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Christopher A. Del Negro

Christopher A. Del Negro

D-Index & Metrics

Neuroscience

D-Index
39
Citations
6945
World Ranking
8282
National Ranking
3552

Overview

Christopher A. Del Negro is affiliated with William & Mary in the United States and has a research focus primarily within the fields of neuroscience and psychology. Their work explores various aspects of neural and physiological processes related to respiratory rhythms and neuroendocrine regulation.

Their research covers several main fields of study, including:

  • Neuroscience
  • Psychology

Within these broader fields, their work delves into specific subfields such as:

  • Endocrine and Autonomic Systems
  • Cognitive Neuroscience
  • Social Psychology
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

The primary topics of Christopher A. Del Negro's research include:

  • Neuroscience of respiration and sleep
  • Neuroendocrine regulation and behavior
  • Sleep and Wakefulness Research
  • Neonatal Respiratory Health Research
  • Neural dynamics and brain function
  • Heart Rate Variability and Autonomic Control
  • Infant Health and Development

The scientist has published extensively in various academic venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annual Review of Neuroscience
  • Cell Reports
  • The Journal of Physiology
  • European Journal of Neuroscience

Recent publications reflect ongoing contributions to understanding respiratory physiology and neural control mechanisms. Selected papers include:

  • "Breathing Rhythm and Pattern and Their Influence on Emotion," 2022, Annual Review of Neuroscience
  • "Role of NaV1.6-mediated persistent sodium current and bursting-pacemaker properties in breathing rhythm generation," 2023, Cell Reports
  • "Inspiratory and sigh breathing rhythms depend on distinct cellular signalling mechanisms in the preBötzinger complex," 2024, The Journal of Physiology
  • "Transcriptomes of electrophysiologically recorded Dbx1-derived respiratory neurons of the preBötzinger complex in neonatal mice," 2022, Scientific Reports
  • "Role of Synaptic Inhibition in the Coupling of the Respiratory Rhythms that Underlie Eupnea and Sigh Behaviors," 2020, eNeuro

Collaboration is a significant aspect of this scientist's work. Frequent coauthors include:

  • Maria Cristina D. Picardo
  • Gregory D. Smith
  • Cameron J. Grover
  • Daniel S. Borrus
  • Yae K. Sugimura

Best Publications

  • Looking for inspiration: new perspectives on respiratory rhythm.

    Jack L. Feldman;Christopher A. Del Negro

  • Breathing matters

    Unknown

  • Understanding the rhythm of breathing: so near yet so far

    Jack L. Feldman;Christopher A. Del Negro;Paul A. Gray

  • Sodium and Calcium Current-Mediated Pacemaker Neurons and Respiratory Rhythm Generation

    Christopher A. Del Negro;Consuelo Morgado-Valle;John A. Hayes;Devin D. Mackay

  • Respiratory rhythm generation in neonatal and adult mammals: the hybrid pacemaker-network model.

    Jeffrey C Smith;Robert J Butera;Naohiro Koshiya;Christopher Del Negro

  • Persistent sodium current, membrane properties and bursting behavior of pre-bötzinger complex inspiratory neurons in vitro.

    Christopher A. Del Negro;Naohiro Koshiya;Robert J. Butera;Jeffrey C. Smith

  • Respiratory rhythm: an emergent network property?

    Christopher A Del Negro;Consuelo Morgado-Valle;Jack L Feldman

  • Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice.

    Ryland W. Pace;Devin D. Mackay;Jack L. Feldman;Christopher A. Del Negro;Christopher A. Del Negro

  • Developmental Origin of preBötzinger Complex Respiratory Neurons

    Paul A Gray;John A Hayes;Guang Y Ling;Isabel Llona

  • Calcium-activated nonspecific cation current and synaptic depression promote network-dependent burst oscillations

    Jonathan E. Rubin;John A. Hayes;Jeffrey L. Mendenhall;Christopher A. Del Negro

  • Models of respiratory rhythm generation in the pre-Bötzinger complex. III. Experimental tests of model predictions

    Christopher A. Del Negro;Sheree M. Johnson;Robert J. Butera;Jeffrey C. Smith

  • Flufenamic acid as an ion channel modulator

    Romain Guinamard;Christophe Simard;Christopher Del Negro

  • Role of persistent sodium current in mouse preBötzinger Complex neurons and respiratory rhythm generation

    Ryland W. Pace;Devin D. Mackay;Jack L. Feldman;Christopher A. Del Negro;Christopher A. Del Negro

  • Ionic Basis for Serotonin-Induced Bistable Membrane Properties in Guinea Pig Trigeminal Motoneurons

    Chie-Fang Hsiao;Christopher A. Del Negro;Peggy R. Trueblood;Scott H. Chandler

  • Periodicity, Mixed-Mode Oscillations, and Quasiperiodicityin a Rhythm-Generating Neural Network

    Christopher A. Del Negro;Christopher G. Wilson;Robert J. Butera;T. Henrique Rigatto

  • Phosphatidylinositol 4,5‐bisphosphate regulates inspiratory burst activity in the neonatal mouse preBötzinger complex

    Erin A. Crowder;Margaret S. Saha;Ryland W. Pace;Honglu Zhang

  • Laser ablation of Dbx1 neurons in the pre-Bötzinger Complex stops inspiratory rhythm and impairs output in neonatal mice

    Xueying Wang;John A Hayes;Ann L Revill;Hanbing Song

  • Evidence for a novel bursting mechanism in rodent trigeminal neurons.

    Christopher A. Del Negro;Chie-Fang Hsiao;Scott H. Chandler;Alan Garfinkel

  • Neurokinin Receptor-Expressing Pre-Botzinger Complex Neurons in Neonatal Mice Studied In Vitro

    John A. Hayes;Christopher A. Del Negro

  • Interactions of persistent sodium and calcium-activated nonspecific cationic currents yield dynamically distinct bursting regimes in a model of respiratory neurons

    Justin R. Dunmyre;Christopher A. Del Negro;Jonathan E. Rubin

  • Author response: Laser ablation of Dbx1 neurons in the pre-Bötzinger complex stops inspiratory rhythm and impairs output in neonatal mice

    Xueying Wang;John A Hayes;Ann L Revill;Hanbing Song

Frequent Co-Authors

Jack L. Feldman
Jack L. Feldman University of California, Los Angeles
Jeffrey C. Smith
Jeffrey C. Smith National Institutes of Health
Gregory D. Funk
Gregory D. Funk University of Alberta
Scott H. Chandler
Scott H. Chandler University of California, Los Angeles
Huda Y. Zoghbi
Huda Y. Zoghbi Baylor College of Medicine
Jonathan E. Rubin
Jonathan E. Rubin University of Pittsburgh
Joshua G. Corbin
Joshua G. Corbin Children’s National Health System
Klaus Ballanyi
Klaus Ballanyi University of Alberta
John Rinzel
John Rinzel New York University

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