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Neuroscience

D-Index
39
Citations
5926
World Ranking
8340
National Ranking
138

Overview

Manuel Alegre is affiliated with the University of Navarra in Spain. Their research focuses broadly on Medicine and Neuroscience, with particular interests in Cognitive Neuroscience, Molecular Biology, Neurology, Physiology, and Pulmonary and Respiratory Medicine.

Their work covers several main topics including:

  • Porphyrin Metabolism and Disorders
  • Heme Oxygenase-1 and Carbon Monoxide
  • Obstructive Sleep Apnea Research
  • Neonatal Health and Biochemistry
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Neuroscience and Neural Engineering

Several recent papers authored or coauthored by Manuel Alegre illustrate their research scope:

  • "mRNA-based therapy in a rabbit model of variegate porphyria offers new insights into the pathogenesis of acute attacks" (2021, Molecular Therapy - Nucleic Acids)
  • "Recombinant porphobilinogen deaminase targeted to the liver corrects enzymopenia in a mouse model of acute intermittent porphyria" (2022, Science Translational Medicine)
  • "Brain oscillations and Parkinson disease" (2022, Handbook of clinical neurology)
  • "Effects of dexmedetomidine on subthalamic local field potentials in Parkinson's disease" (2021, British Journal of Anaesthesia)
  • "Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates" (2024, Gut)

The frequent co-authors in Alegre's collaborations indicate ongoing research partnerships with:

  • Daniel Jericó
  • Karol M. Córdoba
  • Ana Sampedro
  • Antonio Fontanellas
  • Oscar Manzanilla

Alegre's publications are often featured in the following venues:

  • British Journal of Anaesthesia
  • Molecular Therapy - Nucleic Acids
  • Gut
  • Science Translational Medicine
  • Handbook of clinical neurology

Best Publications

  • Coupling between Beta and High-Frequency Activity in the Human Subthalamic Nucleus May Be a Pathophysiological Mechanism in Parkinson's Disease

    Jon López-Azcárate;Mikel Tainta;María C. Rodríguez-Oroz;Miguel Valencia

  • Slow oscillatory activity and levodopa-induced dyskinesias in Parkinson's disease.

    F Alonso-Frech;I Zamarbide;M Alegre;M C Rodríguez-Oroz

  • Independent component analysis as a tool to eliminate artifacts in EEG: a quantitative study.

    Jorge Iriarte;Elena Urrestarazu;Miguel Valencia;Manuel Alegre

  • Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinson's disease.

    Maria C. Rodriguez-Oroz;Maria C. Rodriguez-Oroz;Jon López-Azcárate;David Garcia-Garcia;Manuel Alegre;Manuel Alegre

  • Movement-related changes in oscillatory activity in the human subthalamic nucleus: ipsilateral vs. contralateral movements.

    M. Alegre;F. Alonso-Frech;M. C. Rodríguez-Oroz;J. Guridi

  • Parkinson's disease, the subthalamic nucleus, inhibition, and impulsivity.

    Marjan Jahanshahi;Ignacio Obeso;Christelle Baunez;Manuel Alegre

  • Beta electroencephalograph changes during passive movements: sensory afferences contribute to beta event-related desynchronization in humans.

    M. Alegre;A. Labarga;A. Labarga;I.G. Gurtubay;J. Iriarte

  • The subthalamic nucleus is involved in successful inhibition in the stop-signal task: a local field potential study in Parkinson's disease.

    Manuel Alegre;Jon Lopez-Azcarate;Ignacio Obeso;Leonora Wilkinson

  • Systemic messenger RNA as an etiological treatment for acute intermittent porphyria.

    Lei Jiang;Pedro Berraondo;Pedro Berraondo;Daniel Jericó;Lin T Guey

  • Independent Component Analysis Removing Artifacts in Ictal Recordings

    Elena Urrestarazu;Jorge Iriarte;Manuel Alegre;Miguel Valencia

  • High beta activity in the subthalamic nucleus and freezing of gait in Parkinson's disease.

    Jon B. Toledo;Jon López-Azcárate;David Garcia-Garcia;Jorge Guridi

  • Frontal and central oscillatory changes related to different aspects of the motor process: a study in go/no-go paradigms.

    M. Alegre;I. G. Gurtubay;A. Labarga;J. Iriarte

  • Changes in subthalamic activity during movement observation in Parkinson’s disease: Is the mirror system mirrored in the basal ganglia?

    M. Alegre;M.C. Rodríguez-Oroz;M. Valencia;M. Pérez-Alcázar

  • Alpha and beta oscillatory changes during stimulus-induced movement paradigms: effect of stimulus predictability.

    Manuel Alegre;Inaki G. Gurtubay;Alberto Labarga;Jorge Iriarte

  • Movement-related changes in cortical oscillatory activity in ballistic, sustained and negative movements.

    Alegre M;Labarga A;Gurtubay Ig;Iriarte J

  • Memantine induces reversible neurologic impairment in patients with MS

    P. Villoslada;G. Arrondo;J. Sepulcre;M. Alegre

  • Changes in the heart rate variability in patients with obstructive sleep apnea and its response to acute CPAP treatment.

    Ernesto Kufoy;Jose-Alberto Palma;Jon Lopez;Manuel Alegre

  • Gamma band activity in an auditory oddball paradigm studied with the wavelet transform

    I.G Gurtubay;M Alegre;A Labarga;A Malanda

  • Potentials evoked by chirp-modulated tones: a new technique to evaluate oscillatory activity in the auditory pathway.

    J Artieda;M Valencia;M Alegre;O Olaziregi

  • Successful thalamic deep brain stimulation for orthostatic tremor

    Jorge Guridi;Maria C. Rodriguez-Oroz;Javier Arbizu;Manuel Alegre

Frequent Co-Authors

Julio Artieda
Julio Artieda University of Navarra
Jon B. Toledo
Jon B. Toledo Houston Methodist
Marjan Jahanshahi
Marjan Jahanshahi University College London
Jorge Sepulcre
Jorge Sepulcre Harvard University
José L. Lanciego
José L. Lanciego University of Navarra
Christelle Baunez
Christelle Baunez Aix-Marseille University
Paul Krack
Paul Krack University of Bern
Joshua S. Shimony
Joshua S. Shimony Washington University in St. Louis
Romain Carron
Romain Carron Hôpital de la Timone
Keyoumars Ashkan
Keyoumars Ashkan King's College London

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