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Biology and Biochemistry

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61
Citations
16243
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11213
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44

Overview

Ariff Bongso is a researcher affiliated with the National University of Singapore in Singapore. Their work primarily spans the field of Medicine, with a focus on Genetics, Rehabilitation, Molecular Biology, Reproductive Medicine, and Dermatology. The research topics associated with their publications include mesenchymal stem cell research, wound healing and treatments, pluripotent stem cells research, dermatologic treatments and research, neurogenesis and neuroplasticity mechanisms, sperm and testicular function, and reproductive biology and fertility.

Bongso's recent papers illustrate a strong focus on stem cell research and its applications. The prominent publications include:

  • Inhibition of growth of Asian keloid cells with human umbilical cord Wharton's jelly stem cell-conditioned medium (2020), published in Stem Cell Research & Therapy
  • Allogeneic human umbilical cord Wharton's jelly stem cells increase several-fold the expansion of human cord blood CD34+ cells both in vitro and in vivo (2020), published in Stem Cell Research & Therapy
  • Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men (2021), published in Endocrine
  • Hypoxic Wharton's Jelly Stem Cell Conditioned Medium Induces Immunogenic Cell Death in Lymphoma Cells (2020), published in Stem Cells International
  • Tissues derived from reprogrammed Wharton's jelly stem cells of the umbilical cord as a platform to study gestational diabetes mellitus (2020), published in Stem Cell Research

Their work has been disseminated through several recognized scientific venues, including Stem Cell Research & Therapy, Endocrine, Stem Cells International, Stem Cell Research, and Research Square.

Collaboration has been a part of Bongso's research approach, with frequent coauthors being:

  • Arijit Biswas
  • Chui-Yee Fong
  • Arjunan Subramanian
  • Shu Uin Gan
  • Mahesh Choolani

The areas of study they contribute to indicate a cross-disciplinary approach integrating molecular biology and genetics with clinical research in dermatology and reproductive health. Their research includes the exploration of stem cells derived from Wharton's jelly, emphasizing potential therapeutic applications in wound healing, immunogenic responses in cancer cells, and fertility parameters.

Best Publications

  • Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.

    Benjamin E. Reubinoff;Martin F. Pera;Chui-Yee Fong;Alan Trounson

  • Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells.

    Mark Richards;Chui-Yee Fong;Woon-Khiong Chan;Peng-Cheang Wong

  • Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes.

    Sunil Rangappa;Chen Fen;Eng Hin Lee;Ariff Bongso

  • The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE

    Mark Richards;Siew‐Peng Tan;Jee‐Hian Tan;Woon‐Khiong Chan

  • Isolation and culture of inner cell mass cells from human blastocysts.

    Ariff Bongso;Chui-Yee Fong;Soon-Chye Ng;Shan Ratnam

  • Comparative Evaluation of Various Human Feeders for Prolonged Undifferentiated Growth of Human Embryonic Stem Cells

    Mark Richards;Shawna Tan;Chui-Yee Fong;Arjit Biswas

  • Human Wharton’s Jelly Stem Cells Have Unique Transcriptome Profiles Compared to Human Embryonic Stem Cells and Other Mesenchymal Stem Cells

    Chui-Yee Fong;Li-Ling Chak;Arijit Biswas;Jee-Hian Tan

  • Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

    Hwee Ying Lim;Sheau Yng Lim;Chek Kun Tan;Chung Hwee Thiam

  • Centrioles in the beginning of human development.

    A H Sathananthan;I Kola;J Osborne;A Trounson

  • The therapeutic potential, challenges and future clinical directions of stem cells from the Wharton's jelly of the human umbilical cord.

    Ariff Bongso;Ariff Bongso;Chui-Yee Fong;Chui-Yee Fong

  • Improved quality of human embryos when co-cultured with human ampullary cells

    Ariff Bongso;Ng Soon-Chye;Henry Sathananthan;Ng Poh Lian

  • Teratomas from pluripotent stem cells: A clinical hurdle

    Chui-Yee Fong;Kalamegam Gauthaman;Ariff Bongso

  • Comparative growth behaviour and characterization of stem cells from human Wharton's jelly.

    CY Fong;M Richards;N Manasi;A Biswas

  • Pregnancy after transfer of sperm under zona.

    Soon-Chye Ng;Ariff Bongso;ShanS. Ratnam;Henry Sathananthan

  • Taking stem cells to the clinic: Major challenges

    Ariff Bongso;Chui-Yee Fong;Kalamegam Gauthaman

  • Separation of SSEA-4 and TRA-1–60 Labelled Undifferentiated Human Embryonic Stem Cells from A Heterogeneous Cell Population Using Magnetic-Activated Cell Sorting (MACS) and Fluorescence-Activated Cell Sorting (FACS)

    Chui Yee Fong;Gary S. L. Peh;Kalamegam Gauthaman;Ariff Bongso

  • Embryonic stem cells

    Benjamin Eithan Reubinoff;Martin Frederick Pera;Chui-Yee Fong;Alan Osborne Trounson

  • An efficient and safe xeno-free cryopreservation method for the storage of human embryonic stem cells.

    Mark Richards;Chui‐Yee Fong;Shawna Tan;Woon‐Khiong Chan

  • Derivation efficiency, cell proliferation, freeze-thaw survival, stem-cell properties and differentiation of human Wharton's jelly stem cells.

    Chui-Yee Fong;Arjunan Subramanian;Arijit Biswas;Kalamegam Gauthaman

  • Human umbilical cord Wharton's jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitro.

    Kalamegam Gauthaman;Fong Chui Yee;Suganya Cheyyatraivendran;Arijit Biswas

Frequent Co-Authors

Alan O Trounson
Alan O Trounson Monash University
Jayarama Reddy Venugopal
Jayarama Reddy Venugopal Universiti Malaysia Pahang
Seeram Ramakrishna
Seeram Ramakrishna Tsinghua University
Martin F. Pera
Martin F. Pera Walter and Eliza Hall Institute of Medical Research
Nguan Soon Tan
Nguan Soon Tan Nanyang Technological University
Matthew Collin
Matthew Collin Newcastle University
Kandiah Jeyaseelan
Kandiah Jeyaseelan National University of Singapore
Wolfgang Weninger
Wolfgang Weninger Medical University of Vienna
Florent Ginhoux
Florent Ginhoux Agency for Science, Technology and Research
Michael Poidinger
Michael Poidinger Murdoch Children's Research Institute

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