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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
46282
World Ranking
11072
National Ranking
851

Overview

Laura Clarke is affiliated with the European Bioinformatics Institute in the United Kingdom. Their research spans multiple interconnected fields with a strong focus on medicine, particularly molecular biology and pathology.

The primary fields of study in Clarke's body of work include Medicine, with specific focus areas such as Molecular Biology, Pathology and Forensic Medicine, Polymers and Plastics, Neurology, and Electrical and Electronic Engineering. The scientist's work integrates aspects of these fields to explore both biological and material science topics.

The main research topics covered by Clarke reflect a diverse scientific portfolio, including:

  • Conducting polymers and applications
  • Multiple Sclerosis Research Studies
  • Single-cell and spatial transcriptomics
  • Peripheral Neuropathies and Disorders
  • Fuel Cells and Related Materials
  • Molecular Biology Techniques and Applications
  • Ocular Diseases and Behçet's Syndrome

Clarke has contributed to various scientific publications, including papers in the following venues where they have published frequently:

  • Journal of Polymer Science
  • Nature Communications
  • Nature Cell Biology
  • Frontiers in Neurology
  • Journal of Neurology

Recent notable papers include:

  • Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression (2020), published in Nature Communications
  • Expression Atlas update: gene and protein expression in multiple species (2021), published in Nucleic Acids Research
  • The Organoid Cell Atlas (2020), published in Nature Biotechnology
  • Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP) (2023), published in Nature Cell Biology
  • Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease (2021), published in Nature Communications

In their collaborative work, Clarke frequently coauthors with the following researchers:

  • Tae-Lim Choi
  • Craig J. Hawker
  • Herman Mark
  • Takuzo Aida
  • Pinar Akcora

Best Publications

  • A global reference for human genetic variation.

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • Genome sequence of the Brown Norway rat yields insights into mammalian evolution

    Richard A. Gibbs;George M. Weinstock;Michael L. Metzker;Donna M. Muzny

  • An integrated map of structural variation in 2,504 human genomes

    Peter H. Sudmant;Tobias Rausch;Eugene J. Gardner;Robert E. Handsaker;Robert E. Handsaker

  • Evolutionary and biomedical insights from the rhesus macaque genome

    Richard A. Gibbs;Jeffrey Rogers

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • The Ensembl gene annotation system.

    Bronwen L. Aken;Bronwen L. Aken;Sarah Ayling;Daniel Barrell;Laura Clarke

  • The genome sequence of Caenorhabditis briggsae: A platform for comparative genomics

    Lincoln D Stein;Zhirong Bao;Zhirong Bao;Darin Blasiar;Thomas Blumenthal

  • Multi-platform discovery of haplotype-resolved structural variation in human genomes

    Mark J.P. Chaisson;Mark J.P. Chaisson;Ashley D. Sanders;Xuefang Zhao;Xuefang Zhao;Ankit Malhotra

  • Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

    Valerie A. Schneider;Tina Graves-Lindsay;Kerstin Howe;Nathan Bouk

  • A global reference for human genetic variation

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • Genome analysis of the platypus reveals unique signatures of evolution

    Wesley C. Warren;La Deana W. Hillier;Jennifer A. Marshall Graves;Ewan Birney

  • Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

    Lu Chen;Lu Chen;Bing Ge;Francesco Paolo Casale;Louella Vasquez

  • Common genetic variation drives molecular heterogeneity in human iPSCs

    Helena Kilpinen;Angela Goncalves;Andreas Leha;Vackar Afzal

  • A map of human genome variation from population-scale sequencing

    Richard M. Durbin;David L. Altshuler;Gonçalo R. Abecasis;David R. Bentley

  • An Overview of Ensembl

    Ewan Birney;T. Daniel Andrews;Paul Bevan;Mario Caccamo

  • β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

    Boris Novakovic;Ehsan Habibi;Shuang-Yin Wang;Rob J.W. Arts

  • The Ensembl Automatic Gene Annotation System

    Val Curwen;Eduardo Eyras;T. Daniel Andrews;Laura Clarke

  • Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics

    Ekta Khurana;Yao Fu;Vincenza Colonna;Vincenza Colonna;Xinmeng Jasmine Mu

  • The 1000 Genomes Project: data management and community access

    Laura Clarke;Xiangqun Zheng-Bradley;Richard Smith;Eugene Kulesha

  • Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences

    G David Poznik;Yali Xue;Fernando L Mendez;Thomas F Willems

Frequent Co-Authors

Paul Flicek
Paul Flicek The Jackson Laboratory
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge
Hendrik G. Stunnenberg
Hendrik G. Stunnenberg Radboud University
Joost H.A. Martens
Joost H.A. Martens Radboud University
Richard Durbin
Richard Durbin University of Cambridge
Nicole Soranzo
Nicole Soranzo Wellcome Sanger Institute
Oliver Stegle
Oliver Stegle German Cancer Research Center
Ewan Birney
Ewan Birney European Molecular Biology Laboratory
Simon Heath
Simon Heath Pompeu Fabra University
Evan E. Eichler
Evan E. Eichler University of Washington

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