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Medicinal Chemistry
H-index 14

Medicinal Chemistry

1573-4064

Published by: Bentham Science

https://benthamscience.com/journals/medicinal-chemistry/

Ranking & Metrics

Discipline name Position Best Scientists Publications D-Index
Chemistry 590 39 54 13

Additional Metrics

Number of Best Scientists*: 71
Documents by Best Scientists*: 89
Top 100 Ranked Scientists*: 0
SCIMAGO H-index: 51
SCIMAGO SJR: 0.38
Impact Factor: 2.6

Overview

Top Research Topics at Medicinal Chemistry?

The journal mainly tackles studies in Stereochemistry, Pharmacology, Biochemistry, Combinatorial chemistry and In vitro. Medicinal Chemistry holds forums on Stereochemistry that merges themes from other disciplines such as Structure–activity relationship and Cytotoxicity. Discussions in the journal are anchored in the subject of Pharmacology and the similar topic of In vivo.

Biochemistry studies presented include Enzyme and Antioxidant. It focuses on Combinatorial chemistry as well as the interrelated topic of Antimicrobial. The work tackled in the journal goes beyond the discipline of Antimicrobial as it also encompasses Antibacterial activity.

The study on In vitro presented in it intersects with subjects under the field of Cell culture.

  • Stereochemistry (23.72%)
  • Pharmacology (16.65%)
  • Biochemistry (14.84%)

What are the most cited papers published in the journal?

  • Impacts of bioinformatics to medicinal chemistry. (426 citations)
  • Curcumin is an Inhibitor of p300 Histone Acetylatransferase (236 citations)
  • Protease inhibitors in the clinic. (234 citations)

Research areas of the most cited articles at Medicinal Chemistry:

The most cited publications mostly deal with topics like Biochemistry, Pharmacology, Stereochemistry, Computational biology and Structure–activity relationship. In addition to Pharmacology research, the most cited articles aim to explore topics under Cell culture, Cancer and Chemotherapy. While the primary focus in the most cited articles is Stereochemistry, they also dissect topics surrounding Cytotoxicity and Cytotoxic T cell as a whole.

What topics the last edition of the journal is best known for?

  • Enzyme
  • Gene
  • Internal medicine

The previous edition focused in particular on these issues:

The journal generally zeroes in on subjects such as Docking (molecular), Combinatorial chemistry, Cytotoxicity, Biochemistry and In vitro. Research in Docking (molecular) discussed is concerned with the study of Stereochemistry as a whole. The studies on Stereochemistry discussed can also contribute to research in the domains of Acarbose and Active site.

It goes beyond the discussion of Combinatorial chemistry as it connects it with closely related disciplines like

  • Biological activity, which have a strong connection to Quantitative structure–activity relationship,
  • Antimicrobial which intersects with area such as Antibacterial activity.. Biochemistry research discussed connects with the study of Cell culture. Medicinal Chemistry addresses concerns in the field of In vitro by exploring it in line with topics in Pharmacology which intersect with Antioxidant subjects.

The most cited articles from the last journal are:

  • Anti-Cholinesterase Activity of Chalcone Derivatives: Synthesis, In Vitro Assay and Molecular Docking Study (5 citations)
  • Synthesis and Antimicrobial Activity of Novel 1, 2, 4-Triazolopyrimidofuroquinazolinones from Natural Furochromones (Visnagenone and Khellinone). (4 citations)
  • Synthesis, Antitrypanosomal and Antimycobacterial Activities of Coumarin N-acylhydrazonic Derivatives. (4 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

The top authors publishing in Medicinal Chemistry (based on the number of publications) are:

  • Khalid Mohammed Khan (39 papers) published 2 papers at the last edition, 2 less than at the previous edition,
  • Shahnaz Perveen (25 papers) published 1 paper at the last edition, 1 less than at the previous edition,
  • Muhammad Iqbal Choudhary (21 papers) absent at the last edition,
  • Kuo-Chen Chou (18 papers) absent at the last edition,
  • Mohammad Amjad Kamal (17 papers) published 1 paper at the last edition, 4 less than at the previous edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Only papers with recognized affiliations are considered

The top affiliations publishing in Medicinal Chemistry (based on the number of publications) are:

  • University of Karachi (59 papers) published 6 papers at the last edition, 4 less than at the previous edition,
  • King Abdulaziz University (21 papers) published 2 papers at the last edition, 3 less than at the previous edition,
  • COMSATS Institute of Information Technology (21 papers) published 5 papers at the last edition, 4 more than at the previous edition,
  • Oswaldo Cruz Foundation (17 papers) published 1 paper at the last edition, 2 less than at the previous edition,
  • Shandong University (17 papers) absent at the last edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 24.81% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 19.59% were posted by at least one author from the top 10 institutions publishing in the journal. Another 10.31% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 12.37% of all publications and 57.73% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

  • Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
  • Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
  • Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
  • Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
  • Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Top Publications

  • Synthesis, In vitro α-Glucosidase Inhibitory Potential and Molecular Docking Studies of 2-Amino-1,3,4-Oxadiazole Derivatives

    Hayat Ullah;Fazal Rahim;Muhammad Taha;Raffaqat Hussain

    (2020)
    37 Citations
  • Quinone-Based Drugs: An Important Class of Molecules in Medicinal Chemistry.

    Vitor F Ferreira;Alcione S de Carvalho;Patricia G Ferreira;Carolina G S Lima

    (2021)
    28 Citations
  • Hybrids of Coumarin Derivatives as Potent and Multifunctional Bioactive Agents: A Review

    Ioannis Fotopoulos;Dimitra Hadjipavlou-Litina

    (2020)
    26 Citations
  • Chalcones: As potent α-amylase enzyme inhibitors; synthesis, in vitro, and in silico studies.

    (2020)
    25 Citations
  • 2-Mercapto Benzothiazole Derivatives: As Potential Leads for the Diabetic Management.

    Saeed Ullah;Salma Mirza;Uzma Salar;Shafqat Hussain

    (2020)
    24 Citations
  • Bis-1,3,4-Oxadiazole Derivatives as Novel and Potential Urease Inhibitors; Synthesis, In Vitro, and In Silico Studies.

    (2022)
    20 Citations
  • 1,2,3-Triazole- and Quinoline-Based Hybrids with Potent Antiplasmodial Activity.

    Isabela A Graciano;Alcione S de Carvalho;Fernando de Carvalho da Silva;Vitor F Ferreira

    (2021)
    18 Citations
  • Antidiabetic Activity of Dihydropyrimidine Scaffolds and Structural Insight by Single Crystal X-ray Studies.

    Keshab M. Bairagi;Nancy Safwat Younis;Promise Madu Emeka;Ekta Sangtani

    (2020)
    16 Citations
  • Design and Synthesis of Novel Sulfonamide-Derived Triazoles and Bioactivity Exploration.

    Shi-Chao He;Hui-Zhen Zhang;Hai-Juan Zhang;Qing Sun

    (2020)
    14 Citations
  • Novel Coumarin Containing Dithiocarbamate Derivatives as Potent α-Glucosidase Inhibitors for Management of Type 2 Diabetes.

    Marjan Mollazadeh;Maryam Mohammadi-Khanaposhtani;Yousef Valizadeh;Afsaneh Zonouzi

    (2021)
    14 Citations

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