Koichi Koshimizu

Overview

Best Publications

• Inhibitory effect of citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice.

  Akira Murakami;Yoshimasa Nakamura;Koji Torikai;Takuji Tanaka

  460
  Citations

• Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the α,β-unsaturated carbonyl group is a prerequisite

  Akira Murakami;Daisuke Takahashi;Takashi Kinoshita;Koichi Koshimizu

  427
  Citations

• Inhibitory effects of ursolic and oleanolic ancid on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate

  Harukuni Tokuda;Hajime Ohigashi;Koichi Koshimizu;Yohei Ito

  365
  Citations

• Niaziminin, a Thiocarbamate from the Leaves of Moringa oleifera, Holds a Strict Structural Requirement for Inhibition of Tumor-Promoter-Induced Epstein-Barr Virus Activation

  Akira Murakami;Yumi Kitazono;Suratwadee Jiwajinda;Koichi Koshimizu

  303
  Citations

• Search for possible antitumor promoters by inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation; Ursolic acid and oleanolic acid from an anti-inflammatory Chinese medicinal plant, Glechoma hederaceae L.

  Hajime Ohigashi;Hitoshi Takamura;Koichi Koshimizu;Harukuni Tokuda

  224
  Citations

• Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes.

  Akira Murakami;Wataru Kuki;Yasuo Takahashi;Hiroshi Yonei

  222
  Citations

• Anti-tumor Promoting Activity of Bufadienolides from Kalanchoe pinnata and K. daigremontiana × butiflora

  Unang Supratman;Tomoyuki Fujita;Kohki Akiyama;Hideo Hayashi

  217
  Citations

• Anti-tumor Promotion with Food Phytochemicals: A Strategy for Cancer Chemoprevention

  Akira Murakami;Hajime Ohigashi;Koichi Koshimizu

  205
  Citations

• Bitter steroid glucosides, vernoniosides A1, A2, and A3, and related B1 from a possible medicinal plant, Vernonia amygdalina, used by wild chimpanzees.

  Mitsuo Jisaka;Hajime Ohigashi;Teruyoshi Takagaki;Hiroshi Nozaki

  190
  Citations

• Citrus Auraptene Exerts Dose-dependent Chemopreventive Activity in Rat Large Bowel Tumorigenesis: The Inhibition Correlates with Suppression of Cell Proliferation and Lipid Peroxidation and with Induction of Phase II Drug-metabolizing Enzymes

  Takuji Tanaka;Kunihiro Kawabata;Mikio Kakumoto;Akira Hara

  188
  Citations

• Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation.

  Akira Murakami;Miyuki Takahashi;Suratwadee Jiwajinda;Koichi Koshimizu

  177
  Citations

• Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-γ-induced IκB degradation in RAW264.7 macrophages

  Akira Murakami;Kazuhiko Matsumoto;Koichi Koshimizu;Hajime Ohigashi

  174
  Citations

• Glyceroglycolipids from Citrus hystrix, a Traditional Herb in Thailand, Potently Inhibit the Tumor-Promoting Activity of 12-O-Tetradecanoylphorbol 13-Acetate in Mouse Skin

  Akira Murakami;Yoshimasa Nakamura;Koichi Koshimizu;Hajime Ohigashi

  173
  Citations

• Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells

  Qiao Zheng;Yoshinobu Hirose;Naoki Yoshimi;Akira Murakami

  169
  Citations

• Suppressive effects of citrus fruits on free radical generation and nobiletin, an anti-inflammatory polymethoxyflavonoid.

  Akira Murakami;Yoshimasa Nakamura;Yoshimi Ohto;Masamichi Yano

  159
  Citations

• Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet.

  Takuji Tanaka;Masahito Shimizu;Hiroyuki Kohno;Shin-ichiro Yoshitani

  154
  Citations

• Modifying effects of carotenoids on superoxide and nitric oxide generation from stimulated leukocytes.

  Akira Murakami;Mamiko Nakashima;Teruaki Koshiba;Takashi Maoka

  151
  Citations

• Use of Vernonia amygdalina by wild chimpanzee : possible roles of its bitter and related constituents

  Koichi Koshimizu;Hajime Ohigashi;Michael A. Huffman

  149
  Citations

• Toward the chemical ecology of medicinal plant use in chimpanzees: The case ofVernonia amygdalina, a plant used by wild chimpanzees possibly for parasite-related diseases.

  Hajime Ohigashi;Michael A. Huffman;Daisuke Izutsu;Koichi Koshimizu

  145
  Citations

• Antitumoral and antimicrobial activities of bitter sesquiterpene lactones of Vernonia amygdalina, a possible medicinal plant used by wild chimpanzees.

  Mitsuo Jisaka;Hajime Ohigashi;Kazunori Takegawa;Michael A. Huffman

  143
  Citations

• FA15, a hydrophobic derivative of ferulic acid, suppresses inflammatory responses and skin tumor promotion: comparison with ferulic acid

  Akira Murakami;Yoshimasa Nakamura;Koichi Koshimizu;Daisuke Takahashi

  142
  Citations

• 1,1-Dimethylallylcoumarins potently supress both lipopolysaccharide- and interferon-γ-induced nitric oxide generation in mouse macrophage RAW 264.7 cells

  Akira Murakami;Guanxin Gao;Mitsuo Omura;Masamichi Yano

  135
  Citations

• 1'-Acetoxychavicol acetate, a superoxide anion generation inhibitor, potently inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in ICR mouse skin.

  Akira Murakami;Shin Ohura;Yoshimasa Nakamura;Koichi Koshimizu

  128
  Citations

• Screening for in vitro anti-tumor promoting activities of edible plants from Thailand

  Akira Murakami;Suratwadee Jiwajinda;Koichi Koshimizu;Hajime Ohigashi

  119
  Citations