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Biology and Biochemistry

D-Index
76
Citations
19147
World Ranking
5085
National Ranking
382

Overview

John D. Aplin is affiliated with the University of Manchester in the United Kingdom. Their research primarily focuses on medicine, with a significant concentration in obstetrics and gynecology, immunology, molecular biology, pediatrics, perinatology, child health, and reproductive medicine.

Their scientific work extensively covers topics related to pregnancy and preeclampsia, the reproductive system and pregnancy, birth, development, and health, as well as areas involving endometriosis research and treatment. Additional areas of interest include glycosylation and glycoproteins research, reproductive biology and fertility, and reproductive physiology in livestock.

John D. Aplin has published numerous articles in a variety of scientific journals. Frequent publication venues include:

  • Placenta
  • Proceedings of the National Academy of Sciences
  • Human Reproduction
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Reproduction Update

Their recent significant papers include:

  • Tracking placental development in health and disease, 2020, Nature Reviews Endocrinology
  • ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development, 2021, Proceedings of the National Academy of Sciences
  • Cell dynamics in human villous trophoblast, 2021, Human Reproduction Update
  • Trophectoderm differentiation to invasive syncytiotrophoblast is promoted by endometrial epithelial cells during human embryo implantation, 2022, Human Reproduction
  • Intersection of regulatory pathways controlling hemostasis and hemochorial placentation, 2021, Proceedings of the National Academy of Sciences

Their collaborative work frequently involves scientists such as Carolyn Jones, Peter T Ruane, Melissa Westwood, Terence Garner, and Adam Stevens.

Best Publications

  • Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.

    A Sonnenberg;J Calafat;H Janssen;H Daams

  • Evidence for immune cell involvement in decidual spiral arteriole remodeling in early human pregnancy.

    Samantha D. Smith;Caroline E. Dunk;John D. Aplin;Lynda K. Harris

  • Implantation, trophoblast differentiation and haemochorial placentation: Mechanistic evidence in vivo and in vitro

    John D. Aplin

  • Human Endometrial Mucin MUC1 Is Up-Regulated by Progesterone and Down-Regulated In Vitro by the Human Blastocyst

    M Meseguer;J D Aplin;P Caballero-Campo;J E O'Connor

  • Yoga for Chronic Low Back Pain: A Randomized Trial

    Helen E. Tilbrook;Helen Cox;Catherine E. Hewitt;Arthur Ricky Kang'ombe

  • Tumor Necrosis Factor-α Inhibits Trophoblast Migration through Elevation of Plasminogen Activator Inhibitor-1 in First-Trimester Villous Explant Cultures

    Sandra Bauer;Jürgen Pollheimer;Johannes Hartmann;Peter Husslein

  • Cell adhesion molecules on the oocyte and preimplantation human embryo

    S. Campbell;H.R. Swann;M.W. Seif;S.J. Kimber

  • Epithelial-mesenchymal transition during trophoblast differentiation.

    L. Vićovac;John D. Aplin

  • Adhesion molecules in implantation.

    John D. Aplin

  • Human placental explants in culture: approaches and assessments.

    R.K. Miller;O. Genbacev;M.A. Turner;J.D. Aplin

  • Trophoblast-uterine interactions at implantation.

    John D Aplin;Susan J Kimber

  • Tracking placental development in health and disease.

    John D. Aplin;Jenny E. Myers;Kate Timms;Melissa Westwood

  • Preparation, properties, and applications of carbohydrate conjugates of proteins and lipids.

    Aplin Jd;Wriston Jc

  • Embryo–epithelium interactions during implantation at a glance

    John D. Aplin;Peter T. Ruane

  • Insulin-like growth factor I and II regulate the life cycle of trophoblast in the developing human placenta.

    Karen Forbes;Melissa Westwood;Philip N. Baker;John D. Aplin

  • Adhesion molecules in endometrial epithelium: tissue integrity and embryo implantation.

    Harmeet Singh;John D. Aplin

  • Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure

    Madhuri S Salker;Mark Christian;Jennifer H Steel;Jaya Nautiyal

  • Trophoblast differentiation during formation of anchoring villi in a model of the early human placenta in vitro.

    L. Vićovac;C.J.P. Jones;J.D. Aplin;J.D. Aplin

  • Expression of integrin α6β4 in human trophoblast and its loss from extravillous cells

    John D. Aplin

  • Invasive trophoblasts stimulate vascular smooth muscle cell apoptosis by a fas ligand-dependent mechanism.

    Lynda K. Harris;Rosemary J. Keogh;Mark Wareing;Philip N. Baker

Frequent Co-Authors

Carolyn J.P. Jones
Carolyn J.P. Jones University of Manchester
Philip N. Baker
Philip N. Baker University of Leicester
Susan J. Kimber
Susan J. Kimber University of Manchester
Linda C. Giudice
Linda C. Giudice University of California, San Francisco
Tin-Chiu Li
Tin-Chiu Li Chinese University of Hong Kong
Ian D. Cooke
Ian D. Cooke University of Sheffield
Helen Cox
Helen Cox University of Cape Town
David J. Torgerson
David J. Torgerson University of York
Laurance D. Hall
Laurance D. Hall University of Cambridge
Terence D Allen
Terence D Allen University of Manchester

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