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Human Molecular Genetics
H-index 43

Human Molecular Genetics

0964-6906

Published by: Oxford University Press

https://academic.oup.com/hmg

Ranking & Metrics

Discipline name Position Best Scientists Publications D-Index
Genetics 21 563 496 36
Molecular Biology 45 96 124 24

Additional Metrics

Number of Best Scientists*: 1808
Documents by Best Scientists*: 988
Top 100 Ranked Scientists*: 84
SCIMAGO H-index: 307
SCIMAGO SJR: 1.56
Impact Factor: 3.2

Overview

Top Research Topics at Human Molecular Genetics?

The discussions in Human Molecular Genetics mainly cover the fields of Genetics, Gene, Molecular biology, Cell biology and Mutation. It encompasses presentations on Genetics, specifically Gene mapping, Locus (genetics), Allele, Single-nucleotide polymorphism and Exon. While work presented in Human Molecular Genetics provided substantial information on Gene mapping, it also covered topics in Genetic marker, Microsatellite and Genetic linkage.

In addition to Genetic marker research, it aims to explore topics under Allele frequency and Dinucleotide Repeat. The Allele study tackling the subject of Haplotype is the focus of Human Molecular Genetics. The journal focuses on Exon research which is adjacent to topics in RNA splicing.

Gene expression, Regulation of gene expression and Genome are all topics related to Gene research discussed. Endocrinology, Biochemistry and Neurodegeneration are some topics wherein Cell biology research discussed in the journal have an impact. Human Molecular Genetics explores issues in Mutation which can be linked to other research areas like Phenotype and Mutant.

  • Genetics (52.99%)
  • Gene (21.85%)
  • Molecular biology (20.66%)

What are the most cited papers published in the journal?

  • Non-coding RNA (1690 citations)
  • The DNA methyltransferases of mammals (1689 citations)
  • Mutation of human short tandem repeats (1402 citations)

Research areas of the most cited articles at Human Molecular Genetics:

The most cited papers are organized to reinforce research efforts on Genetics, Gene, Molecular biology, Mutation and Cell biology. The journal papers explore issues in Mutation which can be linked to other research areas like Endocrinology and Mutant. The studies on Cell biology discussed at the journal papers can also contribute to research in the domains of Huntingtin and Biochemistry.

What topics the last edition of the journal is best known for?

  • Gene
  • Mutation
  • Enzyme

The previous edition focused in particular on these issues:

The foci of the journal are Cell biology, Genetics, Gene, Phenotype and Genome-wide association study. The research on Cell biology featured in it combines topics in other fields like RNA, Mutant, Gene knockdown and Neurodegeneration. Topics like Missense mutation, Allele, Locus (genetics), Mutation and Exome sequencing are tackled as part of the discussions on Genetics.

In the Gene research discussed, Gene expression, Transcriptome and Epigenetics are all tackled. The Genome-wide association study research presented in Human Molecular Genetics explores the relationship between Genetic association and the closely related topic of Disease. Human Molecular Genetics centers on topics in Single-nucleotide polymorphism, with a focus on SNP.

The most cited articles from the last journal are:

  • Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses. (10 citations)
  • Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence. (9 citations)
  • Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles. (8 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

The top authors publishing in Human Molecular Genetics (based on the number of publications) are:

  • Michael R. Hayden (59 papers) absent at the last edition,
  • Yusuke Nakamura (58 papers) absent at the last edition,
  • Charis Eng (56 papers) published 4 papers at the last edition, 1 less than at the previous edition,
  • Kay E. Davies (54 papers) published 2 papers at the last edition,
  • James F. Gusella (51 papers) published 2 papers at the last edition the same number as at the previous edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Only papers with recognized affiliations are considered

The top affiliations publishing in Human Molecular Genetics (based on the number of publications) are:

  • National Institutes of Health (663 papers) published 15 papers at the last edition the same number as at the previous edition,
  • French Institute of Health and Medical Research (547 papers) published 9 papers at the last edition, 5 more than at the previous edition,
  • Harvard University (537 papers) published 12 papers at the last edition, 3 less than at the previous edition,
  • Boston Children's Hospital (391 papers) published 25 papers at the last edition, 7 more than at the previous edition,
  • University of Cambridge (387 papers) published 9 papers at the last edition, 2 more than at the previous edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 2.25% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 27.38% were posted by at least one author from the top 10 institutions publishing in the journal. Another 9.22% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 14.70% of all publications and 48.70% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

  • Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
  • Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
  • Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
  • Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
  • Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Top Publications

  • Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1

    Ricardo Mouro Pinto;Larissa Arning;James V. Giordano;Pedram Razghandi

    (2020)
    113 Citations
  • Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

    (2022)
    109 Citations
  • Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.

    Wenfei Liu;Orjona Taso;Rui Wang;Sevinc Bayram

    (2020)
    100 Citations
  • Single cell transcriptome profiling of the human alcohol-dependent brain.

    Eric Brenner;Gayatri R Tiwari;Manav Kapoor;Yunlong Liu

    (2020)
    87 Citations
  • Novel genes and sex differences in COVID-19 severity

    (2022)
    85 Citations
  • Gene therapy for Alzheimer's disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation.

    Ana Griciuc;Anthony N Federico;Jeyashree Natasan;Angela M Forte

    (2020)
    85 Citations
  • Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity.

    Lingyan Chen;Lingyan Chen;Yong-Fei Wang;Lu Liu;Lu Liu;Adrianna Bielowka

    (2020)
    79 Citations
  • Detailed stratified GWAS analysis for severe COVID-19 in four European populations

    (2022)
    72 Citations

Best Scientists Contributing to This Journal

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