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Hidetoshi Tokuyama

Hidetoshi Tokuyama

D-Index & Metrics

Chemistry

D-Index
55
Citations
10379
World Ranking
12175
National Ranking
913

Overview

Hidetoshi Tokuyama is affiliated with Tohoku University in Japan. Their research primarily focuses on chemistry, with a significant number of publications concentrated in subfields such as organic chemistry, pharmacology, inorganic chemistry, molecular biology, and biochemistry.

The scientist's work encompasses several main topics including:

  • Alkaloids: synthesis and pharmacology
  • Chemical synthesis and alkaloids
  • Traditional and Medicinal Uses of Annonaceae
  • Advanced Synthetic Organic Chemistry
  • Chemical Synthesis and Analysis
  • Synthetic Organic Chemistry Methods
  • Vanadium and Halogenation Chemistry

Hidetoshi Tokuyama has contributed extensively to scholarly publications, with frequent appearances in the following venues:

  • Organic Letters
  • Organic & Biomolecular Chemistry
  • Angewandte Chemie
  • Chemical and Pharmaceutical Bulletin
  • Angewandte Chemie International Edition

Some of the recent papers by Tokuyama include:

  • A Concise Enantioselective Total Synthesis of (−)-Deoxoapodine (2020, Angewandte Chemie International Edition)
  • Total Synthesis of (−)-Lepadiformine A via Radical Translocation-Cyclization Reaction (2020, Organic Letters)
  • Divergent Total Syntheses of Isobatzellines A/B and Batzelline A (2020, Organic Letters)
  • Nitrile Synthesis by Aerobic Oxidation of Primary Amines and in situ Generated Imines from Aldehydes and Ammonium Salt with Grubbs Catalyst (2020, Advanced Synthesis & Catalysis)
  • Iron-Catalyzed Biomimetic Dimerization of Tryptophan-Containing Peptides (2023, Angewandte Chemie International Edition)

Tokuyama frequently collaborates with other researchers, notably including:

  • Hirofumi Ueda
  • Juri Sakata
  • Kei Yoshida
  • K. Okada
  • Masashi Shimomura

Overall, the research activity of Hidetoshi Tokuyama spans across chemistry and biochemistry, with a focus on synthetic organic chemistry and the study of alkaloids, among other topics related to chemical synthesis and molecular biology.

Best Publications

  • Photoinduced biochemical activity of fullerene carboxylic acid

    Hidetoshi Tokuyama;Shigeru Yamago;Eiichi Nakamura;Takashi Shiraki

  • In vivo biological behavior of a water-miscible fullerene: 14C labeling, absorption, distribution, excretion and acute toxicity

    Shigeru Yamago;Hidetoshi Tokuyama;Eiichi Nakamura;Koichi Kikuchi

  • A novel ketone synthesis by a palladium-catalyzed reaction of thiol esters and organozinc reagents

    Hidetoshi Tokuyama;Satoshi Yokoshima;Tohru Yamashita;Tohru Fukuyama

  • Fullerene–Oligonucleotide Conjugates: Photoinduced Sequence‐Specific DNA Cleavage

    Alexandre S. Boutorine;Masashi Takasugi;Claude Hélène;Hidetoshi Tokuyama

  • Stereocontrolled total synthesis of (+)-vinblastine

    Satoshi Yokoshima;Toshihiro Ueda;Satoshi Kobayashi;Ayato Sato

  • Biological Activity of Water-Soluble Fullerenes. Structural Dependence of DNA Cleavage, Cytotoxicity, and Enzyme Inhibitory Activities Including HIV-Protease Inhibition

    Eiichi Nakamura;Hidetoshi Tokuyama;Shigeru Yamago;Takashi Shiraki

  • Synthesis of secondary arylamines through copper-mediated intermolecular aryl amination.

    Kentaro Okano;Hidetoshi Tokuyama;Tohru Fukuyama

  • Radical Cyclization of 2-Alkenylthioanilides: A Novel Synthesis of 2,3-Disubstituted Indoles

    Hidetoshi Tokuyama;Tohru Yamashita;Matthew T. Reding;Yosuke Kaburagi

  • Total synthesis of (+)-yatakemycin.

    Kentaro Okano;Hidetoshi Tokuyama;Hidetoshi Tokuyama;Tohru Fukuyama

  • Total synthesis of the duocarmycins.

    Ken Yamada;Toshiki Kurokawa;Hidetoshi Tokuyama;Tohru Fukuyama

  • Synthesis of oxo- and methylene-bridged C60 dimers, the first well-characterized species containing fullerene-fullerene bonds.

    Amos B. Smith;Hidetoshi Tokuyama;Robert M. Strongin;George T. Furst

  • Acetic acid promoted metal-free aerobic carbon-carbon bond forming reactions at α-position of tertiary amines.

    Hirofumi Ueda;Kei Yoshida;Hidetoshi Tokuyama

  • Palladium-mediated synthesis of aldehydes and ketones from thiol esters

    Tohru Fukuyama;Hidetoshi Tokuyama;Hidetoshi Tokuyama;Hidetoshi Tokuyama

  • Copper-mediated aromatic amination reaction and its application to the total synthesis of natural products

    Kentaro Okano;Hidetoshi Tokuyama;Tohru Fukuyama

  • A mild copper-mediated intramolecular amination of aryl halides

    Ken Yamada;Tetsuji Kubo;Hidetoshi Tokuyama;Tohru Fukuyama

  • Auto-Tandem Catalysis in the Synthesis of Substituted Quinolines from Aldimines and Electron-Rich Olefins : Cascade Povarov-Hydrogen-Transfer Reaction

    Naoya Shindoh;Hidetoshi Tokuyama;Yoshiji Takemoto;Kiyosei Takasu

  • Total synthesis of (-)-strychnine

    Yosuke Kaburagi;Hidetoshi Tokuyama;Tohru Fukuyama

  • Synthetic Chemistry with Fullerenes. Photooxygenation of Olefins

    Hidetoshi Tokuyama;Eiichi Nakamura

  • Total synthesis of (+)-haplophytine.

    Hirofumi Ueda;Hitoshi Satoh;Koji Matsumoto;Kenji Sugimoto

  • Reduction of ethanethiol esters to aldehydes

    Hidetoshi Tokuyama;Satoshi Yokoshima;Shao Cheng Lin;Leping Li

  • A mild inter- and intramolecular amination of aryl halides with a combination of CuI and CsOAc

    Tetsuji Kubo;Chiharu Katoh;Ken Yamada;Kentaro Okano;Kentaro Okano

Frequent Co-Authors

Tohru Fukuyama
Tohru Fukuyama Nagoya University
Eiichi Nakamura
Eiichi Nakamura University of Tokyo
Hiroyuki Isobe
Hiroyuki Isobe University of Tokyo
Shigeru Yamago
Shigeru Yamago Kyoto University
Junken Aoki
Junken Aoki Tohoku University
Yoshiji Takemoto
Yoshiji Takemoto Kyoto University
Sota Sato
Sota Sato University of Tokyo
Masahiko Isaka
Masahiko Isaka National Center for Genetic Engineering and Biotechnology
Asuka Inoue
Asuka Inoue Tohoku University
Yukio Sugiura
Yukio Sugiura Kyoto University

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