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Biology and Biochemistry

D-Index
64
Citations
25266
World Ranking
9442
National Ranking
719

Overview

Michael R. Barnes is affiliated with Queen Mary University of London in the United Kingdom. Their research spans several interconnected fields, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology.

Their work has contributed significantly to subfields including Molecular Biology, Immunology, Artificial Intelligence, Genetics, and Rheumatology. The scientist's research topics reflect diverse interests such as Psoriasis: Treatment and Pathogenesis, Gene expression and cancer classification, Rheumatoid Arthritis Research and Therapies, Bioinformatics and Genomic Networks, Dermatology and Skin Diseases, Computational Drug Discovery Methods, and Cell Image Analysis Techniques.

Michael R. Barnes has authored numerous papers, some of the notable recent publications include:

  • Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial, 2022, Nature Medicine
  • Reaching the End-Game for GWAS: Machine Learning Approaches for the Prioritization of Complex Disease Loci, 2020, Frontiers in Genetics
  • M3C: Monte Carlo reference-based consensus clustering, 2020, Scientific Reports
  • The benefits and pitfalls of machine learning for biomarker discovery, 2023, Cell and Tissue Research
  • Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction, 2020, Nature Communications

The scientist frequently collaborates with scholars such as Nick J. Reynolds, Juliet N. Barker, Catherine Smith, Richard B. Warren, and Myles Lewis. This network of coauthors reflects ongoing partnerships in their research endeavors.

Michael R. Barnes' publications appear regularly in a range of venues, including:

  • arXiv (Cornell University)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • British Journal of Dermatology
  • UNC Libraries
  • Nature Communications

The diversity of publication outlets highlights engagement with both preprint repositories and peer-reviewed journals specializing in genetics, dermatology, and broader medical research.

Best Publications

  • Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity

    L K Hosking;P R Boyd;C F Xu;M Nissum

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

    Brett E. Johnson;Tali Mazor;Chibo Hong;Michael Barnes

  • A mega-analysis of genome-wide association studies for major depressive disorder

    Stephan Ripke;Naomi R Wray;Cathryn M Lewis;Steven P Hamilton

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

  • Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

    Hao Li;Sally Wetten;Li Li;Pamela L. St. Jean

  • Disruption of the neurexin 1 gene is associated with schizophrenia

    Dan Rujescu;Andres Ingason;Andres Ingason;Sven Cichon;Olli P.H. Pietiläinen

  • Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

    Sergio E. Baranzini;Nicholas W. Galwey;Joanne Wang;Pouya Khankhanian

  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Georg B. Ehret;Georg B. Ehret;Teresa Ferreira;Daniel I. Chasman;Anne U. Jackson

  • Use of genome-wide association studies for drug repositioning.

    Philippe Sanseau;Pankaj Agarwal;Michael R Barnes;Michael R Barnes;Tomi Pastinen

  • Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

    Rudolf Uher;Nader Ali Perroud;Mandy Y. M. Ng;Joanna Hauser

  • Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

    Myles J. Lewis;Michael R. Barnes;Michael R. Barnes;Kevin Blighe;Katriona Goldmann

  • Health and population effects of rare gene knockouts in adult humans with related parents.

    Vagheesh M. Narasimhan;Karen A. Hunt;Dan Mason;Christopher L. Baker

  • Experimental comparison and cross-validation of the Affymetrix and Illumina gene expression analysis platforms

    Michael Barnes;Johannes Freudenberg;Susan Thompson;Bruce Aronow

  • Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

    Iris Postmus;Stella Trompet;Harshal A. Deshmukh;Michael R. Barnes

  • Genome-wide association study of major recurrent depression in the U.K. population

    Cathryn M. Lewis;Mandy Y. Ng;Amy W. Butler;Sarah Cohen-Woods

  • Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

    Hector R. Wong;Thomas P. Shanley;Bhuvaneswari Sakthivel;Natalie Cvijanovich

  • A mega-analysis of genome-wide association studies for major depressive disorder

    S. Ripke;N. R. Wray;C. M. Lewis;S. P. Hamilton

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Patricia B. Munroe
Patricia B. Munroe Queen Mary University of London
Andrew P. Morris
Andrew P. Morris University of Liverpool
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Christopher Newton-Cheh
Christopher Newton-Cheh Harvard University
Mark J. Caulfield
Mark J. Caulfield Queen Mary University of London
Bruce M. Psaty
Bruce M. Psaty University of Washington
Tonu Esko
Tonu Esko University of Tartu
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
Erik Ingelsson
Erik Ingelsson Stanford University
Daniel I. Chasman
Daniel I. Chasman Brigham and Women's Hospital

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