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Takashi Deguchi

Takashi Deguchi

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
11268
World Ranking
10994
National Ranking
753

Overview

Takashi Deguchi is affiliated with Gifu University in Japan and has contributed extensively to research in medicine and related disciplines. Their work spans a variety of specialized fields including surgery, pulmonary and respiratory medicine, molecular biology, infectious diseases, and microbiology.

Deguchi's main research topics include bladder and urothelial cancer treatments, urinary and genital oncology studies, reproductive tract infections research, bacterial infections and vaccines, syphilis diagnosis and treatment, Enterobacteriaceae and Cronobacter research, and bacterial identification and susceptibility testing.

Frequent venues for Deguchi's publications include Cureus, with six publications, Cancer Genomics & Proteomics and bioRxiv (Cold Spring Harbor Laboratory), each with two publications, as well as Genome Medicine and CEN Case Reports.

Their recent papers feature a range of topics, such as antimicrobial resistance, kidney disease, COVID-19 impacts on healthcare workers, and diagnostic methodologies:

  • Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae, 2021, Genome Medicine
  • Subclinical acute tubular necrosis potentially associated with red yeast rice consumption unexpectedly detected in a patient with membranous nephropathy, 2024, CEN Case Reports
  • Evaluation of physical and psychological status of health care workers infected with COVID-19 during a hospital outbreak in Japan, 2022, Journal of Infection and Chemotherapy
  • The performance of a Fully Automated Urine Particle Analyzer, Sysmex UF-5000, in detecting fastidious bacteria in urine samples, 2024, Journal of Microbiological Methods
  • Current antihypertensive treatment and treatment-resistant hypertension in Japanese patients with chronic kidney disease, 2022, Clinical and Experimental Nephrology

Deguchi frequently collaborates with several researchers, including Koji Kameyama (6 joint publications), Mitsuru Yasuda (5), Shigeaki Yokoi (5), Shingo Kamei (5), and Tetsuya Yamada (5).

Their contributions to multiple areas of medicine and biochemistry exemplify interdisciplinary approaches addressing clinical and molecular challenges in infectious diseases and oncology.

Best Publications

  • Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells.

    Yasunori Fujita;Keitaro Kojima;Nanako Hamada;Riyako Ohhashi

  • Emergence and Spread of Neisseria gonorrhoeae Clinical Isolates Harboring Mosaic-Like Structure of Penicillin-Binding Protein 2 in Central Japan

    Masayasu Ito;Takashi Deguchi;Koh-Suke Mizutani;Mitsuru Yasuda

  • MiR‐34a attenuates paclitaxel‐resistance of hormone‐refractory prostate cancer PC3 cells through direct and indirect mechanisms

    Keitaro Kojima;Yasunori Fujita;Yoshinori Nozawa;Yoshinori Nozawa;Takashi Deguchi

  • Association of Ureaplasma urealyticum (biovar 2) with nongonococcal urethritis.

    Takashi Deguchi;Takashi Yoshida;Takamaro Miyazawa;Mitsuru Yasuda

  • MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression

    Yasunori Fujita;Keitaro Kojima;Keitaro Kojima;Riyako Ohhashi;Nanako Hamada

  • Threat to Cefixime Treatment for Gonorrhea

    Shigeaki Yokoi;Takashi Deguchi;Tomomi Ozawa;Mitsuru Yasuda

  • A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells.

    Keitaro Kojima;Riyako Ohhashi;Yasunori Fujita;Nanako Hamada

  • Chemopreventive effects of diosmin and hesperidin on N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine‐induced urinary‐bladder carcinogenesis in male ICR mice

    Muzheng Yang;Takuji Tanaka;Yoshinobu Hirose;Takashi Deguchi

  • Detection of Micrometastatic Prostate Cancer Cells in Lymph Nodes by Reverse Transcriptase-Polymerase Chain Reaction

    Takashi Deguchi;Tatsuo Doi;Hideo Ehara;Shin-ichi Ito

  • Quinolone-resistant Neisseria gonorrhoeae: correlation of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV with antimicrobial susceptibility profiles.

    T Deguchi;M Yasuda;M Nakano;S Ozeki

  • Comparison of two alpha1-adrenoceptor antagonists, naftopidil and tamsulosin hydrochloride, in the treatment of lower urinary tract symptoms with benign prostatic hyperplasia: a randomized crossover study.

    Yoshinori Nishino;Takako Masue;Kousei Miwa;Yoshito Takahashi

  • Increased activity and intranuclear expression of phospholipase D2 in human renal cancer.

    Yutong Zhao;Hidetoshi Ehara;Yukihiro Akao;Masayo Shamoto

  • Quantitative Detection of Mycoplasma genitalium from First-Pass Urine of Men with Urethritis and Asymptomatic Men by Real-Time PCR

    Takashi Yoshida;Takashi Deguchi;Masayasu Ito;Shin-Ichi Maeda

  • Emergence of clinical strains of Mycoplasma genitalium harbouring alterations in ParC associated with fluoroquinolone resistance.

    Yasushi Shimada;Takashi Deguchi;Keita Nakane;Takako Masue

  • Phylogeny-Based Rapid Identification of Mycoplasmas and Ureaplasmas from Urethritis Patients

    Takashi Yoshida;Shin-Ichi Maeda;Takashi Deguchi;Hiroaki Ishiko

  • Rapid Detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum Organisms in Genitourinary Samples by PCR-Microtiter Plate Hybridization Assay

    Takashi Yoshida;Shin Ichi Maeda;Takashi Deguchi;Takamaro Miyazawa

  • Cisplatin induces production of reactive oxygen species via NADPH oxidase activation in human prostate cancer cells.

    Tomohiro Itoh;Riyako Terazawa;Keitaro Kojima;Keita Nakane

  • Alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in quinolone-resistant clinical isolates of Klebsiella pneumoniae.

    T Deguchi;A Fukuoka;M Yasuda;M Nakano

  • Remarkable increase in central Japan in 2001-2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones.

    Masayasu Ito;Mitsuru Yasuda;Shigeaki Yokoi;Shin-ichi Ito

  • Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval.

    Takashi Deguchi;Mitsuru Yasuda;Shigeaki Yokoi;Ken-Ichiro Ishida

Frequent Co-Authors

Takayuki Ezaki
Takayuki Ezaki Gifu University
Hiroaki Ishiko
Hiroaki Ishiko Mitsubishi Chemical (Japan)
Seiji Naito
Seiji Naito Kyushu University
Shiro Shigeta
Shiro Shigeta Fukushima Medical University
Shigeru Kohno
Shigeru Kohno Nagasaki University
Hiroyuki Yamamoto
Hiroyuki Yamamoto St. Marianna University School of Medicine
Masayuki Nakagawa
Masayuki Nakagawa Kagoshima University
Yoshiaki Kawamura
Yoshiaki Kawamura Aichi Gakuin University
Makoto Ohnishi
Makoto Ohnishi National Institutes of Health
Naoki Yamamoto
Naoki Yamamoto National University of Singapore

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