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Isao Shimizu

Isao Shimizu

D-Index & Metrics

Chemistry

D-Index
47
Citations
7345
World Ranking
15709
National Ranking
1236

Overview

Isao Shimizu is a researcher affiliated with Waseda University in Japan. Their work spans several fields including Neuroscience, Biochemistry, Genetics and Molecular Biology, as well as Physics and Astronomy. The research focus covers subfields such as Cellular and Molecular Neuroscience, Molecular Biology, Pharmacology, Atomic and Molecular Physics, and Optics, as well as Biophysics.

Shimizu's research topics include Axon Guidance and Neuronal Signaling, Angiogenesis and VEGF in Cancer, Neuropeptides and Animal Physiology, Treatment of Major Depression, Neurotransmitter Receptor Influence on Behavior, Neuroscience and Neuropharmacology Research, and Digital Holography and Microscopy.

The scientist has published in a variety of journals, reflecting the multidisciplinary nature of their work. Frequent publication venues include:

  • International Journal of Molecular Sciences
  • Psychopharmacology
  • The European Physical Journal Applied Physics

Recent papers authored or co-authored by Shimizu include:

  • "Analysis of ADAM12-Mediated Ephrin-A1 Cleavage and Its Biological Functions," 2021, International Journal of Molecular Sciences
  • "DSP-6745, a novel 5-hydroxytryptamine modulator with rapid antidepressant, anxiolytic, antipsychotic and procognitive effects," 2024, Psychopharmacology
  • "Contrast-tuneable microscopy for single-shot real-time imaging," 2020, The European Physical Journal Applied Physics

Shimizu has collaborated frequently with several co-authors, including:

  • Katsuaki Ieguchi
  • Takeshi Tomita
  • Toshifumi Takao
  • Tsutomu Omori
  • Taishi Mishima

The diversity in Shimizu's research output demonstrates a blend of biological and physical sciences, focusing both on molecular mechanisms relevant to neuroscience and novel technological approaches such as microscopy methods.

Best Publications

  • Allylic carbonates. Efficient allylating agents of carbonucleophiles in palladium-catalyzed reactions under neutral conditions

    Jiro Tsuji;Isao Shimizu;Ichiro Minami;Yukihiro Ohashi

  • Palladium-catalyzed rearrangement of allylic esters of acetoacetic acid to give γ,δ-unsaturated methyl ketones

    Isao Shimizu;Toshiro Yamada;Jiro Tsuji

  • Palladium-catalyzed [3 + 2] cycloaddition reaction of vinylcyclopropanes with α,β-unsaturated esters or ketones

    Isao Shimizu;Yukihiro Ohashi;Jiro Tsuji

  • Novel palladium-catalyzed reactions of propargyl carbonates with carbonucleophiles under neutral conditions

    Jiro Tsuji;Hiroyuki Watanabe;Ichiro Minami;Isao Shimizu

  • Synthesis of trifluoromethyl ketones by palladium-catalyzed cross-coupling reaction of phenyl trifluoroacetate with organoboron compounds

    Ryuki Kakino;Isao Shimizu;Akio Yamamoto

  • Facile Palladium catalyzed decarboxylative allylation of active methylene compounds under neutral conditions using allylic carbonates

    Jiro Tsuji;Isao Shimizu;Ichiro Minami;Yukihiro Ohashi

  • Palladium-catalyzed allylation of ketones and aldehydes via allyl enol carbonates

    Jiro Tsuji;Ichiro Minami;Isao Shimizu

  • Palladium-catalyzed selective hydrogenolysis of alkenyloxiranes with formic acid. Stereoselectivity and synthetic utility

    Masato Oshima;Hiroyuki Yamazaki;Isao Shimizu;Mohammad Nisar

  • Reactions of allylic carbonates catalyzed by palladium, rhodium, ruthenium, molybdenum, and nickel complexes; allylation of carbonucleophiles and decarboxylation- dehydrogenation

    Ichiro Minami;Isao Shimizu;Jiro Tsuji

  • Synthesis of Unsymmetrical Ketones by Palladium-Catalyzed Cross-Coupling Reaction of Carboxylic Anhydrides with Organoboron Compounds

    Ryuki Kakino;Sayaka Yasumi;Isao Shimizu;Akio Yamamoto

  • Activation of C–O and C–N Bonds in Allylic Alcohols and Amines by Palladium Complexes Promoted by CO2. Synthetic Applications to Allylation of Nucleophiles, Carbonylation, and Allylamine Disproportionation

    Masato Sakamoto;Isao Shimizu;Akio Yamamoto

  • Palladium-catalyzed decarboxylation-allylation of allylic esters of α-substituted β-keto carboxylic, malonic, cyanoacetic, and nitroacetic acids

    Jiro Tsuji;Toshiro Yamada;Ichiro Minami;Masami Yuhara

  • New synthetic methods for α,β -unsaturated ketones, aldehydes, esters and lactones by the palladium-catalyzed reactions of silyl enol ethers, ketene silyl acetals, and enol acetates with allyl carbonates

    Ichiro Minami;Kazuhiko Takahashi;Isao Shimizu;Tsuneo Kimura

  • Palladium-catalyzed decarboxylation-dehydrogenation of allyl .beta.-oxo carboxylates and allyl enol carbonates as a novel synthetic method for .alpha.-substituted .alpha.,.beta.-unsaturated ketones

    Isao Shimizu;Jiro Tsuji

  • Convenient general synthetic method for 1,4- and 1,5-diketones by palladium catalyzed oxidation of α-allyl and α-3-butenyl ketones

    Jiro Tsuji;Isao Shimizu;Keiji Yamamoto

  • Palladium-Catalyzed Direct Conversion of Carboxylic Acids into Ketones with Organoboronic Acids Promoted by Anhydride Activators

    Ryuki Kakino;Hirohisa Narahashi;Isao Shimizu;Akio Yamamoto

  • Facile palladium-catalyzed decarboxylation reaction of allylic .beta.-keto esters

    Jiro Tsuji;Mohammad Nisar;Isao Shimizu

  • Allyation of carbonucleophiles with allylic carbonates under neutral conditions catalyzed by rhodium complexes

    Jiro Tsuji;Ichiro Minami;Isao Shimizu

  • Palladium-catalyzed reaction of allyl carbamates; allylation of carbonucleophiles, and protection-deprotection of amines

    Ichiro Minami;Yukihiro Ohashi;Isao Shimizu;Jiro Tsuji

  • Preparation of 1-Alkenes by the Palladium-Catalyzed Hydrogenolysis of Terminal Allylic Carbonates and Acetates with Formic Acid-Triethylamine

    Jiro Tsuji;Ichiro Minami;Isao Shimizu

  • Palladium-Catalyzed Cleavage of P-C Bonds in Quaternary Phosphonium Salts and Its Applications to Organic Synthesis

    Masato Sakamoto;Isao Shimizu;Akio Yamamoto

Frequent Co-Authors

Jiro Tsuji
Jiro Tsuji Tokyo Institute of Technology
Akio Yamamoto
Akio Yamamoto Waseda University
Toshio Kamiya
Toshio Kamiya Tokyo Institute of Technology
Fumiyuki Ozawa
Fumiyuki Ozawa Kyoto University
Takashi Takahashi
Takashi Takahashi Nagoya University

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