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Chemistry

D-Index
40
Citations
10383
World Ranking
17830
National Ranking
4349

Overview

Takeru Higuchi was affiliated with the University of Wisconsin-Madison in the United States. Their research spanned several fields, most notably Materials Science and Biochemistry, Genetics and Molecular Biology. Their work contributed significantly to the subfields of Materials Chemistry, Molecular Biology, Organic Chemistry, Biomaterials, and Physiology.

The scientist's research topics included:

  • Porphyrin and Phthalocyanine Chemistry
  • Supramolecular Self-Assembly in Materials
  • Polyamine Metabolism and Applications
  • Luminescence and Fluorescent Materials
  • Supramolecular Chemistry and Complexes
  • DNA and Nucleic Acid Chemistry
  • Spaceflight effects on biology

Among their recent papers were the following:

  • "Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity" (2021), published in Journal of Medicinal Chemistry
  • "Effects of Structural Isomers of Spermine on the Higher-Order Structure of DNA and Gene Expression" (2021), published in International Journal of Molecular Sciences
  • "Clustering of charged colloidal particles in the microgravity environment of space" (2023), published in npj Microgravity
  • "Fluorescence Response and Self-Assembly of a Tweezer-Type Synthetic Receptor Triggered by Complexation with Heme and Its Catabolites" (2020), published in Chemistry - A European Journal
  • "Control of the stepwise self-assembly process of a pH-responsive amphiphilic 4-aminoquinoline-tetraphenylethene conjugate" (2023), published in Nanoscale

Frequent co-authors included:

  • Naoki Umezawa
  • Yosuke Hisamatsu
  • Hiroshi Takase
  • Katsuhiro Yamamoto
  • Hiroyuki Miki

The scientist regularly published in a range of venues such as:

  • Chemistry - A European Journal
  • npj Microgravity
  • Journal of Medicinal Chemistry
  • International Journal of Molecular Sciences
  • Nanoscale

Best Publications

  • Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices

    T. Higuchi

  • Rate of release of medicaments from ointment bases containing drugs in suspension

    Takeru Higuchi

  • Dissolution Behavior of Crystalline Solvated and Nonsolvated Forms of Some Pharmaceuticals

    Eli Shefter;Takeru Higuchi

  • Naphthalene-2,3-dicarboxyaldehyde/cyanide ion: a rationally designed fluorogenic reagent for primary amines

    Pierre. De Montigny;John F. Stobaugh;Richard S. Givens;Robert G. Carlson

  • Solubility behavior of organic compounds

    David J. W. Grant;Takeru Higuchi

  • Polymorphism and drug availability. Solubility relationships in the methylprednisolone system

    W.I. Higuchi;P.K. Lau;T. Higuchi;J.W. Shell

  • Theoretical analysis of diffusional movement through heterogeneous barriers

    W.I. Higuchi;Takeru Higuchi

  • N-substituted 1-cyanobenz[f]isoindole: evaluation of fluorescence efficiencies of a new fluorogenic label for primary amines and amino acids.

    Bogdan K. Matuszewski;Richard S. Givens;Kasturi. Srinivasachar;Robert G. Carlson

  • Rates of hydrolysis of carbamate and carbonate esters in alkaline solution

    Lewis W. Dittert;Lewis W. Dittert;Takeru Higuchi

  • Multiple intermediates generate fluorophore-derived light in the oxalate/peroxide chemiluminescence system

    Francisco J. Alvarez;Nikhil J. Parekh;Bogdan. Matuszewski;Richard S. Givens

  • Thermodynamic group contributions from ion pair extraction equilibriums for use in the prediction of partition coefficients. Correlation of surface area with group contributions

    Sister Marie Joan Harris;Takeru Higuchi;J. Howard Rytting

  • Quantitative analytical method for determination of drugs dispersed in polymers using differential scanning calorimetry.

    Felix Theeuwes;Anwar Hussain;Takeru Higuchi

  • IMPROVED DELIVERY THROUGH BIOLOGICAL MEMBRANES. 4. PRODRUGS OF L-DOPA

    N. Bodor;K. B. Sloan;T. Higuchi;K. Sasahara

  • Improved delivery through biological membranes. 4. Prodrugs of L-dopa.

    Nicholas Bodor;Kenneth B. Sloan;Takeru Higuchi;Kunihiro Sasahara

  • PHASE SOLUBILITY TECHNIQUE IN STUDYING THE FORMATION OF COMPLEX SALTS OF TRIAMTERENE.

    Lewis W. Dittert;Lewis W. Dittert;Takeru Higuchi;Takeru Higuchi;Davis R. Reese;Davis R. Reese

  • The Physics of Tablet Compression. II. The Influence of Degree of Compression on Properties of Table

    T. Higuchi;A. Narsimha Rao;J.W. Busse;J.V. Swintosky

  • MICELLAR ACCELERATION OF ORGANOPHOSPHATE HYDROLYSIS BY HYDROXIMINOMETHYLPYRIDINIUM TYPE SURFACTANTS

    J. Epstein;J. J. Kaminski;N. Bodor;R. Enever

  • Ion pair extraction of pharmaceutical amines. Role of dipolar solvating agents in extraction of dextromethorphan.

    Takeru. Higuchi;Arthur F. Michaelis;T. Tan;Arthur R. Hurwitz

  • The Physics of Tablet Compression: V. Studies on Aspirin, Lactose, Lactose-Aspirin, and Sulfadiazine Tablets

    T. Higuchi;L.N. Elowe;L.W. Busse

  • Plastic electrodes specific for organic ions

    Takeru. Higuchi;C. R. Illian;J. L. Tossounian

  • Investigation of Drug Release from Solids II.*: Theoretical and Experimental Study of Influences of Bases and Buffers on Rates of Dissolution of Acidic Solids

    W.I. Higuchi;Eugene L. Parrott;Dale E. Wurster;T. Higuchi

  • Investigation of some complexes formed in solution by caffeine. IV. Interactions between caffeine and sulfathiazole, sulfadiazine, p-aminobenzoic acid, benzocaine, phenobarbital, and barbital.

    Takeru Higuchi;John L. Lach

  • Improved delivery through biological membranes. 1. Synthesis and properties of 1-methyl-1,6-dihydropyridine-2-carbaldoxime, a pro-drug of N-methylpyridinium-2-carbaldoxime chloride

    Nicolae Bodor;Efraim Shek;Takeru Higuchi

  • Calculation of stability constants of hydrogen-bonded complexes from proton magnetic resonance data. Interactions of phenol with dimethylacetamide and various ketones. Solvent effect

    Masahiro Nakano;Naomi I. Nakano;Takeru Higuchi

  • Improved delivery through biological membranes. 3. Delivery of N-methylpyridinium-2-carbaldoxime chloride through the blood-brain barrier in its dihydropyridine pro-drug form.

    Efraim Shek;Takeru Higuchi;Nicolae Bodor

  • N-Halo Derivatives V: Comparative Antimicrobial Activity of Soft N-Chloramine Systems

    James J. Kaminski;M. Maureen Huycke;Sally H. Selk;Nicolae Bodor

  • Reversible association of caffeine and of some caffeine homologs in aqueous solution.

    David Guttman;Takeru Higuchi

Frequent Co-Authors

Nicholas Bodor
Nicholas Bodor University of Florida
William I. Higuchi
William I. Higuchi University of Utah
Richard L. Schowen
Richard L. Schowen University of Kansas

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