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Manabu Tokeshi

Manabu Tokeshi

D-Index & Metrics

Chemistry

D-Index
64
Citations
14599
World Ranking
8047
National Ranking
539

Overview

Manabu Tokeshi is affiliated with Hokkaido University in Japan. Their research primarily bridges the fields of Biochemistry, Genetics and Molecular Biology, and Engineering, with a notable focus on Molecular Biology and Biomedical Engineering. Their work also contributes to Immunology, Infectious Diseases, and Electrical and Electronic Engineering.

The main topics of Tokeshi's research cover various aspects of biosensing, gene delivery, and microfluidic techniques. These include:

  • Biosensors and Analytical Detection
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Microfluidic and Capillary Electrophoresis Applications
  • Advanced Biosensing Techniques and Applications
  • Immunotherapy and Immune Responses
  • Innovative Microfluidic and Catalytic Techniques Innovation

Tokeshi has published extensively in scientific journals, with frequent appearances in the following venues:

  • Journal of Controlled Release
  • Sensors and Actuators B Chemical
  • ACS Omega
  • ACS Applied Materials & Interfaces
  • Biosensors and Bioelectronics

Selected recent publications highlight topics primarily related to lipid nanoparticles, microfluidics, and RNA delivery systems:

  • Microfluidic technologies and devices for lipid nanoparticle-based RNA delivery, 2022, Journal of Controlled Release
  • Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol), 2020, Nature Communications
  • The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution, 2020, Molecular Pharmaceutics
  • Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery, 2020, ACS Applied Materials & Interfaces
  • Lipid nanoparticles loaded with ribonucleoprotein-oligonucleotide complexes synthesized using a microfluidic device exhibit robust genome editing and hepatitis B virus inhibition, 2020, Journal of Controlled Release

Frequent co-authors collaborating with Tokeshi include:

  • Masatoshi Maeki
  • Akihiko Ishida
  • Hirofumi Tani
  • Hideyoshi Harashima
  • Yusuke Sato

Best Publications

  • Integration of an immunosorbent assay system: analysis of secretory human immunoglobulin A on polystyrene beads in a microchip.

    Kiichi Sato;Manabu Tokeshi;Tamao Odake;Hiroko Kimura

  • Determination of carcinoembryonic antigen in human sera by integrated bead-bed immunoasay in a microchip for cancer diagnosis

    Kiichi Sato;Manabu Tokeshi;Hiroko Kimura;Takehiko Kitamori

  • Continuous-flow chemical processing on a microchip by combining microunit operations and a multiphase flow network.

    Manabu Tokeshi;Tomoko Minagawa;Kenji Uchiyama;Akihide Hibara

  • Integration of a microextraction system on a glass chip: ion-pair solvent extraction of Fe(II) with 4,7-diphenyl-1,10-phenanthrolinedisulfonic acid and tri-n-octylmethylammonium chloride

    Manabu Tokeshi;Tomoko Minagawa;Takehiko Kitamori

  • Trafficking and subcellular localization of multiwalled carbon nanotubes in plant cells.

    Maged F. Serag;Noritada Kaji;Claire Gaillard;Yukihiro Okamoto

  • Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems.

    Masatoshi Maeki;Niko Kimura;Yusuke Sato;Hideyoshi Harashima

  • Nanochannels on a Fused-Silica Microchip and Liquid Properties Investigation by Time-Resolved Fluorescence Measurements

    Akihide Hibara;Takumi Saito;Haeng Boo Kim;Manabu Tokeshi

  • Determination of Subyoctomole Amounts of Nonfluorescent Molecules Using a Thermal Lens Microscope: Subsingle-Molecule Determination

    Manabu Tokeshi;Marika Uchida;Akihide Hibara;Tsuguo Sawada

  • Microchip-based immunoassay system with branching multichannels for simultaneous determination of interferon-γ

    Kiichi Sato;Maho Yamanaka;Hiroko Takahashi;Manabu Tokeshi

  • Peer Reviewed: Thermal Lens Microscopy and Microchip Chemistry

    Takehita Kitamori;Manabu Tokeshi;Akihide Hibara;Kiichi Sato

  • Microchip-based chemical and biochemical analysis systems

    Kiichi Sato;Akihide Hibara;Manabu Tokeshi;Hideaki Hisamoto

  • Fast and high conversion phase-transfer synthesis exploiting the liquid–liquid interface formed in a microchannel chip

    Hideaki Hisamoto;Takumi Saito;Manabu Tokeshi;Akihide Hibara

  • Integrated multilayer flow system on a microchip.

    Akihide Hibara;Manabu Tokeshi;Kenji Uchiyama;Hideaki Hisamoto

  • Advances in Microfluidic Paper-Based Analytical Devices for Food and Water Analysis.

    Lori Shayne Alamo Busa;Saeed Mohammadi;Masatoshi Maeki;Akihiko Ishida

  • Single-Cell Analysis by a Scanning Thermal Lens Microscope with a Microchip: Direct Monitoring of Cytochrome c Distribution during Apoptosis Process

    Eiichiro Tamaki;Kiichi Sato;Manabu Tokeshi;Kae Sato

  • Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol).

    Yubo Wang;Jose Enrico Q. Quinsaat;Tomoko Ono;Masatoshi Maeki

  • Chemicofunctional Membrane for Integrated Chemical Processes on a Microchip

    Hideaki Hisamoto;Yuki Shimizu;Kenji Uchiyama;Manabu Tokeshi

  • Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo

    Yusuke Sato;Kazuki Hashiba;Kosuke Sasaki;Masatoshi Maeki

  • Surface modification method of microchannels for gas-liquid two-phase flow in microchips.

    Akihide Hibara;Shinobu Iwayama;Shinya Matsuoka;Masaharu Ueno

  • Stabilization of Liquid Interface and Control of Two-Phase Confluence and Separation in Glass Microchips by Utilizing Octadecylsilane Modification of Microchannels

    Akihide Hibara;Masaki Nonaka;Hideaki Hisamoto;Kenji Uchiyama

  • Glass microchip with three-dimensional microchannel network for 2 × 2 parallel synthesis

    Yoshikuni Kikutani;Takayuki Horiuchi;Kenji Uchiyama;Hideaki Hisamoto

  • Thermal lens microscope

    Takehiko Kitamori;Akihide Hibara;Manabu Tokeshi

Frequent Co-Authors

Yoshinobu Baba
Yoshinobu Baba Nagoya University
Takehiko Kitamori
Takehiko Kitamori University of Tokyo
Hideyoshi Harashima
Hideyoshi Harashima Hokkaido University
Yasuo Shinohara
Yasuo Shinohara University of Tokushima
Kazuma Mawatari
Kazuma Mawatari Waseda University
Takeshi Yanagida
Takeshi Yanagida University of Tokyo
Tomoji Kawai
Tomoji Kawai Osaka University
Kentaro Kogure
Kentaro Kogure University of Tokushima
Yoshinori Hasegawa
Yoshinori Hasegawa Nagoya University
Mats Nilsson
Mats Nilsson Swedish University of Agricultural Sciences

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