E Medland;Alejandro Arias Vasquez;Alejandro Arias Vasquez;Derrek P Hibar

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

Frequent Co-Authors

Markus M. Nöthen
Markus M. Nöthen University Hospital Bonn
Sven Cichon
Sven Cichon University of Basel
Marcella Rietschel
Marcella Rietschel Heidelberg University
Manuel Mattheisen
Manuel Mattheisen Dalhousie University
Thomas G. Schulze
Thomas G. Schulze Ludwig-Maximilians-Universität München
Jana Strohmaier
Jana Strohmaier Heidelberg University
Stefan Herms
Stefan Herms University of Basel
Susanne Moebus
Susanne Moebus University of Duisburg-Essen
Stephanie H. Witt
Stephanie H. Witt Heidelberg University
Roel A. Ophoff
Roel A. Ophoff University of California, Los Angeles

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