World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
51
Citations
13151
World Ranking
13791
National Ranking
3579

Overview

Eric E. Simanek is affiliated with Texas Christian University in the United States and has contributed extensively to the fields of chemistry and materials science. Their research spans 26 publications in chemistry and 20 in materials science, with a focus on several interconnected subfields.

Within chemistry, Simanek's work emphasizes organic chemistry, which accounts for 23 of their publications. Materials chemistry is another major subfield, comprising 17 publications. Additional areas of study include molecular biology, polymers and plastics, and physical and theoretical chemistry.

The scientist's main research topics cover a variety of chemical and analytical processes. These include synthesis and characterization of heterocyclic compounds, X-ray diffraction applied in crystallography, and crystallization and solubility studies. Other notable topics are click chemistry and its applications, chemical synthesis and analysis, supramolecular chemistry and complexes, and aspects related to DNA and nucleic acid chemistry.

Simanek has authored or coauthored multiple papers, several of which focus on macrocycles and dendrimers. Significant recent publications include:

  • Two Decades of Triazine Dendrimers, 2021, Molecules
  • Well-Tempered Metadynamics Simulations Predict the Structural and Dynamic Properties of a Chiral 24-Atom Macrocycle in Solution, 2022, ACS Omega
  • Efficient syntheses of macrocycles ranging from 22-28 atoms through spontaneous dimerization to yield bis-hydrazones, 2020, RSC Advances
  • Computational and Experimental Evidence for Templated Macrocyclization: The Role of a Hydrogen Bond Network in the Quantitative Dimerization of 24-Atom Macrocycles, 2023, Molecules
  • A Model for the Rapid Assessment of Solution Structures for 24-Atom Macrocycles: The Impact of β-Branched Amino Acids on Conformation, 2023, The Journal of Organic Chemistry

Eric E. Simanek frequently collaborates with a set of researchers across their publications. Among these frequent coauthors are Alexander J. Menke, Benjamin G. Janesko, Hongjun Pan, Arshad Mehmood, and Joseph H. Reibenspies.

The scientist's research often appears in specific publication venues. The Cambridge Structural Database stands out as the most frequent venue, featuring seven of their publications. Other notable journals include Molecules and The Journal of Organic Chemistry, both with four publications each, ACS Medicinal Chemistry Letters with two publications, and ACS Omega with one.

Best Publications

  • Nonviral Vectors for Gene Delivery

    Meredith A. Mintzer;Eric E. Simanek

  • Noncovalent Synthesis: Using Physical-Organic Chemistry To Make Aggregates

    George M. Whitesides;Eric E. Simanek;John P. Mathias;Christopher T. Seto

  • Selectinminus signCarbohydrate Interactions: From Natural Ligands to Designed Mimics.

    Eric E. Simanek;Glenn J. McGarvey;Jill A. Jablonowski;Chi-Huey Wong

  • Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery.

    Hui Ting Chen;Michael F. Neerman;Alan R. Parrish;Eric E. Simanek

  • Cancer therapies utilizing the camptothecins: a review of the in vivo literature.

    Vincent J. Venditto;Eric E. Simanek

  • Structural Preferences of Hydrogen-Bonded Networks in Organic Solution - the Cyclic CA3.cntdot.M3 "Rosette"

    John P. Mathias;Eric E. Simanek;Jonathan A. Zerkowski;Christopher T. Seto

  • In vitro and in vivo evaluation of a melamine dendrimer as a vehicle for drug delivery.

    Michael F. Neerman;Wen Zhang;Alan R. Parrish;Eric E. Simanek

  • Self-Assembly through Hydrogen Bonding: Peripheral Crowding - A New Strategy for the Preparation of Stable Supramolecular Aggregates Based on Parallel, Connected CA3.cntdot.M3 Rosettes

    John P. Mathias;Eric E. Simanek;George M. Whitesides

  • Triazine dendrimers as drug delivery systems: From synthesis to therapy

    Jongdoo Lim;Eric E. Simanek

  • Dendrimers as drug delivery vehicles: non-covalent interactions of bioactive compounds with dendrimers

    Hannah L Crampton;Eric E Simanek

  • Engineering Nanospaces: Iterative Synthesis of Melamine‐Based Dendrimers on Amine‐Functionalized SBA‐15 Leading to Complex Hybrids with Controllable Chemistry and Porosity

    E. J. Acosta;C. S. Carr;E. E. Simanek;D. F. Shantz

  • Self-Assembly through Hydrogen Bonding: Preparation and Characterization of Three New Types of Supramolecular Aggregates Based on Parallel Cyclic CA3.cntdot.M3 "Rosettes"

    John P. Mathias;Christopher T. Seto;Eric E. Simanek;George M. Whitesides

  • Hydrogen-Bonded Tapes Based on Symmetrically Substituted Diketopiperazines: A Robust Structural Motif for the Engineering of Molecular Solids

    Serge Palacin;Donovan N. Chin;Eric E. Simanek;John C. Macdonald

  • Orthogonal, convergent syntheses of dendrimers based on melamine with one or two unique surface sites for manipulation.

    Wen Zhang;Daniel T. Nowlan;Lisa M. Thomson;and William M. Lackowski

  • Synthesis and Manipulation of Orthogonally Protected Dendrimers: Building Blocks for Library Synthesis

    Mackay B. Steffensen;Eric E. Simanek

  • Dendrimers Based on [1,3,5]-Triazines

    Mackay B. Steffensen;Emily Hollink;Frank Kuschel;Monika Bauer

  • Engineering nanospaces: ordered mesoporous silicas as model substrates for building complex hybrid materials

    David M Ford;Eric E Simanek;Daniel F Shantz

  • Dendrimers Based on Melamine. Divergent and Orthogonal, Convergent Syntheses of a G3 Dendrimer

    Wen Zhang and;Eric E. Simanek

  • Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity.

    Olivia M. Merkel;Meredith A. Mintzer;Damiano Librizzi;Olga Samsonova

  • Chemoselective building blocks for dendrimers from relative reactivity data.

    Mackay B. Steffensen;Eric E. Simanek

Frequent Co-Authors

George M. Whitesides
George M. Whitesides Harvard University
Thomas Kissel
Thomas Kissel Philipp University of Marburg
Chi-Huey Wong
Chi-Huey Wong Scripps Research Institute
David E. Bergbreiter
David E. Bergbreiter Texas A&M University
Zygmunt Gryczynski
Zygmunt Gryczynski Texas Christian University
Insung S. Choi
Insung S. Choi Korea Advanced Institute of Science and Technology
Mauri A. Kostiainen
Mauri A. Kostiainen Aalto University
Kevin J. McInnes
Kevin J. McInnes Texas A&M University
Michael V. Pishko
Michael V. Pishko Texas A&M University
Clay C. C. Wang
Clay C. C. Wang University of Southern California

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