Michelle L. Block

Best Publications

• Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

  Michelle L. Block;Luigi Zecca;Jau Shyong Hong

  4779
  Citations

• Systemic LPS Causes Chronic Neuroinflammation and Progressive Neurodegeneration

  Liya Qin;Xuefei Wu;Michelle L. Block;Yuxin Liu;Yuxin Liu

  2499
  Citations

• Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism

  Michelle L. Block;Jau Shyong Hong

  1892
  Citations

• Aggregated α-synuclein activates microglia: a process leading to disease progression in Parkinson’s disease

  Wei Zhang;Tongguang Wang;Zhong Pei;David S. Miller

  1527
  Citations

• Microglial activation and chronic neurodegeneration

  Melinda E. Lull;Michelle L. Block

  1206
  Citations

• NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

  Liya Qin;Yuxin Liu;Tongguang Wang;Sung Jen Wei

  688
  Citations

• Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase

  M. L. Block;X. Wu;X. Wu;Z. Pei;G. Li

  437
  Citations

• Chronic microglial activation and progressive dopaminergic neurotoxicity

  M.L. Block;M.L. Block;J.-S. Hong

  420
  Citations

• Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

  Xuefei Wu;Po See Chen;Po See Chen;Shannon Dallas;Belinda Wilson

  363
  Citations

• Neuroinflammation, Hyperphosphorylated Tau, Diffuse Amyloid Plaques, and Down-Regulation of the Cellular Prion Protein in Air Pollution Exposed Children and Young Adults

  Lilian Calderón-Garcidueas;Michael Kavanaugh;Michelle Block;Amedeo D'Angiulli

  305
  Citations

• Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model

  Yun Ding;Aimin Qiao;Ziqing Wang;J. Shawn Goodwin

  302
  Citations

• Interactive role of the toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation.

  Liya Qin;Guorong Li;Xun Qian;Yuxin Liu

  248
  Citations

• A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation

  Yoon Seong Kim;Dong Hee Choi;Michelle L. Block;Stefan Lorenzl

  239
  Citations

• NADPH oxidase as a therapeutic target in Alzheimer's disease

  Michelle L Block

  227
  Citations

• Outdoor Ambient Air Pollution and Neurodegenerative Diseases: the Neuroinflammation Hypothesis

  Richard L. Jayaraj;Eric A. Rodriguez;Yi Wang;Michelle L. Block

  207
  Citations

• The role of microglia in paraquat-induced dopaminergic neurotoxicity.

  Xue Fei Wu;Michelle L. Block;Wei Zhang;Liya Qin;Liya Qin

  200
  Citations

• Microglial priming through the lung–brain axis: the role of air pollution–induced circulating factors

  Christen L. Mumaw;Shannon Levesque;Constance McGraw;Sarah Robertson

  185
  Citations

• Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors.

  Michael J. Surace;Michelle L. Block

  165
  Citations

• Reactive microgliosis: extracellular μ-calpain and microglia-mediated dopaminergic neurotoxicity

  Shannon Levesque;Belinda Wilson;Vincent Gregoria;Laura B. Thorpe

  149
  Citations

• Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage

  Guorong Li;Gang Cui;Nian Ssheng Tzeng;Sung Jen Wei

  144
  Citations