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D-Index
57
Citations
13724
World Ranking
4308
National Ranking
1951

Overview

Lique M. Coolen is affiliated with Kent State University in the United States and specializes in the field of Medicine, with a particular focus on Reproductive Medicine. Their research extensively covers the hypothalamic control of reproductive hormones and ovarian function and disorders.

Their work also spans several subfields including Molecular Biology, Social Psychology, Cellular and Molecular Neuroscience, and Endocrine and Autonomic Systems.

Coolen has contributed to multiple research topics, such as:

  • Hypothalamic control of reproductive hormones
  • Ovarian function and disorders
  • Plant Reproductive Biology
  • Neuroendocrine regulation and behavior
  • Neuropeptides and Animal Physiology
  • Regulation of Appetite and Obesity
  • Eicosanoids and Hypertension Pharmacology

Their most frequent publication venues include:

  • Endocrinology
  • Journal of Neuroendocrinology
  • Frontiers in Neurology
  • Proceedings of the National Academy of Sciences
  • Frontiers in Endocrinology

Notable recent papers authored by Coolen are:

  • Prenatal Androgen Exposure Alters KNDy Neurons and Their Afferent Network in a Model of Polycystic Ovarian Syndrome, 2021, Endocrinology
  • In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse, 2022, Proceedings of the National Academy of Sciences
  • 20-HETE Enzymes and Receptors in the Neurovascular Unit: Implications in Cerebrovascular Disease, 2020, Frontiers in Neurology
  • Highlights of neuroanatomical discoveries of the mammalian gonadotropin-releasing hormone system, 2022, Journal of Neuroendocrinology
  • Lesions of KNDy and Kiss1R Neurons in the Arcuate Nucleus Produce Different Effects on LH Pulse Patterns in Female Sheep, 2023, Endocrinology

Frequent collaborative partners in research include:

  • Michael N. Lehman
  • Robert L. Goodman
  • Aleisha M. Moore
  • Stanley M. Hileman
  • Kayla M. Onslow

Lique M. Coolen's work addresses complex questions related to neuroendocrine regulation, particularly involving hypothalamic neurons and their roles in reproductive processes. Their publications often investigate mechanisms underlying hormone pulse generation and related neuronal networks.

Best Publications

  • Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion.

    Michael N. Lehman;Lique M. Coolen;Robert L. Goodman

  • Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.

    Robert L Goodman;Michael N Lehman;Jeremy Troy Smith;Lique M Coolen

  • The Catabolic Action of Insulin in the Brain Is Mediated by Melanocortins

    Stephen C. Benoit;Ellen L. Air;Lique M. Coolen;Richelle Strauss

  • Identification of a potential ejaculation generator in the spinal cord.

    William A. Truitt;Lique M. Coolen

  • A Role for Neurokinin B in Pulsatile GnRH Secretion in the Ewe

    Robert L. Goodman;Lique M. Coolen;Michael N. Lehman

  • Variation in Kisspeptin and RFamide-Related Peptide (RFRP) Expression and Terminal Connections to Gonadotropin-Releasing Hormone Neurons in the Brain: A Novel Medium for Seasonal Breeding in the Sheep

    Jeremy T. Smith;Lique M. Coolen;Lance J. Kriegsfeld;Ika P. Sari

  • Fos immunoreactivity in the rat brain following consummatory elements of sexual behavior: a sex comparison

    Lique M Coolen;Hans J.P.W Peters;Jan G Veening

  • The Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cell Population of the Arcuate Nucleus: Sex Differences and Effects of Prenatal Testosterone in Sheep

    Guanliang Cheng;Lique M. Coolen;Vasantha Padmanabhan;Robert L. Goodman

  • Evidence that dynorphin plays a major role in mediating progesterone negative feedback on gonadotropin-releasing hormone neurons in sheep.

    Robert L. Goodman;Lique M. Coolen;Greg M. Anderson;Steven L. Hardy

  • Central regulation of ejaculation

    Lique M. Coolen;Julien Allard;William A. Truitt;William A. Truitt;Kevin E. McKenna

  • Bidirectional connections of the medial amygdaloid nucleus in the Syrian hamster brain: simultaneous anterograde and retrograde tract tracing.

    Lique M. Coolen;Ruth I. Wood

  • Neurokinin 3 Receptor Immunoreactivity in the Septal Region, Preoptic Area and Hypothalamus of the Female Sheep: Colocalisation in Neurokinin B Cells of the Arcuate Nucleus but not in Gonadotrophin‐Releasing Hormone Neurones

    M. Amstalden;L. M. Coolen;L. M. Coolen;A. M. Hemmerle;Heather J. Billings;Heather J. Billings

  • Kisspeptin, neurokinin B, and dynorphin act in the arcuate nucleus to control activity of the GnRH pulse generator in ewes.

    Robert L. Goodman;Stanley M. Hileman;Casey C Nestor;Katrina L. Porter

  • Neural activation following sexual behavior in the male and female rat brain.

    Jan G Veening;Lique M Coolen

  • Sexual behavior and sex-associated environmental cues activate the mesolimbic system in male rats.

    Margaret E Balfour;Lei Yu;Lique M Coolen

  • Anatomy of the kisspeptin neural network in mammals.

    Michael N. Lehman;Christina M. Merkley;Lique M. Coolen;Robert L. Goodman

  • KNDy Cells Revisited.

    Aleisha M Moore;Lique M Coolen;Danielle T Porter;Robert L Goodman

  • Molecular mapping of the neural pathways linking leptin to the neuroendocrine reproductive axis

    Gwendolyn W. Louis;Megan Greenwald-Yarnell;Rebecca Phillips;Lique M. Coolen

  • Distribution of Fos immunoreactivity following mating versus anogenital investigation in the male rat brain.

    L.M Coolen;H.J.P.W Peters;J.G Veening

  • KNDy (Kisspeptin/Neurokinin B/Dynorphin) Neurons Are Activated during Both Pulsatile and Surge Secretion of LH in the Ewe

    Christina M. Merkley;Katrina L. Porter;Lique M. Coolen;Stanley M. Hileman

  • Do similar neural systems subserve aggressive and sexual behaviour in male rats? Insights from c-Fos and pharmacological studies.

    Jan G. Veening;Lique M. Coolen;Trynke R. de Jong;Henk W. Joosten

Frequent Co-Authors

Jan G. Veening
Jan G. Veening Radboud University
Neil M. Richtand
Neil M. Richtand University of California - San Diego School of Medicine
Steven R. Laviolette
Steven R. Laviolette University of Western Ontario
Michael T. Shipley
Michael T. Shipley University of Maryland, Baltimore
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Yu-Qiu Zhang
Yu-Qiu Zhang Fudan University
James P. Herman
James P. Herman University of Cincinnati
Vincent Vialou
Vincent Vialou Sorbonne University
Stephen C. Benoit
Stephen C. Benoit University of Cincinnati
Maureen A. Sartor
Maureen A. Sartor University of Michigan–Ann Arbor

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